Method and apparatus for therapeutic electromagnetic treatment

• US 5,755,751 A
• Filed: 06/07/1995
• Issued: 05/26/1998
• Est. Priority Date: 10/20/1992
• Status: Expired due to Term

• Current Assignee: Lumenis Limited (Boston Scientific Corporation)
• Original Assignee: ESC Medical Systems, Ltd (Boston Scientific Corporation)
• Inventors: Eckhouse, Shimon
• Primary Examiner(s): Bahr, Jennifer
• Assistant Examiner(s): WINAKUR, ERIC FRANK
• Application Number:
  US08/473,532
• Time in Patent Office: 1,084 Days
• Field of Search: 607/88, 607/89, 607/90, 607/91, 607/92, 607/93, 607/54, 606/2, 606/3, 606/9, 606/10, 606/11, 606/12, 606/13, 606/17, 606/18, 606/19
• US Class Current: 607/88
• CPC Class Codes: A61B 18/203 applying laser energy to the outside of the body
• CPC Class Codes: A61B 2017/00057 Light
• CPC Class Codes: A61B 2017/00172 Pulse trains, bursts, intermittent continuous operation
• CPC Class Codes: A61B 2018/00011 with fluids
• CPC Class Codes: A61B 2018/00029 open
• CPC Class Codes: A61B 2018/00452 Skin
• CPC Class Codes: A61B 2018/1807 using light other than laser radiation
• CPC Class Codes: H05B 41/34 to provide a sequence of flashes

Abstract

A therapeutic treatment method includes the steps of providing a pulsed incoherent light output for treatment, directing the pulsed light output to a treatment area, transmitting the pulsed light output through the epidermis at the treatment area, heating the epidermis to a temperature below the temperature at which the epidermis is damaged, and coagulating blood in blood vessels disposed below the epidermis.

Claims

1. A method for coagulating blood in a blood vessel lying below an epidermal layer, comprising the steps of:

generating a pulse of electromagnetic energy;

varying the wavelength of electromagnetic energy;

applying the pulse to the epidermal layer at a rate and for a time insufficient to heat the epidermal layer to a first temperature at which the epidermal layer is damaged, and sufficient to heat the blood vessel to a second temperature greater than the first temperature;

controlling a delay between the pulse and a subsequent pulse of electromagnetic energy; and

coagulating blood in the blood vessel.

2. The method of claim 1 wherein the step of applying the pulse to the epidermal layer includes a step of applying electromagnetic energy in the range of 300 to 1000 nanometers wavelength to the epidermal layer.

3. The method of claim 2 wherein the step of applying the pulse to the epidermal layer includes a step of applying electromagnetic energy having wavelengths in the range of 520 to 650 nanometers, and wherein the blood vessel is an artery having a diameter of less than 0.1 millimeters.

4. The method of claim 2 wherein the step of applying the pulse to the epidermal layer includes a step of applying electromagnetic energy having wavelengths in the range of 520 to 700 nanometers, and wherein the blood vessel is a vein with a diameter of less than 0.1 millimeters.

5. The method of claim 2 wherein the step of applying the pulse to the epidermal layer includes a step of applying electromagnetic energy having wavelengths in the range of 550 to 1000 nanometers, and wherein the blood vessel has a diameter of between 0.1 and 1.0 millimeters.

6. The method of claim 2, wherein the step of applying the pulse to the epidermal layer includes a step of applying electromagnetic energy having wavelengths in the range of 600 to 1000 nanometers, and wherein the blood vessel has a diameter of more than 1.0 millimeters.

7. The method of claim 2, wherein the step of applying the pulse to the epidermal layer includes a step of applying the pulse to an epidermal surface area of at least 0.3 square centimeters.

8. The method of claim 2, wherein the step of applying the pulse to an epidermal surface area includes a step of applying a first pulse to a substantially rectangular epidermal surface area.

9. The method of claim 2, wherein the step of applying the pulse to the epidermal layer includes the step of applying a pulse having an energy fluence of between 6 and 300 J/cm².

10. The method of claim 9, wherein the step of applying the pulse to the epidermal layer includes the step of applying a pulse having an energy fluence of between 6 and 20 J/cm².

11. The method of claim 9, further comprising the step of providing a gel on the epidermal layer and wherein the step of applying the pulse to the epidermal layer includes the step of applying a pulse having an energy fluence of between 30 and 50 J/cm².

12. The method of claim 9, wherein the step of applying the pulse to the epidermal layer includes the step of applying the pulse having an energy fluence of between 30 and 100 J/cm².

13. The method of claim 7, wherein the step of applying the pulse to the epidermal layer includes the step of applying a pulse having a duration of between 5 microseconds and 100 milliseconds.

14. The method of claim 13, wherein the step of applying the pulse to the epidermal layer includes the step of applying a pulse having a duration of between 1 and 20 milliseconds, and wherein the blood vessel has a diameter of less than 0.1 millimeters.

15. The method as recited in claim 1, wherein the step of generating a pulse of electromagnetic energy includes a step of pulsing a flashlamp.

16. The method as recited in claim 15, wherein the step of varying the wavelength includes a step of controlling a current density provided to the flashlamp.

17. The method as recited in claim 15, wherein the step of varying the wavelength includes a step of varying a capacitance coupled to the flashlamp.

18. The method as recited in claim 15, wherein the step of varying the wavelength includes a plurality of filters disposed between the flashlamp and the epidermal layer, the plurality of filters including a reflective filter located proximate the flashlamp and an absorption filter.

19. A method for coagulating blood in a blood vessel lying below an epidermal layer, comprising the steps of:

generating a pulse of electromagnetic energy;

applying the pulse to the epidermal layer at a rate and for a time insufficient to heat the epidermal layer to a temperature at which the epidermal layer is damaged and sufficient to heat the blood vessel;

pausing while the epidermis cools below the temperature achieved in the applying step;

repeating the steps of generating, applying and pausing until the blood in the blood vessel is heated and coagulated.

20. The method of claim 19 wherein the step of applying the pulse to the epidermal layer includes a step of applying electromagnetic energy in the range of 300 to 1000 nanometers wavelength to the epidermal layer.

21. The method of claim 20 wherein the step of applying the pulse to the epidermal layer includes a step of applying electromagnetic energy having wavelengths in the range of 520 to 650 nanometers, and wherein the blood vessel is an artery having a diameter of less than 0.1 millimeters.

22. The method of claim 20 wherein the step of applying the pulse to the epidermal layer includes a step of applying electromagnetic energy having wavelengths in the range of 520 to 700 nanometers, and wherein the blood vessel is a vein with a diameter of less than 0.1 millimeters.

23. The method of claim 20 wherein the step of applying the pulse to the epidermal layer includes a step of applying electromagnetic energy having wavelengths in the range of 550 to 1000 nanometers, and wherein the blood vessel has a diameter of between 0.1 and 1.0 millimeters.

24. The method of claim 20, wherein the step of applying the pulse to the epidermal layer includes a step of applying electromagnetic energy having wavelengths in the range of 600 to 1000 nanometers, and wherein the blood vessel has a diameter of more than 1.0 millimeters.

25. The method of claim 20, wherein the step of applying the pulse to the epidermal layer includes a step of applying electromagnetic energy having wavelengths in the range of 700 to 1000 nanometers, and wherein the step of pausing includes the step of pausing for between 10 and 50 milliseconds.

26. The method of claim 20, wherein the step of applying the pulse to the epidermal layer includes a step of applying the pulse to an epidermal surface area of at least 0.3 square centimeters.

27. The method of claim 20, wherein the step of applying the pulse to an epidermal surface area includes a step of applying a first pulse to a substantially rectangular epidermal surface area.

28. The method of claim 20, wherein the step of applying the pulse to the epidermal layer includes a step of applying a pulse having a first spectral energy distribution and wherein a subsequent step of applying the pulse includes the step of applying a pulse having a second spectrum different from the first spectrum.

29. The method of claim 28, wherein the step of applying a pulse having a second spectrum different from the first spectrum includes the step of applying a pulse having a second spectrum having a longer wavelength range than the first spectrum.

30. The method of claim 28, wherein the step of generating includes the step of conducting a first current through a plasma discharge radiation source, and wherein a subsequent step of generating includes the step of conducting a second current having a magnitude different from the magnitude of the first current through a plasma discharge device.

31. The method of claim 20, wherein the step of applying the pulse to the epidermal layer includes the step of applying a pulse having an energy fluence of between 6 and 300 J/cm².

32. The method of claim 31, wherein the step of applying the pulse to the epidermal layer includes the step of applying a pulse having an energy fluence of between 6 and 20 J/cm².

33. The method of claim 31, further comprising the step of providing a gel on the epidermal layer and wherein the step of applying the pulse to the epidermal layer includes the step of applying a pulse having an energy fluence of between 30 and 50 J/cm².

34. The method of claim 31, wherein the step of applying the pulse to the epidermal layer includes the step of applying the pulse having an energy fluence of between 30 and 100 J/cm².

35. The method of claim 31, wherein the step of applying the pulse to the epidermal layer includes the step of applying a pulse having a duration of between 5 microseconds and 100 milliseconds.

36. The method of claim 35, wherein the step of pausing includes the step of pausing for between 10 and 500 milliseconds.

37. The method of claim 35, wherein the step of applying the pulse to the epidermal layer includes the step of applying a pulse having a duration of between 1 and 20 milliseconds, and wherein the blood vessel has a diameter of less than 0.1 millimeters.

38. The method of claim 35, wherein the step of pausing includes the step of pausing for between 100 and 500 milliseconds, and wherein the blood vessel has a diameter of greater than 1 millimeter in diameter.

39. The method of claim 35, wherein the step of pausing includes the step of pausing for between 20 and 100 milliseconds, and wherein the vessel has a diameter of between 0.5 and 1 millimeter in diameter.

40. The method of claim 35, wherein the step of pausing includes the step of pausing for between 10 and 50 milliseconds, and wherein the blood vessel has a diameter of between 0.1 and 0.5 millimeters.