Luminal stent and device for inserting luminal stent

• US 5,762,625 A
• Filed: 05/03/1994
• Issued: 06/09/1998
• Est. Priority Date: 09/08/1992
• Status: Expired due to Term

• Current Assignee: Kabushikiakisha Igaki Iryo Sekkei
• Original Assignee: Kabushikikaisha Igaki Iryo Sekkei
• Inventors: Igaki, Keiji
• Primary Examiner(s): Buiz, Michael
• Assistant Examiner(s): MULCARE, NANCY C
• Application Number:
  US08/232,181
• Time in Patent Office: 1,498 Days
• Field of Search: 606/192-198, 606/228-231, 604/8, 604/93, 604/154, 604/208, 604/228, 623/1, 623/15, 623/16, 623/12
• US Class Current: 604/8
• CPC Class Codes: A61F 2/885 comprising a coil including a plurality of spiral or helical sections with alternate directions around a central axis
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61F 2250/0098 radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: A61L 31/06 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds A61L31/041 takes precedence
• CPC Class Codes: A61L 31/148 Materials at least partially resorbable by the body
• CPC Class Codes: C08L 67/04 Polyesters derived from hydroxycarboxylic acids, e.g. lactones C08L67/06 takes precedence

Abstract

A luminal stent inserted and fixed in a vessel, such as a blood vessel, so as to maintain the shape of the vessel, and a device for inserting and fixing the luminal stent, are disclosed. The luminal stent is formed of a yarn of bioabsorbable polymer fibers, which yarn is shaped in a non-woven non-knitted state in, for example, a meandering state, around the peripheral surface of an imaginary tubular member. The bioabsorbable polymer includes polylactic acid, polyglycol acid, polyglactin, polydioxanone, polyglyconate, polyglycol acid and a polylactic acid-ε-caprolactone copolymer. The device for inserting and fixing the luminal stent consists in a catheter having a balloon-forming portion in the vicinity of a distal end thereof and the luminal stent fitted on the balloon-forming portion and affixed to the balloon-forming portion by a bio-compatible material, such as an in vivo decomposable polymer, such as polylactic acid, water-soluble protein or fibrin sizing agent.

Claims

1. A luminal stent formed from a single, continuous yarn of continuous bioabsorbable polymer fibers in a non-woven, non-knitted, and meandering state in a shape conforming to a tube.

2. The luminal stent as claimed in claim 1, characterized in that the bioabsorbable polymer is at least one selected from the group consisting of polylactic acid, polyglycol acid, polyglactin (polyglycol acid--polylactic acid copolymer), polydioxanone, polyglyconate (trimethylene carbonate--glycolide copolymer), and a copolymer of ε

-caprolactone with polyglycol acid or polylactic acid.

3. The luminal stent as claimed in claim 1, characterized in that the bioabsorbable polymer fibers are non-circular in cross-section.

4. The luminal stent as claimed in claim 1, characterized in that the bioabsorbable polymer fibers present surface irregularities.

5. The luminal stent as claimed in claim 1, characterized in that at least one of an agent impermeable to X-rays, a carcinostatic agent and an anti-thrombotic agent is mixed into the bioabsorbable polymer fibers.

6. The luminal stent as claimed in claim 1, characterized in that at least one of an agent impermeable to X-rays, a carcinostatic agent, an anti-thrombotic agent and cells of a living body is deposited on the surface of the bioabsorbable polymer fibers.

7. The luminal stent as claimed in claim 1, characterized in that the bioabsorbable polymer fibers are hollow in cross-section.

8. A device for applying a luminal stent comprising:

a catheter having a balloon-forming portion at a distal end thereof; and

a luminal stent formed from a single, continuous yarn of bioabsorbable polymer fibers in a non-woven, non-knitted and meandering state in a shape conforming to peripheral surface of a tube, said luminal stent being fitted over said balloon-forming portion.

9. The device for applying a luminal stent as claimed in claim 8, wherein the luminal stent is coated with a bio-compatible material and thereby affixed to the balloon-forming portion.

10. The device for applying a luminal stent as claimed in claim 9, characterized in that the bio-compatible material is at least one selected from an in vivo decomposable polymer, a water-soluble polymer, water-soluble protein and fibrin sizing agent.

11. The device for applying a luminal stent as claimed in claim 9, characterized in that the bio-compatible material is polylactic acid (PLA).