Immunodiagnostic device

• US 5,763,262 A
• Filed: 04/03/1992
• Issued: 06/09/1998
• Est. Priority Date: 09/18/1986
• Status: Expired due to Term

• Current Assignee: Quidel Corporation
• Original Assignee: Quidel Corporation
• Inventors: Chen, Fon-Chiu Mia, Fan, Eugene, Wong, Siu-Yin
• Primary Examiner(s): Sisson, Bradley L.
• Application Number:
  US07/863,397
• Time in Patent Office: 2,258 Days
• Field of Search: 436/518, 435/287, 435/283.1, 435/287.1, 435/287.2, 435/287.7, 435/288.2, 435/7.1, 422/292, 422/68.1, 422/69, 422/50, 422/55, 422/99, 106/310, 252/400, 252/405
• US Class Current: 435/287.2
• CPC Class Codes: G01N 33/54366 Apparatus specially adapted for solid-phase testing
• CPC Class Codes: G01N 33/76 Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors

Abstract

A device for assaying biological fluids for molecules contained therein comprising a container, material situated in the container for absorbing fluid and in communication with an antibody or antigen impregnated matrix, wherein the matrix is accessible to the exterior of the container through a funnel shaped aperture in the roof of the container. Further features include a chemical drying agent associated with the container for absorbing moisture, thereby preventing inactivation of the assay reagents, and a filter situated above the antibody or antigen impregnated matrix, and in communication with the matrix through the aperture in the roof of the container. The filter removes interfering substances present in the biological fluids and provides protein blocking agents to the matrix material for decreasing the background of the assay.

Claims

1. In an immunoassay device having a housing with at least one opening therethrough for introduction of a liquid sample into the housing, a web of porous material in said housing adapted to be contacted by said liquid sample, and at least one immunological reagent in dried form on said web, the improvement comprising:

a desiccant material in said housing, wherein said desiccant is capable of retarding deterioration of said reagent.