Instrument having ultra-thin conductive coating and method for magnetic resonance imaging of such instrument

• US 5,744,958 A
• Filed: 11/07/1995
• Issued: 04/28/1998
• Est. Priority Date: 11/07/1995
• Status: Expired due to Fees

• Current Assignee: Roger W. Werne
• Original Assignee: ITI Medical Technologies, Inc.
• Inventors: Werne, Roger W.
• Primary Examiner(s): Arana, Louis M.
• Application Number:
  US08/554,446
• Time in Patent Office: 903 Days
• Field of Search: 324/318, 324/322, 324/300, 324/307, 324/321, 324/301, 324/309, 128/653.2-653.5
• US Class Current: 324/318
• CPC Class Codes: A61B 10/02 Instruments for taking cell samples or for biopsy A61B10/0038 and A61B10/0045 take precedence; needle locating or guiding means A61B17/3403; samplers for enzymology or microbiology C12M1/26; sampling or preparing biological specimens G01N33/48
• CPC Class Codes: A61B 10/0275 with sample notch, e.g. on the side of inner stylet
• CPC Class Codes: A61B 17/00 Surgical instruments, devices or methods, e.g. tourniquets A61B18/00 takes precedence; contraceptive devices, pessaries, or applicators therefor A61F6/00; eye surgery A61F9/007; ear surgery A61F11/00
• CPC Class Codes: A61B 17/02 for holding wounds open; Tractors specula A61B1/32 ; drainage appliances for wounds A61M27/00
• CPC Class Codes: A61B 17/122 Clamps or clips , e.g. for the umbilical cord for the vas deferens A61F6/206
• CPC Class Codes: A61B 17/34 Trocars; Puncturing needles pointed biopsy instruments A61B10/0233; devices for piercing the ear-lobes A44C7/001; seals or hemostasis valves A61M39/06
• CPC Class Codes: A61B 2017/00902 transparent or translucent
• CPC Class Codes: A61B 2090/3954 magnetic, e.g. NMR or MRI
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: G01R 33/285 Invasive instruments, e.g. catheters or biopsy needles, specially adapted for tracking, guiding or visualization by NMR

Abstract

A coated instrument for use in a magnetic resonance imaging (MRI) system, a method for designing such an instrument, and an MRI method including the steps of positioning a coated instrument (constructed in accordance with the invention) and a target in the imaging region of an MRI system, and operating the MRI system to produce an image showing both the target and the instrument. The instrument has a non-electrically conductive body covered by an electrically conductive, ultra-thin coating on at least part of the body. The thickness of the coating is determined (preferably experimentally) to be just large enough to cause the instrument to be positively shown in an MR image produced by the MRI system, but not so large as to obscure or distort unacceptably the image of a target (e.g., a typical target, such as human tissue, with which the instrument is to be imaged) in the same MR image (where both the instrument and target are in the MRI system'"'"'s imaging region when the MRI system produces the MR image). The ultra-thin coating actually creates an imaging artifact which is sufficient to cause the instrument to be visible, but not so significant as to unacceptably distort the image of the intended target. In some preferred embodiments, the coating is a metal whose thickness is 2000 Angstroms or less. In other preferred embodiments, the coating is a metal whose thickness is of the same order of magnitude as its skin depth with respect to the radio frequency (RF) of the MRI system'"'"'s RF field.

Claims

1. A magnetic resonance imaging system, including:

an imaging region and a means for generating a magnetic resonance image of a target object in the imaging region, said magnetic resonance image including an image of the target object, wherein the means for generating the magnetic resonance image includes means for producing an RF field having an RF frequency in the imaging region; and

an instrument for use with the target object in the imaging region, said instrument including;

an electrically non-conductive body, sized for use with the target object in the imaging region; and

an electrically conductive, ultra-thin coating on at least part of the body, the coating being sufficiently thick to cause the instrument to be positively shown in the magnetic resonance image in response to presence of the instrument in the imaging region with the target object during generation of the magnetic resonance image, wherein the coating consists of material having a skin depth with respect to said RF frequency and the coating has a thickness less than the skin depth.

2. The system of claim 1, wherein the coating is composed of a non-ferromagnetic metal.

3. The system of claim 1, wherein the coating is composed of a ferromagnetic material.

4. The system of claim 1, wherein the coating has a thickness, and the thickness is sufficiently small to avoid significant degrading of the image of the target object during generation of the magnetic resonance image with the instrument and the target object in the imaging region.

5. The system of claim 1, wherein the coating is a non-ferromagnetic metal having a thickness at least substantially equal to 2000 Angstroms.

6. The system of claim 1, wherein the coating covers substantially all of the body.

7. The system of claim 6, wherein the coating is composed of a non-ferromagnetic metal.

8. The system of claim 6, wherein the coating is composed of a ferromagnetic material.

9. The system of claim 6, wherein the coating has a thickness, and the thickness is sufficiently small to avoid significant degrading of the image of the target object during generation of the magnetic resonance image with the instrument and the target object in the imaging region.

10. The system of claim 6, wherein the coating is a non-ferromagnetic metal having a thickness at least substantially equal to 2000 Angstroms.

11. The system of claim 1, wherein the coating covers only a portion or feature of the instrument.

12. The system of claim 1, wherein the coating covers a patterned region of the body.

13. A method for operating a magnetic resonance imaging system, wherein the system includes an imaging region and a means for producing a magnetic resonance image of a target object in the imaging region, said magnetic resonance image including a representation of the target object, wherein the means for generating the magnetic resonance image includes a means for producing an RF field having an RF frequency in the imaging region, said method including the steps of:

(a) positioning an instrument adjacent to or within said target object in the imaging region, where the instrument has a non-electrically conductive body and an electrically conductive, ultra-thin coating on at least part of the body, wherein the coating consists of material having a skin depth with respect to the RF frequency, and the coating has a thickness less than the skin depth; and

(b) operating the system to produce a magnetic resonance image showing both the target object and the coated instrument.

14. The method of claim 13, wherein the magnetic resonance image includes a positively shown representation of the instrument.

15. The method of claim 14, wherein the positively shown representation of the instrument does not significantly degrade the representation of the target object.

16. A method for determining an optimal coating thickness for an instrument for use with a magnetic resonance imaging system, wherein the system includes an imaging region and a means for producing a magnetic resonance image of a target object in the imaging region, and wherein the instrument has an electrically non-conductive body and an electrically conductive coating on at least part of the body, the method including the steps of:

(a) positioning a test instrument in the imaging region, said test instrument having an electrically non-conductive test body substantially identical to the electrically non-conductive body, and a test coating of electrically conductive material having a first test thickness on at least part of the test body;

(b) operating the system to produce a test magnetic resonance image showing the test instrument;

(c) positioning at least one additional test instrument in the imaging region, wherein each said additional test instrument has an electrically non-conductive test body substantially identical to the electrically non-conductive body, wherein at least a portion of the test body of each said additional test instrument is coated with a different thickness of said electrically conductive material, wherein each said different thickness differs from the first test thickness, and wherein said first test thickness and each said different thickness together comprise a set of test thicknesses, and said test instrument and said at least one additional test instrument together comprise a set of test instruments;

(d) operating the system to produce at least one additional test magnetic resonance image showing each said additional test instrument, wherein said at least one additional test magnetic resonance image and said test magnetic resonance image together comprise a set of test images; and

(e) identifying as the optimal coating thickness, the test thickness which results in a test image having a desired positively shown representation of one of the test instruments.

17. The method of claim 16, wherein the target object is positioned in the imaging region with the test instrument during each of steps (a)-(d), wherein each of the test images includes a representation of the target object, and wherein said desired positively shown representation of one of the test instruments does not significantly degrade the representation of the target object.