Tracheal tube and ventilator system permitting endogenously-produced NO to be combined with respiratory gas

• US 5,765,558 A
• Filed: 10/07/1996
• Issued: 06/16/1998
• Est. Priority Date: 10/13/1995
• Status: Expired due to Fees

• Current Assignee: Maquet Critical Care AB (Getinge AB)
• Original Assignee: Siemens Elema AB
• Inventors: Psaros, Georgios, Hognelid, Kurt
• Primary Examiner(s): Lewis, Aaron J.
• Assistant Examiner(s): SRIVASTAVA, VIRENDRA KUMAR
• Application Number:
  US08/726,669
• Time in Patent Office: 617 Days
• Field of Search: 128/207.14, 128/207.16, 128/207.18, 128/911, 128/200.26, 128/203.22, 128/204.18, 128/204.21, 128/204.23, 128/203.12, 128/207.29 , 128/206.11, 128/201.26, 128/200.14
• US Class Current: 128/207.14
• CPC Class Codes: A61M 16/04 Tracheal tubes catheters in general A61M25/00
• CPC Class Codes: A61M 16/042 with separate conduits for in-and expiration gas, e.g. for limited dead volume
• CPC Class Codes: A61M 16/0461 Nasoendotracheal tubes
• CPC Class Codes: A61M 16/0833 T- or Y-type connectors, e.g. Y-piece
• CPC Class Codes: A61M 2202/0275 Nitric oxide [NO]
• CPC Class Codes: Y10S 128/911 Unilimb inhalation-exhalation breathing tubes

Abstract

A ventilator system and a tracheal tube, inserted into a patient'"'"'s trachea to carry gas to and from the lungs, permit a gas mixture containing endogenous NO, which is present in the upper respiratory tract, to be supplied to the lungs. The tracheal tube has a input port which forms a connection between the interior of the tracheal tube and the upper respiratory tract. The input port draws or forces an amount of the gas containing endogenous NO into the tracheal tube and this gas accompanies the respiratory gas into the lungs during inspiration.

Claims

1. A tracheal tube having a proximal end and a distal end adapted for insertion into a patient'"'"'s trachea with said distal end conducting, via a flow path between the proximal end and the distal end in the tracheal tube, a respiratory gas to a patient'"'"'s lungs, said tracheal tube having an input port, said input port comprising means for connecting an exterior of said tracheal tube to said flow path through said input port for causing gas, containing produced endogenously NO by a patient, to flow from a patient'"'"'s upper respiratory tract into said flow path during inspiration by a patient.

2. A tracheal tube as claimed in claim 1, wherein said input port is disposed a distance from said distal end of said tracheal tube for positioning said input port below the patient'"'"'s upper respiratory tract when said tracheal tube is inserted into a patient'"'"'s trachea.

3. A tracheal tube as claimed in claim 1 having a tube wall, said input port comprising an unobstructed tube disposed in said tube wall of said tracheal tube and having a first tube opening and a second tube opening, said first tube opening being disposed outside of said tracheal tube and said second tube opening being disposed in said flow path, facing said distal end of said tracheal tube.

4. A tracheal tube as claimed in claim 3 wherein said unobstructed tube has a predetermined length inside said tracheal tube with at least a portion of said predetermined length extending parallel to said flow path.

5. A tracheal tube as claimed in claim 3 wherein said first tube opening is larger than said second tube opening.

6. A tracheal tube as claimed in claim 5 wherein said unobstructed tube is funnel-shaped.

7. A tracheal tube as claimed in claim 1 having a tube wall with an interior tube wall surface, and wherein said input port comprises an inner wall disposed inside said tracheal tube spaced from said interior tube wall surface and defining a spacing between said inner wall and said interior tube wall surface, said spacing having an upper end communicating through an opening in said tube wall with an exterior of said tracheal tube and having a lower end communicating with the interior of said tracheal tube.

8. A tracheal tube as claimed in claim 1 wherein said input port comprises a nasal tube having a first end adapted for insertion into a patient'"'"'s nostril and having a second end, an ejector valve means, connecting said second end of said nasal tube to said flow path, for drawing gas via said nasal tube into said flow path when said respiratory gas is conveyed through said tracheal tube.

9. A tracheal tube as claimed in claim 1 wherein said input port comprises flow control means allowing gas to flow from the exterior of said tracheal tube into said flow path and for preventing gas from flowing from said flow path to the exterior of said tracheal tube via said input port.

10. A tracheal tube as claimed in claim 9 wherein said flow control means comprise a one-way valve.

11. A tracheal tube as claimed in claim 1 having tube wall and wherein said input port comprises a NO-permeable membrane disposed in said tube wall between an exterior of said tracheal tube and said flow path and permitting diffusion of NO from the exterior of said tracheal tube into said flow path through said membrane.

12. A tracheal tube as claimed in claim 1 wherein said input port comprises a micropump which pumps gas from an exterior of said tracheal tube into said flow path.

13. A tracheal tube as claimed in claim 12 for use with a ventilation system having a control unit which regulates inspiratory and expiratory phases of said patient, and wherein said micropump is operated by said control unit for activating said micropump in synchronism with each inspiratory phase.

14. A tracheal tube as claimed in claim 13 wherein said control unit activates said micropump for a predetermined period of time at a beginning of each inspiratory phase.

15. A tracheal tube as claimed in claim 11 further comprising means for operating said micropump for pumping a predetermined volume of gas from said exterior of said tracheal tube into said flow path.

16. A ventilation system comprising:

a tracheal tube having a proximal end and a distal end with a flow path therebetween, said distal end being adapted for insertion into a patient'"'"'s trachea;

respiratory assist means, connected to said proximal end of said tracheal tube, for supplying respiratory gas to a patient'"'"'s lungs;

a tubular arrangement having a first end adapted for insertion into a patient'"'"'s nostril for conveying a gas toward said first end during inspiration phases of a patient; and

said tracheal tube having at least one gas communication path disposed at a predetermined distance from said distal end of said tracheal tube which connects an exterior of said tracheal tube with a flow path within said tracheal tube, said gas communication path causing gas, containing NO endogenously produced by a patient, to flow from a patient'"'"'s upper respiratory tract into said flow path during inspiration by a patient.

17. A ventilation system as claimed in claim 16 wherein said tubular arrangement is connected to said respiratory-assist means via an opening facing said ventilator.

18. A ventilation system as claimed in claim 16 wherein said tubular arrangement has a second end connected to said proximal end of said tracheal tube.

19. A ventilation system as claimed in claim 16 wherein said tubular arrangement includes a one-way valve which prevents gas from flowing from said first end through said tubular arrangement to said respiratory-assist means.

20. A ventilation system as claimed in claim 19 further comprising at least one micro-valve in said tracheal tube for opening said gas communication path during said inspiration phases.

21. A ventilation system comprising:

a tracheal tube having a proximal end and a distal end, said distal end being adapted for insertion into a patient'"'"'s trachea;

respiratory assist means, connected to said proximal end of said tracheal tube, for supplying respiratory gas to a patient'"'"'s lungs through said tracheal tube along a respiratory gas path;

a tubular arrangement having a first end adapted for insertion into a patient'"'"'s nostril and a second end in communication with said respiratory gas path said gas communication path causing gas, containing NO endogenously produced by a patient, to flow from a patient'"'"'s upper respiratory tract into said flow path during inspiration by a patient; and

means for generating a gas flow from said first end of said tubular arrangement to said respiratory gas path during inspiration phases of a patient.

22. A ventilation system as claimed in claim 21 wherein said means for generating a gas flow comprises an ejector device disposed at a second end of said tubular arrangement.

23. A ventilation system as claimed in claim 21 wherein said means for generating a gas flow comprises a micropump disposed for pumping gas through said tubular arrangement.