ECG P QRS T onset and peak detection method

• US 5,758,654 A
• Filed: 04/30/1997
• Issued: 06/02/1998
• Est. Priority Date: 08/29/1996
• Status: Expired due to Fees

• Current Assignee: Harley Street Software Ltd.
• Original Assignee: Harley Street Software Ltd.
• Inventors: Illner, Reinhard, Steacy, Robert Clifford Bruce, Burton-Krahn, Noel Morgen
• Primary Examiner(s): Jastrzab, Jeffrey R.
• Application Number:
  US08/846,348
• Time in Patent Office: 398 Days
• Field of Search: 128/696, 128/702-704, 128/708
• US Class Current: 600/517
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/7239 using differentiation including higher order derivatives

Abstract

A method and apparatus for detecting P or T waves in an electrocardiogram signal in intervals before and after each (previously) detected QRS wave. Within each interval, a candidate pair of samples are selected. If the candidate pair are separated by a time duration which does not exceed a predefined time duration then that pair is rejected and the process repeats. Otherwise, the area "A" of a closed polygon bounded by all of the samples between and including the candidate pair is derived (the polygon'"'"'s base line extends linearly a distance "d" between the candidate pair of sample intervals). The maximum vertical displacement "h" between the base line and any portion of the polygon above the base line is derived. If "h" does not exceed a predefined minimum vertical displacement, then the candidate pair is rejected and the process repeats. Otherwise, a value Gamma=A*h/d is derived for the candidate pair. If Gamma does not exceed any value of Gamma derived previously in respect of any previously selected candidate pair, then the candidate pair is rejected and the process repeats. Otherwise, a value BestGamma is set equal to the candidate pair'"'"'s value Gamma. Another candidate pair is then selected and the process repeats. The P or T wave is selected as that whose value Gamma equals the value BestGamma.

Claims

1. A method of detecting P and T waves in an electrocardiogram signal containing said P and T waves and containing previously detected QRS waves, said method comprising the steps of:

a. selecting a next one of said previously detected QRS waves;

b. defining a first time interval within said electrocardiogram signal, said first time interval preceding said selected QRS wave and containing a plurality of samples of said electrocardiogram signal;

c. defining a second time interval within said electrocardiogram signal, said second time interval following said selected QRS wave and containing a plurality of samples of said electrocardiogram signal;

d. narrowing said first time interval to exclude QRS and previously detected T waves preceding said selected QRS wave;

e. narrowing said second time interval to exclude QRS waves following said selected QRS wave;

f. for each pair of said samples in said first time interval;

i. proceeding to step 1(f)(iv) if said pair of samples are separated by a time duration which does not exceed a predefined time duration;

ii. deriving the area, width, and height of a closed polygon having vertices defined by all samples within said first time interval between and including said pair of samples;

iii. deriving a rating for said polygon as a function of said area, width and height;

iv. selecting another pair of said samples and proceeding to step 1(f)(i);

g. selecting as said P wave that one of said step 1(f) (iii) polygons for which said rating is maximal;

h. for each pair of said samples in said second time interval;

i. proceeding to step 1(h)(iv) if said pair of samples are separated by a time duration which does not exceed a predefined time duration;

ii. deriving the area, width, and height of a closed polygon having vertices defined by all samples within said second time interval between and including said pair of samples;

iii. deriving a rating for said polygon as a function of said area, width and height;

iv. selecting another pair of said samples and proceeding to step 1(h)(i); and

,

i. selecting as said T wave that one of said step 1(h) (iii) polygons for which said rating is maximal.

2. A method as defined in claim 1, further comprising, before said step 1(f), the further step of filtering those portions of said electrocardiogram signal containing said first and second time intervals to remove noise.

3. A method as defined in claim 1, wherein said previously detected QRS waves are respectively characterized by onset, offset and peak values, said method further comprising detecting said onset, offset and peak values by:

a. deriving first and second derivative approximations of said electrocardiogram signal;

b. deriving from said previously detected QRS waves a plurality of threshold values which collectively characterize acceptable bounds for said onset, offset and peak values;

c. for each of said previously detected QRS waves, selecting candidate values for said onset, offset and peak values;

d. comparing said candidate values to said threshold values to derive a measure of difference therebetween;

e. accepting said candidate values as said onset, offset and peak values respectively if said difference does not exceed a predefined minimum;

f. if said difference exceeds said predefined minimum, increasing said respective threshold values and proceeding to said step 3(c).

4. A method as defined in claim 1, wherein said steps 1(f)(ii) and 1(h)r(ii) each further comprise:

a. deriving said closed polygon area as that area bounded by all of said samples between and including said pair of samples, said polygon having a base line extending linearly a distance "d" between said pair of samples;

b. deriving a maxim um vertical displacement "h" between said base line and any portion of said polygon above said base line; and

,

c. comparing said maximum vertical displacement to a predefined minimum vertical displacement; and

,

d. if said maximum vertical displacement exceeds said predefined minimum vertical displacement then defining said rating=A*h/d for said pair of samples.

5. A method as defined in claim 1, wherein:

a. said narrowing step 1(d) further comprises;

i. if said first time interval overlaps a time interval occupied by a previously detected T wave portion of said electrocardiogram signal preceding said first time interval, reducing said first time interval to exclude said previously detected T wave portion;

ii. if said first time interval overlaps a time interval occupied by a previously detected QRS wave portion of said electrocardiogram signal preceding said first time interval, reducing said first time interval to exclude said previously detected QRS wave portion; and

,

b. said narrowing step 1(e) further comprises;

i. if said second time interval overlaps a time interval occupied by a previously detected QRS wave portion of said electrocardiogram signal following said second time interval, reducing said second time interval to exclude said previously detected QRS wave portion.

6. A method as defined in claim 1, wherein said previously detected QRS waves are detected by, for each pair of samples within said respective first and second time intervals:

a. deriving first and second derivative approximations of said electrocardiogram signal;

b. comparing said second derivative approximations and selecting as a first peak that one of said samples for which said second derivative approximation is greatest;

c. proceeding to step 6(q) if said first peak second derivative approximation does not exceed a predefined minimum second derivative approximation value;

d. comparing said second derivative approximations for said samples immediately preceding said first peak and selecting as a second peak that one of said preceding samples for which said second derivative approximation is greatest;

e. comparing said second derivative approximations for said samples immediately following said first peak and selecting as a third peak that one of said following samples for which said second derivative approximation is greatest;

f. proceeding to step 6(q) if said second and third peaks are separated by a time duration which exceeds a predefined maximum onset-offset time duration;

g. proceeding to step 6(q) if the difference between said first and second peak second derivative approximations does not exceed a predefined minimum peak separation value or if the difference between said first and third peak second derivative approximations does not exceed said predefined minimum peak separation value;

h. defining a first threshold D1L as a function of said first derivative approximations for said samples between said first and second peaks;

i. defining a second threshold D1R as a function of said first derivative approximations for said samples between said first and third peaks;

j. defining a third threshold D2LR as a function of said second derivative approximations for said samples between said first and third peaks;

k. selecting as a QRSOn value that one of said samples for which said first and second derivative approximations respectively do not exceed said D1L and D2LR thresholds;

l. selecting as a QRSOff value that one of said samples for which said first and second derivative approximations respectively do not exceed said D1R and D2LR thresholds;

m. proceeding to step 6(q) if said selected QRSOn and QRSOff values are separated by a time duration which does not exceed a predefined QRS time duration;

n. if said selected QRSOn and QRSOff values are separated by a time duration which exceeds said predefined QRS time duration then selecting said second peak as said QRSOn value and selecting said third peak as said QRSOff value;

o. proceeding to step 6(q) if the average values of;

i. said samples between said first peak and said QRSOn value;

ii. said samples between said first peak and said QRSOff value;

do not exceed a predefined average value;

p. if said first peak is not separated from said first peak of an immediately preceding, previously detected QRS wave then rejecting that one of said samples for which said second derivative approximation is lowest; and

,

q. selecting a next pair of said samples and repeating steps 6(a) through 6(p) until none of said samples remain.