Non-invasive blood analyzer and method using the same

• US 5,769,076 A
• Filed: 05/02/1996
• Issued: 06/23/1998
• Est. Priority Date: 05/02/1995
• Status: Expired due to Fees

• Current Assignee: Ken Ishihara
• Original Assignee: Toa Medical Electronics Co., Ltd.
• Inventors: Maekawa, Yasunori, Kochi, Yasuhiro, Ishihara, Ken, Asano, Kaoru
• Primary Examiner(s): Bahr, Jennifer
• Assistant Examiner(s): WINAKUR, ERIC FRANK
• Application Number:
  US08/641,828
• Time in Patent Office: 782 Days
• Field of Search: 128/633, 128/637, 128/664, 128/665, 356/39
• US Class Current: 600/322
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters

Abstract

A non-invasive blood analyzer contains a light applicator for illuminating a detection region under the skin of a living body including a blood vessel; a camera for capturing an image of the illuminated detection region; an analyzer for processing the captured image and analyzing at least a component of blood in the blood vessel; a transparent plate; and a support for supporting the transparent plate and contacting the transparent plate closely with the skin over the detection region. The light applicator and the camera are constructed to illuminate the detection region and capture the image of the detection region through the transparent plate. Further, a drive controller is included for driving the support to move the transparent plate contacted closely with the skin in order to adjust the detection region to thereby compensate for any change in position of the blood vessel.

Claims

1. A non-invasive blood analyzer comprising:

light application device for illuminating a detection region including a blood vessel having blood flowing therethrough, the detection region being under skin of a part of a living body;

image capturing device for capturing an image of the illuminated detection region;

analysis device for processing the captured image and analyzing at least a component of the blood in the blood vessel in the detection region;

a transparent plate contacting the skin, the light application device illuminating the detection region through the transparent plate and the image capturing device capturing the image of the detection region through the transparent plate;

support device for supporting the transparent plate; and

drive control device for driving the support device to move the transparent plate in order to adjust the detection region.

2. The non-invasive blood analyzer of claim 1, wherein the analysis means is further for determining a diameter of the blood vessel and for comparing the diameter with a predetermined value, and wherein the drive control device controls the support device to move the transparent plate by a predetermined distance when the diameter is smaller than the predetermined value.

3. The non-invasive blood analyzer of claim 1, wherein the analysis means is further for processing the image and for determining a difference in position of repeatedly captured images with respect to the blood vessel, and wherein the drive control device controls the support device to move the transparent plate so as to minimize the determined difference.

4. The non-invasive blood analyzer of claim 3, further comprising a memory for storing at least one captured image.

5. The non-invasive blood analyzer of claim 4, wherein the memory stores an initially captured image as a reference image and the analysis device compares a position of a blood vessel in the reference image with a position of the blood vessel of a next-captured image, captured after the support device has moved the transparent plate by a predetermined distance.

6. The non-invasive blood analyzer of claim 5, wherein the image capturing device captures an image of a blood vessel after the support device moves the transparent plate so as to minimize the determined distance, the analysis device analyzing a component of the blood in the blood vessel in the last captured image.

7. The non-invasive blood analyzer of claim 1, wherein the support means includes a support plate, having an opening therein, for receiving the transparent plate.

8. The non-invasive blood analyzer of claim 1, wherein the support means includes a support plate, having and opening therein, for receiving the transparent plate;

a sliding board to which the support plate is exchangeably attached; and

a support member for slidably supporting the sliding board.

9. The non-invasive blood analyzer of claim 1, wherein the support means includes a support member for slidably supporting the transparent plate.

10. The non-invasive blood analyzer of claim 9, wherein the drive control means includes bias means for biasing the transparent plate in a sliding direction and pressing means for moving the transparent plate.

11. The non-invasive blood analyzer of claim 10, wherein the bias means includes a spring and the pressing device includes a rod and a motor for moving the rod.

12. The non-invasive blood analyzer of claim 1, wherein the transparent plate is made of either glass or a plastic sheet.

13. The non-invasive blood analyzer of claim 1, wherein the support device includes a support member for slidably supporting the transparent plate and fixing device for fixing the support member on the living body.

14. The non-invasive blood analyzer of claim 1, further comprising a memory for storing the captured image.

15. A method of non-invasively analyzing blood, comprising the steps of:

illuminating a detection region through a movable transparent plate, the detection region being under skin of a part of a living body and including a blood vessel having blood flowing therethrough;

capturing an image of the detection region illuminated through the transparent plate;

analyzing a component of the blood in the blood vessel in the detection region; and

driving a support, supporting the transparent plate, with a driving device to move the transparent plate in order to adjust the detection region.

16. The method of non-invasively analyzing blood of claim 15, further comprising the steps of:

successively capturing images of the detection region under the skin shifted by the driving device;

comparing a diameter of each captured blood vessel image with a predetermined value; and

analyzing a component of the blood contained in the blood vessel when the captured blood vessel image is larger than the predetermined value in diameter.

17. The method of non-invasively analyzing blood of claim 15, further comprising the steps of:

capturing at least two images of the blood vessel;

determining a difference in position between the at least two captured images with respect to the blood vessel;

moving the transparent plate by a distance such that the determined difference is minimized; and

capturing a next image of the blood vessel after the transparent plate has been moved.

18. A non-invasive blood analyzer comprising:

a light source for illuminating a detection region through a movable transparent device, the detection region being under skin of a part of a living body and including a blood vessel;

a light capturing device for capturing an image of the detection region illuminated through the transparent device;

an analyzer for analyzing the captured image and determining whether or not a captured blood vessel image is larger in diameter than a predetermined value;

memory for storing the captured image if the diameter of the image of the captured blood vessel is determined to be larger than the predetermined value; and

a controller for controlling the transparent device to move by a predetermined distance when the diameter of the image of the captured blood vessel is not determined to be larger than the predetermined value.

19. The non-invasive blood analyzer of claim 18, wherein the light capturing device captures a next image of the detection region illuminated through the transparent device subsequent to the controller controlling the transparent device to move by a predetermined distance,

the analyzer determines a difference between the stored captured image and the captured image with respect to the blood vessel,

the controller controls the transparent device to move so as to minimize the difference, and

the light capturing device thereafter captures a final image of the blood vessel.