Sequential medical fluid aspiration and injection system and method

• US 5,743,886 A
• Filed: 08/20/1996
• Issued: 04/28/1998
• Est. Priority Date: 02/15/1994
• Status: Expired due to Term

• Current Assignee: Lawrence A. Lynn
• Original Assignee: Lawrence A. Lynn
• Inventors: Larkin, Mark E., Lynn, Lawrence A.
• Primary Examiner(s): McDermott, Corrine M.
• Assistant Examiner(s): Blyveis, Deborah
• Application Number:
  US08/697,085
• Time in Patent Office: 616 Days
• Field of Search: 604/191, 604/187, 604/89-91, 604/218, 604/238, 604/207-208, 604/122-125, 604/82, 128/760, 128/762
• US Class Current: 604/191
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2037 having valve means
• CPC Class Codes: A61J 1/2055 having gripping means
• CPC Class Codes: A61J 1/2058 having multiple connecting ports
• CPC Class Codes: A61J 1/2062 with directional valves
• CPC Class Codes: A61J 1/2072 for internal venting
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61M 2005/1403 Flushing or purging
• CPC Class Codes: A61M 2005/1787 Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid
• CPC Class Codes: A61M 2005/3104 Caps for syringes without needle
• CPC Class Codes: A61M 2005/3117 Means preventing contamination of the medicament compartment of a syringe
• CPC Class Codes: A61M 2005/3128 Incorporating one-way valves, e.g. pressure-relief or non-return valves
• CPC Class Codes: A61M 2005/3132 having flow passages for injection agents at the distal end of the barrel to bypass a sealing stopper after its displacement to this end due to internal pressure increase
• CPC Class Codes: A61M 2005/31598 having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
• CPC Class Codes: A61M 2005/3223 Means impeding or disabling repositioning of used needles at the syringe nozzle
• CPC Class Codes: A61M 5/002 Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics needle protection, e.g. caps, A61M5/3202; for sharps A61B50/3001
• CPC Class Codes: A61M 5/1782 Devices aiding filling of syringes in situ combination of a vial and a syringe for transferring or mixing their contents A61J1/2096, filling of medical containers in general B65B3/003
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/2429 by telescoping of ampoules or carpules with the syringe body
• CPC Class Codes: A61M 5/31596 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/347 : rotatable, e.g. bayonet or screw A61M5/344 takes precedence

Abstract

A system for the sequential and repetitive aspiration and injection of fluid. The system includes a syringe having an internal volume, a piston to vary the internal volume and a chamber divider for separating the internal volume into proximal and distal reservoirs. The chamber divider is moveable along the chamber and is positioned adjacent the distal end of the chamber prior to withdrawal of fluid into the syringe. The proximal reservoir has a maximum displacement volume for receiving fluid. A flow channel provides flow between the proximal and distal reservoirs and a valve disables and enables flow therethrough. A tensile element links the piston and the chamber divider so that after the piston is moved and the proximal reservoir is filled with a first liquid, the chamber divider is pulled away from the distal end of the syringe to enlarge the distal reservoir and draw the blood into the distal reservoir. A conduit is connected with the syringe and is in communication with the patient'"'"'s blood vessel and contains the first liquid. The flow channel and the conduit are sized and configured such that after the maximum volume of first liquid has been withdrawn into the proximal reservoir and the blood has been withdrawn into the distal reservoir, the maximum volume of first liquid is substantially free from blood, and subsequent displacement of the maximum volume of first liquid back through the valve is sufficient to displace all the blood from the syringe when the piston is advanced.

Claims

1. A syringe for the sequential withdrawal of a first liquid and a second liquid into said syringe and for the subsequent sequential injection of said second liquid and then said first liquid into a patient, the syringe comprising:

a. a barrel having a distal end and an opening in said distal end;

b. a proximal piston moveable along said barrel to define a variable volume chamber intermediate said proximal piston and said distal end;

c. a chamber divider piston for separating said variable volume into primary and secondary reservoirs, said chamber divider piston being moveable along said barrel within said variable volume chamber, said chamber divider piston being positioned adjacent said distal end prior to withdrawal of said first liquid into said syringe;

d. a flow channel along said syringe, said flow channel being capable of providing flow connection between the primary reservoir and the secondary reservoir, said flow channel being in fluid communication with said opening and said secondary reservoir;

e. an element linking said proximal piston and said chamber divider piston so that when said proximal piston is moved away from said chamber divider piston, and said first reservoir is at least partially filled with said first liquid, said chamber divider piston is urged by said element away from said distal end to enlarge said secondary reservoir and to withdraw said second liquid into said secondary reservoir;

wherein said syringe includes a valve, said valve being capable of at least one disabling and enabling flow between said primary reservoir and said secondary reservoir through said flow channel;

wherein said flow channel extends through said divider piston;

wherein said valve comprises a plug carried by said chamber divider piston adjacent said flow channel, said plug being moveable from a first position wherein said flow channel is open to a second position that is a sealing position wherein said flow channel is closed and sealed by said plug.

2. The syringe of claim 1 wherein said valve further includes plug urging means for urging said plug out of said sealing position within said flow channel to allow fluid to flow through said flow channel.

3. The syringe of claim 2 wherein said plug urging means includes contact means for contacting said barrel, and wherein contact between said contact means and said barrel induces said urging means to urge said plug from said sealing position.

4. The syringe of claim 3 wherein said contact means is carried by said chamber piston.

5. The syringe of claim 2 wherein said plug urging means is carried by said chamber divider piston.

6. The syringe of claim 1 wherein the plug is connected to said element, said element connecting said plug to said proximal piston, said plug being moveable by said proximal piston through force transmitted upon said element from said first position wherein said flow channel provides fluid connection between said primary reservoir and said secondary reservoir to said second position wherein said plug occludes said flow channel to isolate said primary reservoir from said secondary reservoir.

7. The syringe of claim 6 wherein said flow channel is positioned centrally within said chamber divider piston.

8. The syringe of claim 1 wherein said flow channel has a main large main bore adjacent said secondary reservoir, said main bore being connected to said primary reservoir by a smaller bore, said smaller bore serving to reduce the transmission of pressure from within said primary reservoir to said plug.

9. The syringe of claim 1 wherein said plug includes longitudinal ribs for engaging said chamber divider piston.

10. A syringe for the sequential withdrawal of a first liquid and a second liquid into said syringe and for the subsequent sequential injection of said second liquid and then said first liquid into a patient, the syringe comprising:

a. a barrel having a distal end and an opening in said distal end;

b. a proximal piston moveable along said barrel to define a variable volume chamber intermediate said proximal piston and said distal end;

c. a chamber divider piston for separating said variable volume into primary and secondary reservoirs, said chamber divider piston being moveable along said barrel within said variable volume chamber, said chamber divider piston being positioned adjacent said distal end prior to withdrawal of said first liquid into said syringe;

d. a flow channel along said syringe, said flow channel being capable of providing flow connection between the primary reservoir and the secondary reservoir, said flow channel being in fluid communication with said opening and said secondary reservoir;

e. an element linking said proximal piston and said chamber divider piston so that when said proximal piston is moved away from said chamber divider piston, and said first reservoir is at least partially filled with said first liquid, said chamber divider piston is urged by said element away from said distal end to enlarge said secondary reservoir and to withdraw said second liquid into said secondary reservoir;

wherein said syringe includes a valve, said valve being capable of at least one disabling and enabling flow between said primary reservoir and said secondary reservoir through said flow channel;

wherein said valve comprises an occluding member and said element comprises a connecting member for connecting said valve to said proximal piston, said connecting member transmitting retraction force from said proximal piston to said chamber divider piston when said primary reservoir has been filled and said proximal piston is retracted, said chamber divider piston being free from substantial retraction force by said connecting member when said primary reservoir is incompletely filled.

11. The syringe of claim 10 wherein said flow channel extends through said chamber divider piston.

12. The syringe of claim 11 wherein said flow channel further includes radially projecting slots for receiving flow from said flow channel, said flow through said slots widely distributing fluid from said primary reservoir over said distal end to provide wide flushing of said distal end.

13. The syringe of claim 12 wherein said radial slots further include circumferential slots for widely distributing said fluid adjacent said distal end to provide wide flushing of said distal end.

14. A syringe for the sequential withdrawal of a first liquid and a second liquid into said syringe and for the subsequent sequential injection of said second liquid and then said first liquid into a patient, the syringe comprising:

a. a barrel having a distal end and an opening in said distal end;

b. a proximal piston moveable along said barrel to define a variable volume chamber intermediate said proximal piston and said distal end;

c. a chamber divider piston for separating said variable volume into primary and secondary reservoirs, said chamber divider piston being moveable along said barrel within said variable volume chamber, said chamber divider piston being positioned adjacent said distal end prior to withdrawal of said first liquid into said syringe;

d. a flow channel along said syringe, said flow channel being capable of providing flow connection between the primary reservoir and the secondary reservoir, said flow channel being in fluid communication with said opening and said secondary reservoir;

e. an element linking said proximal piston and said chamber divider piston so that when said proximal piston is moved away from said chamber divider piston, and said first reservoir is at least partially filled with said first liquid, said chamber divider piston is urged by said element away from said distal end to enlarge said secondary reservoir and to withdraw said second liquid into said secondary reservoir;

wherein said syringe includes a valve, said valve being capable of at least one disabling and enabling flow between said primary reservoir and said secondary reservoir through said flow channel;

wherein said valve comprises a plug having a first end and a second end, said element being connected to said first plug end, said plug further having legs connected to said second plug end, said plug being carried by said chamber divider piston so that said first plug end projects toward said primary reservoir and said second plug end projects toward said secondary reservoir, said element being connected to said proximal piston, said plug being positioned adjacent said flow channel, said element having an extended length, said length being less than the length of said barrel so that when said proximal piston is retracted within said barrel, said element is extended and so that a retraction force is transmitted through said element to retract said plug into sealing contact with said flow channel to prevent the flow of liquid through said flow channel between said primary and secondary reservoirs.

15. The syringe of claim 14 wherein said legs project toward said secondary reservoir adjacent said chamber divider piston such that said legs contact said barrel when said chamber divider piston is maximally advanced within said barrel, said contact transmitting force through said legs to urge said plug out of said sealing contact with said flow channel so that fluid can flow through said flow channel.

16. The syringe of claim 15 wherein said legs can engage said distal end of said barrel, said legs urging said plug from said sealing contact to open said flow channel when said chamber divider piston is advanced to a position adjacent said distal end of said barrel and said legs engage said distal end.

17. The syringe of claim 14 wherein said retracting force further retracts said chamber divider piston away from said distal end after said plug retracts into said sealing contact with said flow channel.

18. The syringe of claim 14 wherein said legs include feet, said feet having a radius and wherein said legs are connected to said plug by a flexure region, said legs defining an axis, said legs pivoting around said axis when said chamber divider piston presses against said legs and when said feet are prevented from further substantial advancement by said barrel, said pivoting of said legs urging said plug out of said sealing position contact with said flow channel to allow fluid communication between said primary reservoir and said opening.

19. A syringe for the sequential withdrawal of a first liquid and a second liquid into said syringe and for the subsequent sequential injection of said second liquid and then said first liquid into a patient, the syringe comprising:

a. a barrel having a distal end and an opening in said distal end;

b. a proximal piston moveable along said barrel to define a variable volume chamber intermediate said proximal piston and said distal end;

c. a chamber divider piston for separating said variable volume into primary and secondary reservoirs, said chamber divider piston being moveable along said barrel within said variable volume chamber, said chamber divider piston being positioned adjacent said distal end prior to withdrawal of said first liquid into said syringe;

d. a flow channel along said syringe, said flow channel being capable of providing flow connection between the primary reservoir and the secondary reservoir, said flow channel being in fluid communication with said opening and said secondary reservoir;

e. an element linking said proximal piston and said chamber divider piston so that when said proximal piston is moved away from said chamber divider piston, and said first reservoir is at least partially filled with said first liquid, said chamber divider piston is urged by said element away from said distal end to enlarge said secondary reservoir and to withdraw said second liquid into said secondary reservoir;

wherein said syringe includes a valve, said valve being capable of at least one disabling and enabling flow between said primary reservoir and said secondary reservoir through said flow channel;

wherein said value is moveable from a closed position, preventing flow between said secondary reservoir and said primary reservoir to an open position, allowing flow through said flow channel between said primary reservoir and said secondary reservoir.

20. The syringe of claim 19 wherein said element moves said valve from said open position to said closed position.