Method and apparatus for laser-controlled proton beam radiology

• US 5,760,395 A
• Filed: 04/18/1996
• Issued: 06/02/1998
• Est. Priority Date: 04/18/1996
• Status: Expired due to Fees

• Current Assignee: Fermi Research Alliance, LLC
• Original Assignee: Universities Research Association Incorporated
• Inventors: Johnstone, Carol J.
• Primary Examiner(s): ANDERSON, BRUCE C
• Application Number:
  US08/634,242
• Time in Patent Office: 775 Days
• Field of Search: 250/251, 250/423 P, 250/492.3, 250/306
• US Class Current: 850/62
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 5/10 X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy A61N5/01 takes precedence
• CPC Class Codes: G21K 1/003 Manipulation of charged particles by using radiation pressure, e.g. optical levitation acceleration of charged particles H05H5/00, H05H7/00, H05H9/00, H05H11/00, H05H13/00
• CPC Class Codes: H05H 3/02 Molecular or atomic beam generation charge exchange devices G21K1/14; polarising devices G21K1/16; using resonance or molecular beams for analysing or investigating materials G01N24/002; atomic clock G04F5/14; beam masers H01S1/06

Abstract

A proton beam radiology system provides cancer treatment and proton radiography. The system includes an accelerator for producing an H^- beam and a laser source for generating a laser beam. A photodetachment module is located proximate the periphery of the accelerator. The photodetachment module combines the H^- beam and laser beam to produce a neutral beam therefrom within a subsection of the H^- beam. The photodetachment module emits the neutral beam along a trajectory defined by the laser beam. The photodetachment module includes a stripping foil which forms a proton beam from the neutral beam. The proton beam is delivered to a conveyance segment which transports the proton beam to a patient treatment station. The photodetachment module further includes a laser scanner which moves the laser beam along a path transverse to the cross-section of the H^- beam in order to form the neutral beam in subsections of the H^- beam. As the scanning laser moves across the H^- beam, it similarly varies the trajectory of the proton beam emitted from the photodetachment module and in turn varies the target location of the proton beam upon the patient. Intensity modulation of the proton beam can also be achieved by controlling the output of the laser.

Claims

1. A proton beam radiology system comprising:

an accelerator for accelerating H^- ions to a desired energy level to produce an H^- beam having a first cross-sectional area;

a laser source for generating a scanning laser beam;

a photodetachment module, located proximate to and extending along a predefined peripheral portion of said accelerator, for projecting said scanning laser beam onto a subsection of said cross-sectional area of said H^- beam within a photodetachment region of said H^- beam, said scanning laser beam causing photodetachment within said subsection to form a neutral beam in said subsection of said cross-sectional area, said photodetachment module producing a proton beam from said neutral beam, said photodetachment module emitting said proton beam along an extraction trajectory corresponding to a position of said neutral beam within said H^- beam;

a conveyance segment for transporting said proton beam along a trajectory to a patient treatment facility which delivers said proton beam to a target location upon a patient; and

a laser scanner, operative with said photodetachment module, for moving said scanning laser beam along a transverse scanning pattern within said H^- beam, in order to adjust said extraction trajectory of said proton beam and to vary correspondingly a target location of said proton beam at said patient treatment facility.

2. A proton beam radiology system according to claim 1, wherein said scanner maintains said scanning laser beam parallel to said H^- beam throughout said photodetachment region.

3. A proton beam radiology system according to claim 1, wherein said photodetachment module comprises a stripping foil, located proximate a downstream end thereof, said stripping foil receiving and converting said neutral beam to said proton beam.

4. A proton beam radiology system according to claim 1, wherein said conveyance segment comprises at least one static magnet to transport said proton beam along one of a fixed set of predefined trajectories based on said extraction trajectory of said proton beam from said photodetachment module, said static magnet delivering said proton beam along a fixed trajectory to deliver said proton beam to a corresponding target location.

5. A proton beam radiology system according to claim 1, further comprising a stripping foil having a reflective coating thereon, said foil being aligned along an axis of said H^- beam within said photodetachment module, said coating reflecting said scanning laser beam in a reverse direction, said stripping foil stripping said neutral beam to produce a proton beam.

6. A proton beam radiology system according to claim 1, wherein said scanner comprises a pockel cell array of electro-optic elements aligned to receive said laser beam from said laser source, said scanner individually and selectively turning on and off said elements of said pockel cell array to emit said scanning laser beam in a raster pattern which traverses said H^- beam.

7. A proton beam radiology system according to claim 1, wherein said scanner comprises a turning mirror for guiding said scanning laser beam along a raster pattern across said H^- beam.

8. A proton beam radiology system according to claim 1, wherein said photodetachment module directs said scanning laser beam in a direction opposite to a direction of travel of said H^- beam to induce head-on collisions therebetween within said subsection to provide photodetachment and to form said neutral beam.

9. A proton beam radiology system according to claim 1, wherein said photodetachment module comprises a bending magnet, proximate a downstream end thereof for redirecting said H^- beam along a transfer path about a periphery of said accelerator without interfering with a trajectory of said neutral beam extending along an axis defined by said scanning laser beam.

10. A proton beam radiology system according to claim 1, wherein said photodetachment module aligns said laser beam and said H^- beam along parallel axes and in substantially close proximity to one another.

11. A proton beam radiology method comprising the steps of:

producing an H^- beam having a desired energy level and a first cross-sectional area;

generating a scanning laser beam;

projecting said scanning laser beam onto a subsection of said cross-sectional area of said H^- beam, said scanning laser beam causing photodetachment within said subsection to form a neutral beam therein;

producing a proton beam from said neutral beam, said proton beam extending along an extraction trajectory corresponding to a position of said neutral beam within said H^- beam;

transporting said proton beam along a trajectory to a patient treatment station and delivering said proton beam to a target location upon a patient;

moving said scanning laser beam along a scanning pattern within said H^- beam, in order to adjust said extraction trajectory of said proton beam and to vary correspondingly said target location of said proton beam at said patient station.

12. A proton beam radiology method according to claim 11, further comprising the step of maintaining said scanning laser beam parallel to said H^- beam throughout a photodetachment region of said H^- beam.

13. A proton radiology method according to claim 11, further comprising the step of stripping electrons from said neutral beam to form said proton beam.

14. A radiology method according to claim 11, wherein said transporting step comprises the substep of defining a fixed set of predefined trajectories along which said proton beam will pass, and conveying said proton beam along one of said fixed trajectories based upon an incoming trajectory of said proton beam, and delivering said proton beam to a corresponding target location.

15. A proton beam radiology method according to claim 11, further comprising the step of reflecting said laser beam at a downstream end of a photodetachment region in a reverse direction back upon itself and said subsection of said cross-sectional area of said H^- beam.

16. A proton beam radiology method according to claim 11, further comprising the step of individually and selectively turning off and on separate elements of a pockel cell array to emit said scanning laser beam therefrom in a raster pattern which traverses said H^- beam.

17. A proton beam radiology method according to claim 11, further comprising the step of interposing a turning mirror for guiding said scanning laser beam along a raster pattern across said cross-sectional area of said H^- beam.

18. A proton beam radiology method according to claim 11, further comprising the step of directing said scanning beam in a direction opposite to a direction of travel of said H^- beam to induce head-on collisions therebetween within said subsection to produce photodetachment and form said neutral beam.

19. A proton beam radiology system according to claim 11, further comprising the step of redirecting said H^- beam along a transfer path about a periphery of an accelerator without interfering with a trajectory of said neutral beam, said trajectory of said neutral beam extending along an axis defined by said scanning laser beam.

20. A proton beam radiology method according to claim 11, further comprising the step of aligning said scanning laser beam and said H^- beam along parallel axes aligned substantially close to one another.