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Antisense oligonucleotides targeting cooperating oncogenes

  • US 5,734,039 A
  • Filed: 09/15/1994
  • Issued: 03/31/1998
  • Est. Priority Date: 09/15/1994
  • Status: Expired due to Fees
First Claim
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1. A composition comprising at least one first antisense oligonucleotide specific for a cytoplasmic oncogene or proto-oncogene selected from the group consisting of ras genes, raf genes, EGF-1, c-fms, c-ros, c-kit, c-met, c-trk, c-src, c-abl, bcr-abl, c-fgr and c-yes and at least one second antisense oligonucleotide specific for a nuclear oncogene or proto-oncogene selected from the group consisting of myc genes, jun genes, c-ets, c-fos, c-myb, B-myb, c-rel, c-vav, c-ski, c-spi, cyclin D1, PML/RARα

  • , AML1/MTG8, E2A/prl and ALL-1/AF-4.

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