Inhalation device

• US 5,787,881 A
• Filed: 02/03/1997
• Issued: 08/04/1998
• Est. Priority Date: 02/27/1993
• Status: Expired due to Fees

• Current Assignee: Fisons PLC (Sanofi )
• Original Assignee: Fisons PLC (Sanofi )
• Inventors: Chawla, Brindra Paul Singh
• Primary Examiner(s): Lewis, Aaron J.
• Application Number:
  US08/789,073
• Time in Patent Office: 547 Days
• Field of Search: 128/203.15, 128/203.21, 604/58
• US Class Current: 128/203.15
• CPC Class Codes: A61M 15/0028 using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
• CPC Class Codes: A61M 15/0031 by bursting or breaking the package, i.e. without cutting or piercing
• CPC Class Codes: A61M 2202/064 Powder
• CPC Class Codes: A61M 2206/16 Rotating swirling helical flow, e.g. by tangential inflows

Abstract

A device for the administration of powdered inhalation medicament contained initially in a capsule having at least one aperture formed therein, comprising a swirl chamber (1) adapted to receive the medicament capsule; a mouthpiece (2) communicating with the swirl chamber (1) and separated therefrom by a grid (4); at least one air inlet (5) in tangential communication with the swirl chamber (1) whereby air can be drawn through the device via the mouthpiece (2) to cause a swirling air flow through the swirl chamber (1); and a cover member (7), having a continuous substantially planar inner surface, provided on the base of the swirl chamber (1) remote from the mouthpiece (2); said cover (7) being moveable between a first position in which the capsule can be inserted into the swirl chamber (1) and a second position in which the capsule is retained in the swirl chamber (1) and rotates upon air being drawn through the device, thereby dispensing the medicament contained therein.

Claims

1. A device for the administration of powdered inhalation medicament contained initially in a medicament capsule having at least one aperture formed therein, said device comprising:

a swirl chamber adapted to receive the medicament capsule;

a mouthpiece communicating with the swirl chamber and separated therefrom by a grid;

at least one air inlet in tangential communication with the swirl chamber whereby air can be drawn through the device via the mouthpiece to cause a swirling air flow through the swirl chamber; and

a cover member, having a continuous substantially planar inner surface, provided on the base of the swirl chamber remote from the mouthpiece;

said cover being moveable between a first position in which a medicament capsule can be inserted in the swirl chamber and a second position in which such a medicament capsule can be retained in the swirl chamber and rotated upon air being drawn through the device, thereby dispensing a medicament contained in such a medicament capsule;

said device having no capsule piercing means.

2. A device according to claim 1 wherein the cover member is in hinged engagement with the base of the swirl chamber.

3. A device according to claim 1 which has two air inlets in tangential communication with the swirl chamber.

4. A device according to claim 1 which is provided with a mouthpiece cover.

5. A device according to claim 4, wherein the mouthpiece cover is adapted to cover the mouthpiece and at least one air inlet communicating with the swirl chamber.

6. A device according to claim 5, wherein the mouthpiece cover is provided with at least one protruding element adapted to cover at least one air inlet.

7. A device as claimed in claim 1 in which a medicament capsule containing powdered inhalation medicament and having at least one aperture formed therein is retained in the swirl chamber.

8. A device as claimed in claim 1 wherein the at least one or each air inlet tapers towards the swirl chamber.

9. A device as claimed in claim 1 which has a plurality of air inlets spaced at regular intervals around the swirl chamber.

10. A method for administering a powdered inhalation medicament comprising:

inserting a capsule having at least one aperture formed therein and containing a powdered inhalation medicament into a device having a swirl chamber adapted to receive the medicament capsule, said device further having a mouthpiece communicating with the swirl chamber, the swirl chamber having an air inlet positioned tangentially to the swirl chamber and in communication with the mouthpiece, such that air drawn through the device via the mouthpiece creates a circumferential stream through the chamber which causes the capsule to rotate; and

drawing an air stream through the swirl chamber in the direction of the mouthpiece causing the capsule to rotate in the swirl chamber and dispense the medicament contained through the aperture into the air stream and thence, into the mouthpiece;

said device having no capsule piercing means.

11. The method of claim 10 wherein the capsule is cylindrical.