Implantable medical device responsive to heart rate variability analysis

• US 5,749,900 A
• Filed: 12/11/1995
• Issued: 05/12/1998
• Est. Priority Date: 12/11/1995
• Status: Expired due to Term

• Current Assignee: Intermedics Incorporated
• Original Assignee: Sulzer Intermedics, Inc. (Sulzer AG)
• Inventors: Schroeppel, Edward A., Prutchi, David, Routh, Andre G.
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US08/570,727
• Time in Patent Office: 883 Days
• Field of Search: 607/4, 607/5, 607/6, 607/17, 607/25
• US Class Current: 607/4
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/36585 controlled by two or more physical parameters
• CPC Class Codes: A61N 1/36592 controlled by the heart rate variability
• CPC Class Codes: A61N 1/3962 in combination with another heart therapy
• CPC Class Codes: A61N 1/39622 Pacing therapy

Abstract

A method and apparatus for evaluating heart rate variability of the heart of a person in order to forecast a cardiac event. A cardiac stimulator receives heart beat signals from the heart and determines a measurement of heart rate variability based on statistical data derived from the heart beat signals and sensing data derived from a sensor. This measurement of heart rate variability is compared with previously stored heart rate variability zones defining normal and abnormal heart rate variability. These zones are modifiable after the occurrence of a cardiac event. Once a cardiac event is detected, a pathway is computed which extends from a generally normal heart rate variability condition to an abnormal heart rate variability condition. Subsequent measurements of heart rate variability are compared with this pathway. Selective therapy regimes are initiated depending on the measurement of heart rate variability.

Claims

1. A medical device, comprising:

an electrode for detecting a series of heart beat signals from the heart of a patient;

means for providing a therapy regime to a heart of a patient;

memory having stored therein at least one heart rate variability zone with a corresponding therapy regime; and

control circuitry in electrical communication with said electrode, said control circuitry having

means for receiving said series of heart beat signals and for computing a measurement of heart rate variability,

means for comparing said measurement of heart rate variability to said heart rate variability zone,

means for initiating said therapy regime if said heart rate variability zone includes said measurement of heart rate variability,

means for modifying said heart rate variability zone if said heart rate variability zone does not include said measurement of heart rate variability and said control circuitry detects a cardiac anomaly, and

means for storing said modified heart rate variability zone in said memory.

2. The medical device of claim 1 in which said heart rate variability zone is an abnormal heart rate variability zone and said medical device further comprises means for predicting a cardiac anomaly when said measurement of heart rate variability falls within said abnormal heart rate variability zone.

3. The medical device of claim 1 in which:

said heart rate variability zone includes an abnormal zone defining abnormal heart rate variability and a normal zone defining normal heart rate variability; and

further comprising means for disabling selected computational and diagnostic activities occurring within said control circuitry while said measurement of heart rate variability is within said normal zone.

4. The medical device of claim 1 in which said means for initiating said therapy regime includes at least one of a sensor, a stimulus generator, a defibrillator, neural stimulation, or drug infusion.

5. The medical device of claim 1 in which:

said heart rate variability zone includes an abnormal zone defining abnormal heart rate variability conditions for the heart of said patient and a normal zone defining normal heart rate variability conditions for the heart of said patient; and

said means for initiating therapy includes means for initiating said therapy if said measurement of heart rate variability occurs within said abnormal zone.