Reinforced microdialysis probe

• US 5,735,832 A
• Filed: 07/31/1996
• Issued: 04/07/1998
• Est. Priority Date: 02/04/1994
• Status: Expired due to Term

• Current Assignee: Cma/Microdialysis Holding AB
• Original Assignee: Cma/Microdialysis Holding AB
• Inventors: Karlsson, Hans
• Primary Examiner(s): Buiz, Michael Powell
• Assistant Examiner(s): Blyveis, Deborah
• Application Number:
  US08/682,746
• Time in Patent Office: 615 Days
• Field of Search: 604/19, 604/27, 604/29, 604/48, 604/95, 604/96, 604/36, 604/93, 604/280, 604/282, 604/264, 128/632
• US Class Current: 604/524
• CPC Class Codes: A61B 10/0045 Devices for taking samples of body liquids devices for taking blood samples A61B5/15
• CPC Class Codes: A61B 5/14528 invasively
• CPC Class Codes: A61M 25/0043 characterised by structural features

Abstract

A microdialysis probe having a center tube surrounded by a thin dialysis tube (3), which is located between two tubular fitting parts (2, 5). With the purpose of reinforcing the probe and facilitating its withdrawal without any part of the probe remaining despite the fragility of the dialysis tube, the distal end of the center tube from within is fixedly joined to the distal fitting part (2), which also has a larger diameter than the dialysis tube (3).

Claims

1. A microdialysis probe, having a distal end comprising:

a center tube having a proximal end, a closed distal end, a side surface, and a distal aperture located in the side surface, said distal end of said center tube having an enlargement;

a semi-permeable mantle tube surrounding said center tube, said mantle tube having a proximal end and a distal end, said mantle tube being free of an external mounting for support thereof, said mantle tube and said center tube defining a space therebetween, said distal aperture opening into the space between the mantle tube and the center tube;

a fitting partially surrounding said mantle tube for supporting and partially exposing said mantle tube, said fitting including a first tube surrounding and fastened to said proximal end of said mantle tube, said fitting including a second tube surrounding and fastened to said distal end of said mantle tube, said second tube having a closed distal end, said enlargement of said center tube being fitted within said second tube.

2. A microdialysis probe according to claim 1, wherein the mantle tube has a wall thickness of 15-50 μ

m.

3. A microdialysis probe according to claim 2, wherein the mantle tube comprises one of polyamide and cellulose.

4. A microdialysis probe according to claim 1, wherein the first and second tubes are plastic.

5. A microdialysis probe according to claim 1, further comprising glue laid between the enlargement of the center tube and the distal end of the second tube, thereby attaching the center tube to said second tube and forming a closure at the distal end of the second tube.

6. A microdialysis probe according to claim 1, wherein the second tube forms an enlargement of the distal end of the probe, this enlargement having a larger outer diameter than the outer diameter of the mantle tube.

7. The microdialysis probe according to claim 1, further comprising a first external connecting pipe connected to the proximal end of said center tube, and a second external connecting pipe communicating with the space between said mantle tube and said center tube.