Element and system for collecting, transporting and storing sample material to be analyzed

• US 5,783,759 A
• Filed: 06/24/1996
• Issued: 07/21/1998
• Est. Priority Date: 06/24/1995
• Status: Expired due to Fees

• Current Assignee: Boehringer Mannheim GmbH (Roche Holding AG)
• Original Assignee: Boehringer Mannheim GmbH (Roche Holding AG)
• Inventors: Werner, Wolfgang, Lerch, Rolf, Wielinger, Hans
• Primary Examiner(s): NOLAND, THOMAS
• Application Number:
  US08/668,916
• Time in Patent Office: 757 Days
• Field of Search: 73/864.71, 73/864.72, 73/84.56
• US Class Current: 73/864.72
• CPC Class Codes: B01L 2200/185 Long distance transport, e.g. mailing
• CPC Class Codes: B01L 2300/0825 Test strips
• CPC Class Codes: B01L 2400/0406 capillary forces
• CPC Class Codes: B01L 3/5023 with a sample being transported to, and subsequently stored in an absorbent for analysis
• CPC Class Codes: B01L 99/00 Subject matter not provided for in other groups of this subclass
• CPC Class Codes: G01N 2001/149 Capillaries; Sponges
• CPC Class Codes: G01N 2001/2826 Collecting by adsorption or absorption
• CPC Class Codes: G01N 33/525 Multi-layer analytical elements

Abstract

Disclosed is an element for collecting, transporting and storing sample material to be analyzed containing absorptive matrix material. The element contains a first and a second layer of absorptive matrix material which are arranged side by side, next to, and touching one another on an inert support material in a contact enabling liquid transfer in such a manner that liquid can pass from the first into the second layer when the first layer is filled with liquid. The first layer can be completely separated from the second layer after applying and drying the sample material. Also disclosed is a system containing such an element and a closable envelope in which the element can be transported. In addition, the invention concerns a method for analyzing a liquid sample material in which the liquid sample material is applied to an element according to the invention, the first layer is separated from the second layer of absorptive matrix material for analysis and is subsequently eluted.

Claims

1. An element for collecting, transporting and storing a sample material to be analyzed, the element comprising:

an inert support material;

a first and second layer of absorptive matrix material arranged side by side next to and touching one another on the inert support material in a contact enabling transfer of liquid from the first layer into the second layer when the first layer is filled with liquid, the first layer being completely separable from the second layer after having applied the sample material.

2. The element of claim 1 wherein the support material has an end with a recess and the layers of absorptive matrix material are arranged at the end of the support material in such a manner that the first layer is located at the end of the support material so that the first layer can be gripped and removed from the element.

3. The element of claim 1 wherein the support material contains a predetermined breaking location.

4. The element of claim 3 wherein the first and second layers of absorptive matrix material are fixed on the inert support material in such a way that two opposite ends of the support material are free and can be gripped.

5. The element of claim 3 wherein the element can be broken at the predetermined breaking location by bending the element in such a manner that two parts are obtained of which the first carries the first and the other the second matrix material layer.

6. The element of claim 1 wherein the absorptivity of the first layer of matrix material is the same as, or greater than, that of the second layer of matrix material.

7. The element of claim 6 wherein the first layer of matrix material comprises cellulose fibers.

8. The element of claim 1 wherein the first layer comprises polyester fibers, viscose and polyvinylalcohol.

9. A system comprising:

an element of claim 1 and a closable envelope in which the element can be transported.

10. The system of claim 9 wherein the envelope has a front part, two side parts, a back flap and a closure flap, said element being securely but detachably, fixed to the back flap of the envelope.

11. The system of claim 10 further comprising means for securing the sample to the back flap of the envelope.

12. The system of claim 11 wherein the means for securing comprise a clamping device or an adhesive tape.