Injector module for a syringe and pre-filled syringe provided therewith

• US 5,779,683 A
• Filed: 11/29/1995
• Issued: 07/14/1998
• Est. Priority Date: 02/14/1994
• Status: Expired due to Term

• Current Assignee: Sanofi-Aventis (Sanofi )
• Original Assignee: Medicorp Holding S.A.
• Inventors: Meyer, Gabriel
• Primary Examiner(s): Buiz, Michael
• Assistant Examiner(s): NGUYEN, ANH TUAN TUONG
• Application Number:
  US08/532,704
• Time in Patent Office: 958 Days
• Field of Search: 604/198, 604/86-89, 604/200, 604/201, 604/205, 604/195-197, 604/187, 604/110, 604/232, 604/192
• US Class Current: 604/198
• CPC Class Codes: A61M 5/2429 by telescoping of ampoules or carpules with the syringe body
• CPC Class Codes: A61M 5/2448 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/283 by telescoping of ampoules or carpules with the syringe body
• CPC Class Codes: A61M 5/3243 being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel devices for protecting guide needles in combination with catheters A61M25/0612

Abstract

An injector module (40) and a one- or two-component syringe comprising the same, the module including a cylindrical barrel (41), a needle (43) extending from the end thereof, and a protective sleeve (42) for said needle. The sleeve consists of a single rigid member axially slidable over the cylindrical barrel (41). The cylindrical barrel is provided with a skirt (46) with at least one flexible tab (47) engageable with an inner ring-shaped rib (50) of the rigid cylindrical sleeve to prevent the return of the sleeve once it has been moved forward. For this purpose, the flexible tabs (47) comprise a slanted end (47a) and a rounded edge (47b) which engage said inner rib.

Claims

1. An injector module having a syringe subassembly, said module comprising:

a cylindrical barrel having a distal and proximate extremity;

a needle extending from said proximate extremity and attached to said barrel by a needle-holder tip;

a sleeve being movable between a retracted position, exposing said needle, and an advanced position, covering said needle,

wherein said sleeve comprises a single rigid piece telescopically interlocked with and axially slidable on said barrel;

an annular skirt, attached to said proximate extremity, surrounding said needle-holder tip (45);

at least two diametrically opposed flexible tabs on said skirt that cooperate with an interior annular rib (50) on said rigid piece to form an anti-return device when said sleeve is in the advanced position; and

at least one stop means also cooperating with said annular rib (50) on said sleeve thereby to define a path of said sleeve when said sleeve is in the advanced position, said stop means comprising an annular protruding rib extending across two diametrically opposed circular portions respectively located between said flexible tabs.

2. An injector module as defined in claim 1 wherein said annular protruding rib is located at an end of said annular skirt (46).

3. An injector module as defined in claim 1 wherein said stop means (48) comprises an acutely angled side defining said protruding annular rib (49) in relation to said skirt (46).

4. An injector module as defined in claim 1 wherein said interior annular rib (50) on said sleeve (42) is defined by sides (55, 56) forming angles (53, 54) in relation to an interior wall of said sleeve (42).

5. An injector module as defined in claim 4 wherein said angles (53, 54) forming the sides with said interior wall are lesser than or equal to 90°

.

6. An injector module as defined in claim 4 wherein said angles (54, 53) are respectively complementary to an angle of an extremity (47a, 67a) of each of said at least two flexible tabs and to an acute angle which defines said annular protruding rib (49) on said sleeve in relation to said skirt.

7. An injector module as defined in claim 1 wherein each of said flexible tabs (47, 67) comprise, opposite a slanted extremity thereof (47a, 67a), a curved edge (47b, 67b) cooperating with a side (55) of the interior rib (50) when the sleeve (42, 62) is placed in the advanced position.

8. An injector module as defined in claim 1 wherein said sleeve is generally cylindrical in shape, said sleeve further comprising, at a position substantially level with said interior rib, an interior diameter (52) that is generally equal to an exterior diameter of the cylindrical barrel (41).

9. An injector module as defined in claim 8 wherein said sleeve (42) has rigid lateral walls which are completely closed.

10. An injector module as defined in claim 8 wherein said sleeve (62) has rigid lateral walls with several openings (70) therein arranged about a peripheral circle on said sleeve in order for said openings to cooperate with prongs on a suitable gripping device.

11. An injector module as defined in claim 8, wherein said sleeve (42) has handles extending laterally and symmetrically along at least one portion of a perimeter of said distal extremity.

12. An injector module as defined in claim 11 wherein said handles consist of two lateral flanges.

13. An injector module as defined in claim 11 wherein said handles comprise an annular rim (51).

14. A prefilled syringe having at least one compartment for holding a medicinal substance that is to be reconstituted by mixing with another component, said syringe comprising

(i) an injector module, which further comprises:

a cylindrical barrel having a distal and proximate extremity;

a needle extending from said proximate extremity and attached to said barrel by a needle-holder tip;

a sleeve being movable between a retracted position exposing said needle and an advanced position covering said needle,

wherein said sleeve comprises a single rigid piece telescopically interlocked with and axially slidable on said barrel;

an annular skirt, attached to said proximate extremity, surrounding said needle-holder tip;

at least two diametrically opposed flexible tabs on said skirt that cooperate with an interior annular rib on said rigid piece to form an anti-return device when said sleeve is in the advanced position; and

at least one stop means also cooperating with said annular rib on said sleeve thereby to define a path of said sleeve when said sleeve is in the advanced position, said stop means comprising an annular protruding rib extending across two diametrically opposed circular portions respectively located between said flexible tabs;

and (ii) a propulsion receptacle module, which further comprises;

at least one receptacle for defining said compartment, said receptacle being slidable within said barrel to act as a piston shaft; and

at least one stopper for containing said medicinal substance within said receptacle, said stopper being slidable within said receptacle to act as a piston.

15. A syringe as defined in claim 14 wherein said barrel comprises a piston (81) and a piston shaft (82) engaged therein.

16. A syringe as defined in claim 14 wherein said receptacle comprises a reservoir (101), closed at one end and blocked at the other end by a piston-valve-stopper (102), connected to a transfer device (103) having a tubular shaft for communication between the reservoir and said needle (105) of the injector module.

17. A syringe as defined in claim 14 wherein said needle of the injector module is a double needle, with one point located inside said cylindrical barrel, and said receptacle comprises a container (113), closed at one end and blocked at the other end by a stopper (114), which can be perforated by said one point.

18. A syringe as defined in claim 14 wherein said needle (125) of the injector module is a double needle having one point thereof located inside the cylindrical barrel and said receptacle (121) is closed at one end by a stopper (122), said stopper designed to receive a piston shaft (123), and closed at the other end by a membrane and a crimped capsule which are capable of being perforated by said one point.