Apparatus for transsphenoidal stimulation of the pituitary gland and adjoining brain structures

• US 5,735,817 A
• Filed: 05/19/1995
• Issued: 04/07/1998
• Est. Priority Date: 05/19/1995
• Status: Expired due to Term

• Current Assignee: Wedge Therapeutics, LLC
• Original Assignee: T. R. Shantha
• Inventors: Shantha, T. R.
• Primary Examiner(s): Buiz, Michael Powell
• Assistant Examiner(s): NGUYEN, ANH TUAN TUONG
• Application Number:
  US08/445,421
• Time in Patent Office: 1,054 Days
• Field of Search: 604/96, 604/97-100, 604/113, 604/43, 604/21, 606/194, 128/637
• US Class Current: 604/100.02
• CPC Class Codes: A61F 2007/0054 with a closed fluid circuit, e.g. hot water
• CPC Class Codes: A61F 7/123 using a flexible balloon containing the thermal element
• CPC Class Codes: A61M 2210/0693 Brain, cerebrum
• CPC Class Codes: A61M 25/10 Balloon catheters A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02; inflatable balloons for placing stents or stent-grafts A61F2/958 ; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00
• CPC Class Codes: A61M 29/02 Dilators made of swellable material balloon catheters for angioplasty A61M25/104
• CPC Class Codes: A61N 1/36017 with leads or electrodes penetrating the skin
• CPC Class Codes: A61N 1/36021 for treatment of pain

Abstract

A method and apparatus are provided for the stimulation through the sphenoid sinus, the pituitary gland and the adjoining brain structures. The apparatus consists of an inflatable balloon and which is inserted into the sphenoid sinus and inflated. The balloon will stimulate by pressure, heat, cold or electricity, the structures surrounding the sphenoid sinus. The balloon is controlled via connecting tubes and control wires. This method and apparatus has application in the treatment of pain and a number of other maladies of the nervous system.

Claims

1. An apparatus for stimulating the sphenoid sinus and proximate structures of the human body, the apparatus comprising:

an insertion body having a balloon with a flexible outer surface adapted to contact and conform to the interior surface of the sphenoid sinus, the balloon having an interior;

means connected to the interior of the balloon for inflating the balloon while in the sphenoid sinus;

a thermocouple connected to and residing within the interior of the balloon for locally heating and cooling fluid present within the balloon and for locally heating and cooling the interior surface of the sphenoid sinus immediately adjacent the outer surface of the balloon;

a temperature sensor connected to the interior of the balloon and connected to a temperature indicator external to the balloon for monitoring the temperature of the outer surface of the balloon;

electrical stimulators attached to the outer surface of the balloon;

connection means for connecting the electrical stimulators to a power source and control device outside of the sphenoid sinus for stimulating the sphenoid sinus and proximate structures with controlled electric current; and

,

means attached to the outer surface of the balloon for discharging drugs from the insertion body into the interior of the sphenoid sinus for absorption by the pituitary gland or central nervous system.

2. The apparatus of claim 1 which a tube is connected to the balloon for infusing fluid into the interior of the balloon and the apparatus further comprises a device external to the balloon and connected to the balloon for heating and cooling fluid prior to infusion into the interior of the balloon while the balloon is in the sphenoid sinus.

3. The apparatus of claim 2 in which the means for inflating the balloon is at least one tube which is connected to an inflator.