Multiple antenna ablation apparatus and method

• US 5,728,143 A
• Filed: 02/14/1996
• Issued: 03/17/1998
• Est. Priority Date: 08/15/1995
• Status: Expired due to Term

• Current Assignee: AngioDynamics, Inc.
• Original Assignee: Rita Medical Systems Incorporated (AngioDynamics, Inc.)
• Inventors: Gough, Edward J., Stein, Alan A.
• Primary Examiner(s): Cohen, Lee S.
• Assistant Examiner(s): Peffley, Michael
• Application Number:
  US08/605,323
• Time in Patent Office: 762 Days
• Field of Search: 606/41, 606/42, 606/45-50, 607/115, 607/116, 607/100-102, 607/154, 607/156, 128/642, 604/22
• US Class Current: 607/101
• CPC Class Codes: A61B 18/1206 Generators therefor
• CPC Class Codes: A61B 18/14 Probes or electrodes therefor
• CPC Class Codes: A61B 18/1402 Probes for open surgery
• CPC Class Codes: A61B 18/1477 Needle-like probes
• CPC Class Codes: A61B 18/1482 having a long rigid shaft for accessing the inner body transcutaneously in minimal invasive surgery, e.g. laparoscopy
• CPC Class Codes: A61B 18/1485 having a short rigid shaft for accessing the inner body through natural openings
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 2017/00022 Sensing or detecting at the treatment site
• CPC Class Codes: A61B 2017/00101 using an array of thermosensors
• CPC Class Codes: A61B 2018/00011 with fluids
• CPC Class Codes: A61B 2018/00023 closed, i.e. without wound contact by the fluid
• CPC Class Codes: A61B 2018/00196 reciprocating lengthwise
• CPC Class Codes: A61B 2018/00273 Anchoring means for temporary attachment of a device to tissue
• CPC Class Codes: A61B 2018/00452 Skin
• CPC Class Codes: A61B 2018/00476 Hair follicles
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00666 using a threshold value
• CPC Class Codes: A61B 2018/00678 upper
• CPC Class Codes: A61B 2018/00702 : Power or energy
• CPC Class Codes: A61B 2018/00708 : switching the power on or off
• CPC Class Codes: A61B 2018/00726 : Duty cycle
• CPC Class Codes: A61B 2018/00744 : Fluid flow
• CPC Class Codes: A61B 2018/00761 : Duration
• CPC Class Codes: A61B 2018/00779 : Power or energy
• CPC Class Codes: A61B 2018/00791 : Temperature
• CPC Class Codes: A61B 2018/00797 : measured by multiple temperature sensors
• CPC Class Codes: A61B 2018/00827 : Current
• CPC Class Codes: A61B 2018/00875 : Resistance or impedance
• CPC Class Codes: A61B 2018/00892 : Voltage
• CPC Class Codes: A61B 2018/124 : switching the output to different electrodes, e.g. sequentially
• CPC Class Codes: A61B 2018/1253 : monopolar
• CPC Class Codes: A61B 2018/126 : bipolar
• CPC Class Codes: A61B 2018/1425 : Needle
• CPC Class Codes: A61B 2018/143 : multiple needles
• CPC Class Codes: A61B 2018/1432 : curved
• CPC Class Codes: A61B 2018/1435 : Spiral
• CPC Class Codes: A61B 2018/1472 : for use with liquid electrolyte, e.g. virtual electrodes
• CPC Class Codes: A61B 2018/162 : located on the probe body
• CPC Class Codes: A61B 2218/002 : Irrigation
• CPC Class Codes: A61M 25/007 : Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
• CPC Class Codes: A61M 3/0279 : Cannula; Nozzles; Tips; their connection means
• CPC Class Codes: A61N 1/06 : for high-frequency therapy
• CPC Class Codes: A61N 1/403 : for thermotherapy, e.g. hyperthermia
• CPC Class Codes: A61N 5/04 : Radiators for near-field treatment
• CPC Class Codes: A61N 5/045 : specially adapted for treatment inside the body

Abstract

A multiple antenna ablation apparatus includes an electromagnetic energy source, a trocar including a distal end, and a hollow lumen extending along a longitudinal axis of the trocar, and a multiple antenna ablation device with three or more antennas. The antennas are initially positioned in the trocar lumen as the trocar is introduced through tissue. At a selected tissue site the antennas are deployable from the trocar lumen in a lateral direction relative to the longitudinal axis. Each of the deployed antennas has an electromagnetic energy delivery surface of sufficient size to, (i) create a volumetric ablation between the deployed antennas, and (ii) the volumetric ablation is achieved without impeding out any of the deployed antennas when 10 to 50 watts of electromagnetic energy is delivered from the electromagnetic energy source to the multiple antenna ablation device. At least one cable couples the multiple antenna ablation device to the electromagnetic energy source.

Claims

1. An ablation treatment apparatus, comprising:

a trocar including a distal end sharp enough to pierce tissue, and a hollow lumen extending along a longitudinal axis of the trocar;

a multiple antenna ablation device including three or more antennas, each antenna including a distal portion and each antenna being at least partially positioned in the trocar lumen as the trocar is introduced through tissue, at least a part of each distal portion of a deployed antenna being configured to be deployable from the trocar lumen at a selected tissue site with at least one radius of curvature and having a deployed antenna electromagnetic energy delivery surface, wherein a collective size of the deployed antennas'"'"' electromagnetic energy delivery surfaces is sufficient to create a volumetric ablation between the deployed antennas without impeding out a deployed antenna when 10 to 50 watts of electromagnetic energy is delivered from an electromagnetic energy source to the multiple antenna ablation device; and

at least one cable coupling the multiple antenna ablation device to the electromagnetic energy source.

2. The apparatus of claim 1, wherein the collective size of the deployed antennas'"'"' electromagnetic energy delivery surfaces is sufficient to create a volumetric ablation between the deployed antennas without impeding out a deployed antenna when 10 to 30 watts of electromagnetic energy is delivered from the electromagnetic energy source to the multiple antenna ablation device.

3. The apparatus of claim 1, wherein the collective size of the deployed antennas'"'"' electromagnetic energy delivery surfaces is sufficient to create a volumetric ablation between the deployed antennas without impeding out a deployed antenna when 15 to 20 watts of electromagnetic energy is delivered from the electromagnetic energy source to the multiple antenna ablation device.

4. The apparatus of claim 1, wherein each of the antennas is coupled to the electromagnetic energy source.

5. The apparatus of claim 1, wherein the trocar has an outer diameter no greater than 13 gauge.

6. The apparatus of claim 1, wherein the trocar has an outer diameter no greater than 14 gauge.

7. The apparatus of claim 1, wherein the trocar has an outer diameter no greater than 15 gauge.

8. The apparatus of claim 1, wherein four deployed antennas are deployed from the trocar at the selected tissue mass.

9. The apparatus of claim 8, wherein at least one deployed antenna is deployed into the selected tissue mass from the trocar distal end and at least one deployed antenna is deployed into the selected tissue mass from a side port.

10. The apparatus of claim 1, wherein five deployed antennas are deployed from the trocar at the selected tissue mass.

11. The apparatus of claim 1, wherein six deployed antennas are deployed from the trocar at the selected tissue mass.

12. The apparatus of claim 1, wherein at least two of the deployed antennas are deployed out of the trocar distal end.

13. The apparatus of claim 1, wherein the trocar includes one or more side ports formed in a body of the trocar.

14. The apparatus of claim 1, wherein the antennas are RF electrodes and the electromagnetic energy source is an RF energy source.

15. The apparatus of claim 1, wherein the multiple antenna ablation device operates in a monopolar mode.

16. The apparatus of claim 1, wherein the multiple antenna ablation device operates in a bipolar mode.

17. The apparatus of claim 1, wherein the apparatus is switchable between bipolar and monopolar operation.

18. The apparatus of claim 1 wherein at least a part of a distal portion of each deployed antenna is constructed to be structurally less rigid than the trocar.

19. The apparatus of claim 1, further comprising:

a sensor at least partially positioned on an exterior surface of a deployed antenna.

20. The apparatus of claim 1, further comprising:

an insulation layer positioned in a surrounding relationship around at least a portion of an exterior of the trocar.

21. The apparatus of claim 20, wherein a distal end of the insulation layer is removed from the distal end of the trocar and create an electromagnetic energy delivery surface at the distal end of the trocar.

22. The apparatus of claim 1, wherein the trocar lumen is coupled to an infusion medium source to receive an infusion medium.

23. The apparatus of claim 1, further comprising:

a cooling element coupled to at least a portion of the trocar.

24. The apparatus of claim 23, wherein the cooling element comprises:

a structure at least partially positioned in the trocar including at least one channel configured to receive a cooling medium.

25. The apparatus of claim 24, wherein the cooling medium is recirculated through the channel.

26. An ablation treatment apparatus, comprising:

a trocar including a distal end sharp enough to pierce tissue, and a hollow lumen extending along a longitudinal axis of the trocar;

a multiple antenna ablation device including a plurality of antennas, each antenna including a distal portion and each antenna being at least partially positioned in the trocar lumen as the trocar is introduced through tissue, at least a part of each distal portion of a deployed antenna being configured to be deployable from the trocar lumen at a selected tissue site with at least one radius of curvature, wherein the plurality of antennas includes a sufficient number of antennas to create an ablation volume between the antennas in the selected tissue site without impeding out the plurality of antennas when 10 to 50 watts of electromagnetic energy is delivered from the electromagnetic energy source to the plurality of antennas; and

at least one cable coupling the multiple antenna ablation device to the electromagnetic energy source.

27. The apparatus of claim 26, wherein the trocar has an outer diameter no greater than 15 gauge.

28. The apparatus of claim 26, wherein the multiple antenna ablation device is an RF device.

29. The apparatus of claim 28, wherein the multiple antenna ablation device operates in a monopolar mode.

30. The apparatus of claim 28, wherein the multiple antenna ablation device operates in a bipolar mode.

31. The apparatus of claim 28, wherein the multiple antenna ablation device is switchable between bipolar and monopolar operation.

32. A method for creating a volumetric ablation in a selected tissue mass, comprising:

providing a multiple antenna ablation apparatus including a trocar with a trocar lumen, a plurality of antennas deployable from the lumen, and an electromagnetic energy source coupled to the plurality of antennas;

inserting the trocar into the selected tissue mass with the plurality of antennas positioned in the trocar lumen;

advancing the plurality of antennas from the trocar lumen in a lateral direction relative to a longitudinal axis of the trocar into the selected tissue mass;

delivering 10 to 50 watts of electromagnetic energy from the electromagnetic energy source to the plurality of antennas without impeding out an antenna of the plurality of antennas; and

creating the volumetric ablation in the selected tissue mass.

33. The method of claim 32, wherein the ablation volume is a spheroid geometry.

34. The method of claim 32, wherein the ablation volume is a spherical geometry.

35. The method of claim 32, wherein the ablation volume is a partial spherical geometry.

36. The method of claim 32, wherein the ablation volume is formed continuously between adjacently deployed antennas of the plurality.

37. The method of claim 32, wherein the trocar has an outer diameter no greater than 15 gauge.

38. The method of claim 32, wherein each antenna of the plurality has an electromagnetic energy delivery surface size sufficient to receive 10 to 50 watts of electromagnetic energy from the electromagnetic energy source.