Multifaceted ultrasound transducer probe system and methods for its use

• US 5,762,066 A
• Filed: 05/22/1995
• Issued: 06/09/1998
• Est. Priority Date: 02/21/1992
• Status: Expired due to Term

• Current Assignee: THS International, Inc. (Takai Hospital Supply Co., Ltd.)
• Original Assignee: THS International, Inc. (Takai Hospital Supply Co., Ltd.)
• Inventors: Hennige, Carl, Miller, Fred, Kendrick, Paul, Fry, Frank, Sanghvi, Narendra T., DeMarta, Stan, Law, Wing K.
• Primary Examiner(s): JAWORSKI, FRANCIS J
• Application Number:
  US08/446,503
• Time in Patent Office: 1,114 Days
• Field of Search: 128/660.03, 128/662.06, 601/3
• US Class Current: 600/439
• CPC Class Codes: A61B 2017/00274 Prostate operation, e.g. prostatectomy, turp, bhp treatment
• CPC Class Codes: A61B 2018/00547 Prostate
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00
• CPC Class Codes: A61B 8/08 Detecting organic movements or changes, e.g. tumours, cysts, swellings A61B8/02 - A61B8/06 take precedence
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/4281 characterised by sound-transmitting media or devices for coupling the transducer to the tissue
• CPC Class Codes: A61B 8/4405 Device being mounted on a trolley
• CPC Class Codes: A61B 8/445 Details of catheter construction
• CPC Class Codes: A61B 8/4461 Features of the scanning mechanism, e.g. for moving the transducer within the housing of the probe
• CPC Class Codes: A61B 8/461 Displaying means of special interest
• CPC Class Codes: A61B 8/467 characterised by special input means
• CPC Class Codes: A61B 8/483 involving the acquisition of a 3D volume of data
• CPC Class Codes: A61B 8/485 involving measuring strain or elastic properties
• CPC Class Codes: A61N 2007/0065 Concave transducers
• CPC Class Codes: A61N 2007/0078 with multiple treatment transducers
• CPC Class Codes: A61N 7/022 intracavitary

Abstract

A High Intensity Focused Ultrasound system is provided for treatment of focal disease. The preferred embodiment includes an intracavity probe having two active ultrasound radiating surfaces with different focal geometries. Selectively energizing the first surface focuses therapeutic energy a first distance from the housing, energizing the second surface focuses therapeutic energy nearer the housing. Preferably, the probe includes a thin, flexible, inelastic membrane which is rigidized with pressure to allow blunt manipulation of tissue. Methods of use of the probe are also provided, particularly for treatment of diseases of the prostate.

Claims

1. An ultrasound probe comprising a housing having an interior, a first ultrasound radiating surface, a selectively movable support for supporting the first radiating surface, the support having a first end on which the first radiating surface is mounted, and a second end opposite the first end, a seal through which the support extends, the seal dividing the interior into a first chamber at a first end thereof in which the first radiating surface is housed and a second chamber at a second end thereof into which the second end extends, at least a first passageway coupling the first and second chambers, and a piston for closing the second chamber, the piston being movable selectively to alter the volume of the second chamber, and a fluid medium for filling the probe, the fluid medium serving to couple ultrasound between the first radiating surface and a tissue being investigated with the aid of ultrasound transmitted from the first radiating surface, movement of the support to reciprocate the first radiating surface reciprocating the second end of the support in the second chamber to pump the fluid medium back and forth between the first and second chambers, and movement of the piston selectively to reduce and increase the volume of the second chamber increasing and decreasing, respectively, the pressure of the fluid medium in the first and second chambers.

2. The probe of claim 1 wherein the first chamber comprises an acoustically substantially transparent window for coupling ultrasound between the first radiating surface and the tissue being investigated, the acoustically substantially transparent window including an elastically deformable portion separating the first chamber from the exterior of the probe, movement of the piston to decrease the volume of the second chamber elastically deforming the elastically deformable portion.

3. The probe of claim 2 further comprising a second radiating surface mounted on the first end of the support, the support being selectively rotatable to orient the second radiating surface to radiate ultrasound through the acoustically substantially transparent window.

4. The probe of claim 3 and further comprising a second passageway for coupling the first and second chambers, a first one-way valve in the first passageway to prevent fluid flow from the first chamber into the second, and a second one-way valve in the second passageway to prevent fluid flow from the second chamber into the first.

5. The probe of claim 2 and further comprising a second passageway for coupling the first and second chambers, a first one-way valve in the first passageway to prevent fluid flow from the first chamber into the second, and a second one-way valve in the second passageway to prevent fluid flow from the second chamber into the first.

6. The probe of claim 5 wherein the first passageway terminates at a first location within the first chamber and a second location in the second chamber, and the second passageway terminates at a third location in the first chamber and a fourth location in the second chamber, the first location being remote from the third location and the second location being remote from the fourth location.

7. The probe of claim 1 and further comprising a second passageway for coupling the first and second chambers, a first one-way valve in the first passageway to prevent fluid flow from the first chamber into the second, and a second one-way valve in the second passageway to prevent fluid flow from the second chamber into the first.

8. The probe of claim 7 wherein the first passageway terminates at a first location within the first chamber and a second location in the second chamber, and the second passageway terminates at a third location in the first chamber and a fourth location in the second chamber, the first location being remote from the third location and the second location being remote from the fourth location.

9. The probe of claim 4, 5 or 7 wherein the first passageway terminates at a first location within the first chamber and a second location in the second chamber, and the second passageway terminates at a third location in the first chamber and a fourth location in the second chamber, the first location being remote from the third location and the second location being remote from the fourth location.