Gas filled liposomes and stabilized gas bubbles and their use as ultrasonic contrast agents
First Claim
Patent Images
1. A gas filled liposome prepared by a vacuum drying gas instillation method.
15 Assignments
0 Petitions
Accused Products
Abstract
Contrast agents for ultrasonic imaging comprising gas filled liposomes prepared using vacuum drying gas instillation methods, and gas filled liposomes substantially devoid of liquid in the interior thereof, are described. Methods of and apparatus for preparing such liposomes and methods for employing such liposomes in ultrasonic imaging applications are also disclosed. Also described are diagnostic kits for ultrasonic imaging which include the subject contrast agents.
-
Citations
56 Claims
- 1. A gas filled liposome prepared by a vacuum drying gas instillation method.
- 21. A gas filled liposome substantially devoid of liquid in the interior thereof.
- 41. A contrast agent adapted to be inject ed in to the body of a patient and comprising stabilized gas bubbles which comprises gas encapsulated by one or more lipid materials, said stabilized gas bubbles being substantially devoid of liquid in the interior thereof.
Specification