Anti-bacterial, UV absorbable, tinted, metal-chelating polymers

• US 5,770,637 A
• Filed: 05/01/1996
• Issued: 06/23/1998
• Est. Priority Date: 05/01/1996
• Status: Expired due to Term

• Current Assignee: Johnson & Johnson Vision Products, Inc.
• Original Assignee: Johnson & Johnson Vision Products, Inc.
• Inventors: Vanderlaan, Douglas G., Orr, Susan B.
• Primary Examiner(s): MERRIAM, ANDREW EDWIN
• Application Number:
  US08/641,409
• Time in Patent Office: 783 Days
• Field of Search: 523/106, 524/555, 524/916, 526/307, 526/306, 351/160 H
• US Class Current: 523/106
• CPC Class Codes: G02B 1/043 Contact lenses
• CPC Class Codes: G02B 5/223 containing organic substances, e.g. dyes, inks or pigments
• CPC Class Codes: Y10S 524/916 Hydrogel compositions

Abstract

A soft contact lens which comprises a water-swollen gel of a polymer prepared by polymerizing one or more hydrophilic monomers such as 2-hydroxyethyl methacrylate, one or more cross-linking monomers, a monomer that contains metal-chelating functionality such as an aminopolycarboxylic acid that contains a polymerizable olefinic group, and an effective amount of iron to absorb UV light and/or an effective amount of copper to cause the lens to be tinted.

Claims

1. A soft contact lens which comprises a water-swollen gel of a polymer prepared by polymerizing one or more hydrophilic monomers, one or more cross-linking monomers, and a monomer which contributes or which can, after completion of lens polymerization, be developed to contribute, metal-chelating functionality, wherein the monomer that contributes metal-chelating functionality is selected from the group consisting of methacrylic acid amides containing an alkylamino-N,N-diacetic acid group, and acrylic acid amides containing an alkylamino-N,N-diacetic acid group.

8. The soft contact lens of claim 1 to which copper has been added in an amount sufficient to add enough color to the lens to render it visible in normal contact lens storage or cleaning fluids without resulting in an unacceptable loss of lens clarity.

11. The contact lens according to claim 1, wherein said monomer that contributes metal-chelating functionality is selected from the group consisting of methacrylic acid amides containing an alkylamino-N,N-diacetic acid group.

12. The contact lens according to claim 1, wherein said monomer that contributes metal-chelating functionality is selected from the group consisting of acrylic acid amides containing an alkylamino-N,N-diacetic acid group.

15. The soft contact lens of claim 1 to which iron has been added.

2. A soft contact lens which comprises a water-swollen gel of a polymer prepared by polymerizing one or more hydrophilic monomers, one or more cross-linking monomers, and a monomer which contributes or which can, after completion of lens polymerization, be developed to contribute, metal-chelating functionality, wherein the monomer that contributes metal-chelating functionality is selected from the group consisting of methacrylic acid amides containing an allylamino-N,N-diester group, and acrylic acid amides containing an alkylamino-N,N-diester group.

5. The soft contact lens of claim 2 to which iron has been added.

13. The contact lens according to claim 2, wherein said monomer that contributes metal-chelating functionality is selected from the group consisting of methacrylic acid amides containing an alkylamino-N,N-diester group.

14. The contact lens according to claim 2, wherein said monomer that contributes metal-chelating functionality is selected from the group consisting of acrylic acid amides containing an alkylamino-N,N-diester group.

16. The soft contact lens of claim 2 to which copper has been added in an amount sufficient to add enough color to the lens to render it visible in normal contact lens storage or cleaning fluids without resulting in an unacceptable loss of lens clarity.

3. A soft contact lens which comprises a water-swollen gel of a polymer prepared by polymerizing one or more hydrophilic monomers, one or more cross-linking monomers, and a monomer which contributes or which can, after completion of lens polymerization, be developed to contribute, metal-chelating functionality, wherein the monomer that contributes metal-chelating functionality is an ester of aminopropylmethacrylamide-N,N-diacetic acid.

6. The soft contact lens of claim 3, to which iron has been added.

9. The soft contact lens of claim 3, to which copper has been added in an amount sufficient to add enough color to the lens to render it visible in normal contact lens storage or cleaning fluids without resulting in an unacceptable loss of lens clarity.

4. A soft contact lens which comprises a water-swollen gel of a polymer prepared by polymerizing one or more hydrophilic monomers, one or more cross-linking monomers, and a monomer which contributes or which can, after completion of lens polymerization, be developed to contribute, metal-chelating functionality, wherein the monomer that contributes metal-chelating functionality is an aminopropylmethacrylamide-N,N-diacetic acid diethyl ester.

7. The soft contact lens of claim 4, to which iron has been added.

10. The soft contact lens of claim 4, to which copper has been added in an amount sufficient to add enough color to the lens to render it visible in normal contact lens storage or cleaning fluids without resulting in an unacceptable loss of lens clarity.