Container with multi-phase composition for use in diagnostic and therapeutic applications
First Claim
Patent Images
1. A container which contains a composition comprising an aqueous phase and a gaseous phase substantially separate from said aqueous phase, wherein said aqueous phase comprises a lipid suspended therein and said gaseous phase comprises sulfur hexafluoride gas, and wherein said composition is capable of forming lipid spheres encapsulating the gas upon agitation of the container.
12 Assignments
0 Petitions
Accused Products
Abstract
A container comprising an aqueous lipid suspension and a gaseous phase substantially separate from the aqueous stabilizing phase, useful in diagnostic imaging such as ultrasound and magnetic resonance imaging and in therapeutic applications, is disclosed.
233 Citations
51 Claims
- 1. A container which contains a composition comprising an aqueous phase and a gaseous phase substantially separate from said aqueous phase, wherein said aqueous phase comprises a lipid suspended therein and said gaseous phase comprises sulfur hexafluoride gas, and wherein said composition is capable of forming lipid spheres encapsulating the gas upon agitation of the container.
- 25. A container which contains a composition for use in diagnostic imaging, wherein the composition comprises an aqueous phase and a gaseous phase which comprises sulfur hexafluoride, wherein said aqueous phase includes a lipid suspended therein and the composition is capable of forming lipid spheres encapsulating the gas upon agitation of the container.
- 47. A container which contains a composition for use in diagnostic imaging, wherein the composition comprises an aqueous phase and a substantially separate gaseous phase, said aqueous phase comprising lipid suspended therein and said gaseous phase comprising a substantially insoluble gas in combination with a soluble gas, wherein the composition is capable of forming lipid spheres encapsulating the gas upon agitation of the container.
Specification