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Suspension of loteprednol etabonate for ear, eye, or nose treatment

  • US 5,747,061 A
  • Filed: 07/29/1996
  • Issued: 05/05/1998
  • Est. Priority Date: 10/25/1993
  • Status: Expired due to Term
First Claim
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1. A composition for ophthalmic or otolaryngological anti-inflammatory use comprising:

  • (A) a corticosteroid in an amount of 0.01 to about 2% by weight and having a particle size of about 0.1 to 30 microns in diameter to substantially prevent discomfort upon use of the composition for said ophthalmic or otolaryngological anti-inflammatory treatment;

    (B) a nonionic polymer in an aqueous medium;

    (C) a nonionic tonicity agent in an amount sufficient to achieve isotonicity; and

    (D) a nonionic surface active agent in an amount sufficient to retain the corticosteroid, the nonionic tonicity agent and the nonionic polymer in a suspension.

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