Ultrasound energy delivery system and method

• US 5,735,280 A
• Filed: 09/09/1996
• Issued: 04/07/1998
• Est. Priority Date: 05/02/1995
• Status: Expired due to Fees

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Heart Rhythm Technologies, Inc.
• Inventors: Sherman, Marshall L., Castellano, Thomas M.
• Primary Examiner(s): Manuel, George
• Application Number:
  US08/708,829
• Time in Patent Office: 575 Days
• Field of Search: 128/660.01, 128/660.02, 128/660.03, 128/660.06, 601/2, 601/3, 607/105, 607/102, 607/113, 607/116, 607/97, 604/22
• US Class Current: 600/1
• CPC Class Codes: A61B 17/2202 the ultrasound transducer being inside patient's body at the distal end of the catheter
• CPC Class Codes: A61B 2017/00084 Temperature
• CPC Class Codes: A61B 2017/00092 using thermocouples
• CPC Class Codes: A61B 2017/00243 cardiac

Abstract

An energy delivery system and method controls the frequency of the power driving an ultrasonic device to achieve more efficient power delivery. During operation of the ultrasonic device to deliver power to a patient site, the system and method automatically sweeps the drive power through a frequency range, locates the series and parallel resonance frequencies, calculates the average of those frequencies and locks the power generator at that average frequency to drive the crystal. This frequency sweep procedure occurs automatically when the ultrasonic crystal is located at the patient site and the power generator operator presses the power-on switch to apply power. The method of tuning the power generator thus occurs when the crystal is at the site temperature and is transparent to the operator. The application of an external bio-layer to the crystal increases its bandwidth and its robustness. Mounting a temperature sensor or sensors at the crystal permits monitoring of the crystal temperature and allows drive level control over the power generator to control the temperature at the crystal.

Claims

1. A system for delivering energy to biological tissue, comprising:

a catheter having distal and proximal ends;

an ultrasonic transducer adapted to transduce electrical energy into acoustic energy, the transducer having a characteristic frequency, the transducer mounted at the distal end of the catheter;

a power supply that provides electrical energy to the ultrasonic transducer at a selectable frequency;

a power transfer sensor coupled to the ultrasonic transducer that measures the response of the ultrasonic transducer to the power provided to it by the power supply, the sensor providing a power transfer signal;

a processor adapted to automatically control the power supply to vary the frequency of electrical energy applied to the transducer and to monitor the power transfer signal in response to the frequency variation to determine the characteristic frequency of the transducer.

2. The system of claim 1 wherein the processor automatically controls the power supply to sweep through a predetermined range of frequencies while monitoring the power transfer signal to determine the characteristic frequency.

3. The system of claim 2 wherein the processor automatically controls the power supply to operate at the determined characteristic frequency.

4. The system of claim 2 wherein the processor is adapted to automatically process the determined characteristic frequency to derive an operation frequency therefrom and automatically control the power supply to operate at the operation frequency.

5. The system of claim 1 wherein the tuning system automatically controls the power supply to sweep through a predetermined range of frequencies while monitoring the power transfer signal to determine first and second resonance frequencies of the ultrasonic transducer.

6. The system of claim 5 wherein the processor automatically controls the power supply to operate at or near one of the determined resonance frequencies.

7. The system of claim 5 wherein the tuning system automatically processes the determined resonance frequencies to derive an operation frequency therefrom and automatically controls the power supply to operate at the operation frequency.

8. The system of claim 7 wherein the processor automatically averages the first and second resonance frequencies and automatically controls the power supply to operate at the average frequency.

9. The system of claim 8 further comprising a power application switch;

wherein the processor is responsive to actuation of the power application switch to automatically control the power supply to apply power to the ultrasonic transducer while varying the frequency to determine the first and second resonant frequencies while monitoring the power transfer signal and to then apply a predetermined level of power as selected at the operation frequency.

10. The system of claim 1 further comprising a biologically-compatible layer formed on the outside of the ultrasonic transducer that lowers the frequency sensitivity of the transducer.

11. The system of claim 10 wherein the biologically-compatible layer is non-metallic and has a relatively high coefficient of thermal conductivity.

12. The system of claim 1 further comprising a temperature sensor mounted at the distal end of the catheter that senses temperature and provides a temperature sensing signal.

13. The system of claim 12 wherein the processor receives the temperature sensing signal, compares it to a predetermined first threshold temperature and controls the power supply to decrease the power drive level when the temperature signal represents a temperature above the first threshold.

14. The system of claim 13 wherein the processor automatically controls the power supply to hold the frequency constant while varying the power level to maintain the temperature within a predetermined range.

15. The system of claim 12 wherein the temperature sensor is mounted in the ultrasonic transducer.

16. The system of claim 15 wherein the ultrasonic transducer is cylindrically shaped.

17. A method of delivering energy to a biological site, comprising the steps of:

locating a catheter having an ultrasonic transducer at the site;

applying electrical power to the ultrasonic transducer that is adapted to transduce electrical energy into acoustic energy, the transducer having a characteristic frequency;

measuring the response of the ultrasonic transducer to the power provided to it, the sensor providing a power transfer signal;

automatically varying the frequency of electrical energy applied to the transducer and monitoring the power transfer signal in response to the frequency variation to determine the characteristic frequency of the transducer.

18. The method of claim 17 wherein the step of varying the frequency comprises the step of automatically sweeping through a predetermined range of frequencies while monitoring the power transfer signal to determine the characteristic frequency.

19. The method of claim 18 comprising the further step of automatically applying power to the transducer to operate at the determined characteristic frequency.

20. The method of claim 18 comprising the further step of automatically processing the determined characteristic frequency to derive an operation frequency therefrom and automatically applying power to the transducer at the derived operation frequency.

21. The method of claim 17 further comprising the step of automatically sweeping through a predetermined range of frequencies while monitoring the power transfer signal to determine first and second resonance frequencies of the ultrasonic transducer.

22. The method of claim 21 comprising the further step of automatically applying power to the transducer at or near one of the determined resonance frequencies.

23. The method of claim 21 comprising the further step of automatically deriving an operation frequency from the determined resonance frequencies and automatically applying power to the transducer to operate at the operation frequency.

24. The method of claim 23 comprising the step of averaging the first and second resonance frequencies and automatically applying power to the transducer to operate at the average frequency.

25. The method of claim 24 further comprising the steps of:

actuating a power application switch;

automatically applying power to the ultrasonic transducer while varying the frequency in response to actuation of the power application switch to determine the first and second resonant frequencies while monitoring the power transfer signal; and

applying a predetermined level of power to the transducer at the operation frequency.

26. The method of claim 17 further comprising the step of forming a biologically-compatible layer on the outside of the ultrasonic transducer that lowers the frequency sensitivity of the transducer.

27. The method of claim 26 wherein the step of forming the biologically-compatible layer comprising forming the layer of a non-metallic material that has a relatively high coefficient of thermal conductivity.

28. The method of claim 17 further comprising the steps of sensing temperature at the distal end of the catheter and providing a temperature sensing signal.

29. The method of claim 28 further comprising the steps of comparing the temperature sensing signal to a predetermined first threshold temperature;

decreasing the power drive level to the transducer when the temperature signal represents a temperature above the first threshold.

30. The method of claim 28 further comprising the step os automatically controlling the frequency to be constant while varying the power level to maintain the temperature within a predetermined range.

31. The method of claim 28 further comprising the step of mounting the temperature sensor in the ultrasonic transducer.

32. The method of claim 31 comprising the step of forming the ultrasonic transducer to be cylindrical in shape.