Perfusion hyperthermia treatment system and method
First Claim
1. A perfusion hyper/hypothermia treatment system comprising:
- a computer system;
a source of physiological fluid having a temperature;
an interface coupled to receive a plurality of temperature signals from temperature sensors, the interface coupled to the computer system, the temperature signals representative of temperatures at each of a plurality of patient locations on or within a patient;
a converter coupled to the interface, and that generates at least one temperature value representative of at least one of the temperatures;
a comparator coupled to receive the temperature value and to receive a set of stored parameters in the computer system, and to generate a comparison value;
a heat exchanger the source of physiological fluid;
a signal generator coupled to the computer system which generates a control signal that is coupled to the heat exchanger to control a change in the temperature of the physiological fluid based on the comparison value; and
a perfusion mechanism, in fluid communication with the heat exchanger, that receives the physiological fluid after a temperature change has been affected and perfuses the physiological fluid into the patient.
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Accused Products
Abstract
Method and apparatus to automatically monitor and control a perfusion hyperthermia treatment using a system including one or more programmed computers, and mechanical and sensor subsystems. The system includes a fluid path between a patient and an external fluid-treatment subsystem, wherein control of the external fluid-treatment subsystem includes feedback from sensors coupled to the patient. The resulting integrated system provides automated monitoring and control of the patient, the external fluid-treatment subsystem, and the treatment. In one embodiment, the fluid passing between the patient and the external fluid-treatment subsystem is blood. In one embodiment, an apparatus and method are provided for using a computerized system for a perfusion hyper/hypothermia treatment of a patient which obtains a body fluid having a temperature. A plurality of temperature signals representative of temperatures at each of a plurality of patient locations on or within the patient are coupled to the computer system. Measured temperatures are compared to a set of stored parameters in the computer system to generate a comparison value which controls a change in the temperature of the body fluid. The body fluid is then perfused into the patient to either warm, cool, or maintain the current temperature of the patient. In one such embodiment, the body fluid is blood withdrawn from the patient. In another such embodiment, the body fluid is saline.
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Citations
20 Claims
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1. A perfusion hyper/hypothermia treatment system comprising:
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a computer system; a source of physiological fluid having a temperature; an interface coupled to receive a plurality of temperature signals from temperature sensors, the interface coupled to the computer system, the temperature signals representative of temperatures at each of a plurality of patient locations on or within a patient; a converter coupled to the interface, and that generates at least one temperature value representative of at least one of the temperatures; a comparator coupled to receive the temperature value and to receive a set of stored parameters in the computer system, and to generate a comparison value; a heat exchanger the source of physiological fluid; a signal generator coupled to the computer system which generates a control signal that is coupled to the heat exchanger to control a change in the temperature of the physiological fluid based on the comparison value; and a perfusion mechanism, in fluid communication with the heat exchanger, that receives the physiological fluid after a temperature change has been affected and perfuses the physiological fluid into the patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A perfusion hyper/hypothermia treatment system comprising:
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a computer system, the computer system holding a set of stored parameters, the set of stored parameters including a minimum and a maximum temperature parameter, and a minimum and a maximum temperature-rate-of-change parameter; a source of physiological fluid having a temperature, wherein the physiological fluid is blood withdrawn from the patient; an interface, coupled to receive a plurality of temperature signals from temperature sensors, the interface coupled to the computer system, the temperature signals representative of temperatures at each of a plurality of patient locations on or within a patient; a converter coupled to at least one of the temperature signals that generates a temperature value representative of at least one of the temperatures and a temperature-rate-of-change value based on a rate of temperature change of one of the temperatures; a comparator coupled to the temperature value, the temperature-rate-of-change value, and to the minimum and maximum temperature parameters, and the minimum and maximum temperature-rate-of-change parameters;
in the computer system to generate comparison values;a heat exchanger in fluid communication with the source of physiological fluid; a signal generator controlled by the computer system which generates a control signal that is coupled to the heat exchanger to control a change in the temperature of the physiological fluid based on the comparison values; a fluid pump in fluid communication with the heat exchanger and having a fluid outlet for the physiological fluid, the pump having a pumping rate controlled by the computer system whereby the physiological fluid is pumped to be perfused into the patient after a temperature change has been affected and perfuses the physiological fluid into the patient. - View Dependent Claims (16, 17, 18, 19, 20)
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Specification