Techniques of treating neurodegenerative disorders by brain infusion
First Claim
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1. A method of treating a neurodegenerative disorder by means of an implantable pump and a catheter having a discharge portion and having a proximal end coupled to said pump, said method comprising the steps of:
- surgically implanting said catheter so that said discharge portion lies adjacent a predetermined infusion site in a brain; and
operating said pump to discharge a predetermined dosage of at least one drug capable of altering the level of excitation of neurons of said brain through said discharge portion of said catheter into said infusion site, whereby neurodegeneration is prevented and said neurodegenerative disorder is therapeutically treated.
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Abstract
Techniques for infusing drugs into the brain to treat neurodegenerative disorders by an implantable pump and catheter. The drugs are capable of altering the level of excitation of neruons in the brain. A sensor is used to detect an attribute of the nervous system which reflects the hyperexcitation of the nerve cells projecting onto the degenerating nerve cells. A microprocessor algorithm analyzes the output from the sensor in order to regulate the amount of drug delivered to the brain.
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25 Claims
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1. A method of treating a neurodegenerative disorder by means of an implantable pump and a catheter having a discharge portion and having a proximal end coupled to said pump, said method comprising the steps of:
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surgically implanting said catheter so that said discharge portion lies adjacent a predetermined infusion site in a brain; and operating said pump to discharge a predetermined dosage of at least one drug capable of altering the level of excitation of neurons of said brain through said discharge portion of said catheter into said infusion site, whereby neurodegeneration is prevented and said neurodegenerative disorder is therapeutically treated. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25)
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Specification