Method and device for treating intracranial vascular aneurysms

• US 5,776,097 A
• Filed: 12/19/1996
• Issued: 07/07/1998
• Est. Priority Date: 12/19/1996
• Status: Expired due to Term

• Current Assignee: University of California Los Angeles (University of California)
• Original Assignee: University of California Los Angeles (University of California)
• Inventors: Massoud, Tarik F.
• Primary Examiner(s): YASKO JR, JOHN D
• Application Number:
  US08/770,694
• Time in Patent Office: 565 Days
• Field of Search: 604/49, 604/51-53, 604/96, 604/101-104, 606/191, 606/192
• US Class Current: 604/500
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12045 double occlusion, e.g. during anastomosis
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 17/12186 liquid materials adapted to be injected
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters

Abstract

A device and method for the therapeutic management of intracranial vascular aneurysms are provided involving the use of intravascular balloon catheters that can directly image the aneurysm and that can occlude the entire lumen of the aneurysm sac using liquid sealing agents. The intracranial catheters, according to the present invention, have various configurations designed to treat aneurysms regardless of the aneurysm'"'"'s neck size and at different locations within the intracranial vascular system.

Claims

1. A device for treating an intracranial vascular aneurysm located on an intracranial blood vessel, the blood vessel having a lumen and the aneurysm having a lumen, the device comprising:

a catheter including a central lumen therethrough, a first inflation conduit having a distal end, and a first inflation balloon in communication with the distal end of the inflation conduit;

the catheter further including means for visualizing the blood vessel lumen adjacent the aneurysm lumen, the means for visualizing in combination with the central lumen; and

the catheter further including means for delivering a liquid sealing agent to the lumen of the aneurysm, the means for delivering in combination with the central lumen.

2. The device of claim 1, wherein the first inflation balloon is configured to substantially surrounds the central lumen when the first inflation balloon is inflated.

3. The device of claim 1, wherein the means for visualizing comprises a microangioscope.

4. The device of claim 1, wherein the means for delivering comprises a microcatheter.

5. The device of claim 1, further including a second inflation conduit having a distal end, and a second inflation balloon in communication with the distal end of the second inflation conduit.

6. The device of claim 5, further including a third inflation conduit having a distal end, and a third inflation balloon in communication with the distal end of the third inflation conduit.

7. A device for treating an intracranial vascular aneurysm located on an intracranial blood vessel, the blood vessel having a lumen and the aneurysm having a lumen, the device comprising:

a catheter including a central lumen therethrough, an inflation conduit having a distal end, and an inflation balloon in communication with the distal end of the inflation conduit;

the catheter further including means for visualizing the blood vessel lumen adjacent the aneurysm lumen, the means for visualizing in combination with the central lumen;

the catheter further including means for delivering a liquid sealing agent to the aneurysm lumen, the means for delivering in combination with the central lumen;

the catheter further including in combination with the central lumen, a second inflation conduit having a distal end, and a second inflation balloon in communication with the distal end of the second inflation conduit; and

the catheter further including in combination with the central lumen, a third inflation conduit having a distal end, and a third inflation balloon in communication with the distal end of the third inflation conduit.

8. A method of treating an aneurysm of an intracranial blood vessel, the aneurysm having a sac, the method comprising the steps of:

(a) inserting a catheter having a proximal end and a distal end into the blood vessel containing the aneurysm, wherein the catheter includes a central lumen therethrough, and wherein the catheter further includes an inflation conduit connected to an inflation balloon;

(b) advancing the catheter until the distal end is proximate the aneurysm;

(c) inflating the balloon such that the balloon and catheter substantially occlude the blood vessel adjacent the aneurysm;

(d) delivering a sealing agent through the central lumen into the aneurysm sufficient to substantially fill the aneurysm; and

(e) removing the catheter from the blood vessel.

9. The method of claim 8, further comprising the step, after the inflating step (c), of delivering an irrigation substance into the blood vessel adjacent the aneurysm through the central lumen to substantially remove blood from aneurysm sac and blood vessel adjacent the aneurysm, thereby creating a substantially clear view of the aneurysm sac.

10. The method of claim 8, further comprising the step, before the delivering step (d), of visualizing the aneurysm sac using an intravascular microangioscope.

11. The method of claim 8, further comprising the step, before the delivering step (d), of placing the aneurysm sac into a gravity dependent position.

12. The method of claim 8, wherein the catheter comprises an additional inflation balloon and wherein the method further comprises the step, before the delivering step (d), of inflating the additional balloon to block backflow from the blood vessel or from collateral blood vessels.