Anchoring tip assembly for microwave ablation catheter

• US 5,741,249 A
• Filed: 11/25/1996
• Issued: 04/21/1998
• Est. Priority Date: 10/16/1996
• Status: Expired due to Term

• Current Assignee: Maquet Cardiovascular LLC (Getinge AB)
• Original Assignee: Fidus Medical Technology Corporation
• Inventors: Moss, Jon F., Sturzu, Peter, Nguyen, Hiep P.H.
• Primary Examiner(s): Lacyk, John P.
• Assistant Examiner(s): Ruddy, David M.
• Application Number:
  US08/755,998
• Time in Patent Office: 512 Days
• Field of Search: 606/33, 606/41, 607/154, 607/156, 607/119, 607/122, 607/101, 607/126, 607/127, 607/128, 607/100
• US Class Current: 606/33
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 2018/00351 Heart
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00839 Bioelectrical parameters, e.g. ECG, EEG
• CPC Class Codes: A61B 2018/1846 Helical antennas
• CPC Class Codes: A61B 2018/1861 with an instrument inserted into a body lumen or cavity, e.g. a catheter
• CPC Class Codes: A61N 1/06 for high-frequency therapy

Abstract

An ablation catheter with an anchoring tip extension includes an elongated flexible tubular member adapted to be inserted into a vessel in the body of a patient. A transmission line is disposed within the tubular member, and a transducer is coupled to the transmission line for generating an electric field sufficiently strong to cause tissue ablation. An anchoring tip extension, which is located at the distal end of the catheter, lodges into the wall of a cardiac chamber and serves to anchor the catheter both during an ablation procedure and during the process of conforming the catheter to the wall. In one preferred embodiment, the catheter includes a shape memory wire. In another embodiment, the transmission line of the catheter is a co-axial cable, and the transducer is a helical antenna coil that is adapted to radiate electromagnetic energy in the microwave frequency range. Methods for manufacturing and using such ablation catheters are also described.

Claims

1. An ablation catheter comprising:

an elongated flexible tubular member adapted to be inserted into a vessel in the body of a patient, the flexible tubular member including a proximal portion and a distal portion, the distal portion having a first diameter;

a transmission line disposed within the tubular member, the transmission line having proximal and distal ends, wherein the proximal end of the transmission line is suitable for connection to an electromagnetic energy source;

a transducer coupled to the transmission line for generating an electric field sufficiently strong to cause tissue ablation; and

a flexible anchoring tip extension immovably attached to and integrally formed with the distal portion of the catheter, the anchoring tip extension being more flexible than the distal portion of the elongated flexible tubular members wherein the anchoring tip extension is not arranged to penetrate a body wall of the patient during use.

2. An ablation catheter as recited in claim 1 wherein the anchoring tip extension has a diameter that is smaller than the diameter of the distal portion of the elongated flexible tubular member.

3. A catheter as recited in claim 2 further comprising a distal tip portion of the flexible tubular member, wherein the distal tip portion is formed from a silicone material that encapsulates the transducer.

4. A catheter as recited in claim 3 wherein:

the anchoring tip extension is carried by the distal tip portion of the flexible tubular member; and

the anchoring tip extension is formed form the silicone material which forms the distal tip portion.

5. A catheter as recited in claim 1 wherein:

the distal portion of the flexible tubular member has a diameter of at least 0.07 inches;

the anchoring tip extension has a diameter in the range of approximately 0.05 to 0.07 inches; and

the anchoring tip extension has a length in the range of approximately 0.08 to 0.5 inches.

6. A catheter as recited in claim 5 wherein:

the anchoring tip extension has a diameter of approximately 0.06 inches; and

the anchoring tip extension has a length in the range of approximately 0.2 to 0.3 inches.

7. A catheter as recited in claim 1 wherein:

the transmission line is a co-axial cable; and

the transducer is a helical antenna coil that is adapted to radiate electromagnetic energy in the microwave frequency range.

8. A catheter as recited in claim 1 further comprising a shape memory wire positioned within the antenna coil for straightening the distal portion of the elongated flexible tubular member after an ablation operation.

9. An ablation catheter comprising:

an elongated flexible tubular member adapted to be inserted into a vessel in the body of a patient, the flexible tubular member including a proximal portion and a distal portion, the distal portion having a first diameter;

a transmission line disposed within the tubular member, the transmission line having proximal and distal ends, wherein the proximal end of the transmission line is suitable for connection to an electromagnetic energy source;

a transducer coupled to the transmission line for generating an electric field sufficiently strong to cause tissue ablation; and

a flexible anchoring tip extension immovably attached to the distal portion of the catheter, the anchoring tip extension having a diameter that is smaller than the diameter of the distal portion of the elongated flexible tubular member, wherein the anchoring tip extension is not arranged to penetrate a body wall of the patient during use.

10. A catheter as recited in claim 9 wherein:

the distal portion of the flexible tubular member has a diameter of at least 0.07 inches;

the anchoring tip extension has a diameter in the range of approximately 0.05 to 0.07 inches; and

the anchoring tip extension has a length in the range of approximately 0.08 to 0.5 inches.

11. A catheter as recited in claim 10 wherein:

the anchoring tip extension has a diameter of approximately 0.06 inches; and

the anchoring tip extension has a length in the range of approximately 0.2 to 0.3 inches.

12. A catheter as recited in claim 9 wherein the catheter is a microwave ablation catheter.

13. A catheter as recited in claim 12 wherein:

the transmission line is a co-axial cable disposed within the tubular member, the co-axial cable having proximal and distal ends, wherein the proximal end of the co-axial cable is suitable for connection to an electromagnetic energy source; and

the transducer is a helical antenna coil coupled to the co-axial cable for generating an electric field sufficiently strong to cause tissue ablation.

14. A catheter as recited in claim 13 wherein:

the distal portion of the flexible tubular member is formed from a silicone material that encapsulates the helical antenna coil; and

the anchoring tip extension is formed from the silicone material.

15. A catheter as recited in claim 14 wherein:

the helical antenna coil has an outer diameter in the range of approximately 0.07 to 0.1 inches;

the helical antenna coil has a length in the range of approximately 0.2 to 2.5 inches;

the anchoring tip extension has a diameter in the range of approximately 0.05 to 0.07 inches; and

the anchoring tip extension has a length in the range of approximately 0.08 to 0.5 inches.

16. A catheter as recited in claim 15 wherein the microwave ablation catheter is an atrial fibrillation catheter.

17. A catheter as recited in claim 16 further comprising a shape memory wire positioned within the antenna coil wherein the shape memory wire is formed from a material selected from the group consisting of copper beryllium alloys, steel alloys, and nickel titanium.

18. A method for medical treatment using an ablation catheter system that includes a catheter having a transmission line disposed within a flexible tubular member, a transducer coupled to the transmission line at a tip portion of the catheter for generating an electric field sufficiently strong to cause tissue ablation, and a flexible anchoring tip extension immovably attached to and integrally formed with a distal portion of the catheter tip, the anchoring tip extension being more flexible than the tip portion of the catheter, the method comprising the steps of

a) introducing the catheter into a patient'"'"'s body such that the anchoring tip extension is lodged against but does not penetrate a wall of a cardiac chamber;

b) substantially conforming the tip portion of the catheter to the wall of the chamber with the anchoring tip lodged in place;

c) applying electromagnetic energy to the transmission line to cause ablation of cardiac tissue in a region adjacent the tip portion of the catheter;

d) repositioning the catheter tip, wherein during repositioning of the catheter tip the anchoring tip extension is dislodged from the wall of the chamber; and

e) repeating steps (c) and (d) to facilitate the ablation of different regions of cardiac tissue.

19. A method as recited in claim 18 wherein introducing the catheter into a patient'"'"'s body comprises:

monitoring electro-physiological signals using catheter electrodes;

determining an appropriate ablation position based at least in part on the monitored electro-physiological signals; and

positioning the transducer at the determined appropriate ablation position.

20. A method as recited in claim 18 wherein microwave energy is applied to the transmission line to cause the ablation.

21. A method as recited in claim 18 wherein repositioning the catheter involves lodging the anchoring tip extension against the wall of the cardiac chamber.