Method of making a stent-graft covered with expanded polytetrafluoroethylene

• US 5,788,626 A
• Filed: 11/18/1996
• Issued: 08/04/1998
• Est. Priority Date: 11/21/1995
• Status: Expired due to Term

• Current Assignee: Lifeport Sciences LLC (Acacia Research Corporation)
• Original Assignee: Schneider Electric SE
• Inventors: Thompson, Paul J.
• Primary Examiner(s): Prebilic, Paul B.
• Application Number:
  US08/751,884
• Time in Patent Office: 624 Days
• Field of Search: 623/1, 623/12, 623/36
• US Class Current: 623/1.15
• CPC Class Codes: A61F 2/06 Blood vessels
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2002/072 Encapsulated stents, e.g. wire or whole stent embedded in lining
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2210/0057 stretchable
• CPC Class Codes: A61F 2230/0078 hyperboloidal
• CPC Class Codes: A61F 2250/0028 differing in fibre orientations
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61F 2250/0063 Nested prosthetic parts
• CPC Class Codes: A61L 31/10 Macromolecular materials
• CPC Class Codes: B29C 55/22 of tubes B29C61/08 takes precedence
• CPC Class Codes: B29D 23/001 Pipes; Pipe joints pleated hoses B29D23/18
• CPC Class Codes: B29K 2027/18 PTFE, i.e. polytetrafluorethene , e.g. ePTFE, i.e. expanded polytetrafluorethene
• CPC Class Codes: B29K 2995/0051 mono-axially
• CPC Class Codes: B29K 2995/0053 bi-axially
• CPC Class Codes: C08L 27/18 Homopolymers or copolymers or tetrafluoroethene

Abstract

The expandable stent-graft generally defines a cylindrical lumen made from a stent having a discontinuous wall that is at least substantially covered with an expanded polytetrafluoroethylene material. The expanded polytetrafluoroethylene covering may be a biaxially oriented, expanded polytetrafluoroethylene material having nodules and longitudinal and circumferential fibrils or a uniaxially oriented, expanded polytetrafluoroethylene material. The expandable stent-graft expands and compresses in association with the stent structure as it is contracted and expanded.

Claims

1. A method of making an expandable prosthesis comprising:

(a) providing a self-expanding braided stent having a longitudinal orientation in an at least partially radially expanded state;

(b) providing at least one layer of expanded polytetrafluoroethylene having a longitudinal orientation and a first average longitudinal inter-nodule distance in a free state;

(c) longitudinally compressing the layer of expanded polytetrafluoroethylene so that the resulting longitudinally compressed layer has a second average longitudinal inter-nodule distance which is less than the first average longitudinal inter-nodule distance; and

(d) affixing the longitudinally compressed layer of expanded polytetrafluoroethylene to the self-expanding braided stent in the at least partially radially expanded state such that the longitudinal orientations of the stent and layer of expanded polytetrafluoroethylene substantially correspond with one another.

2. The method of claim 1 wherein the first average longitudinal inter-nodule distance is between about 5 and about 150 microns, and the second average longitudinal inter-nodule distance is between about 0 and about 50 microns.

3. The method of claim 2 wherein the first average longitudinal inter-nodule distance is between about 20 and about 60 microns, and the second average longitudinal inter-nodule distance is between about 5 and about 45 microns.

4. The method of claim 3 wherein the second average inter-nodule distance is between about 20 and about 30 microns.

5. The method of claim 1 wherein an average circumferential inter-nodule distance of the expanded polytetrafluoroethylene in the free state is between about 5 microns and about 150 microns, and an average circumferential inter-nodule distance of the expanded polytetrafluoroethylene in the at least partially radially expanded state is between about 75 and about 150 microns.

6. The method of claim 5 wherein the average circumferential inter-nodule distance of the expanded polytetrafluoroethylene in the at least partially radially expanded state is between about 80 and about 140 microns.

7. The method of claim 6 wherein the average circumferential inter-nodule distance of the expanded polytetrafluoroethylene in the at least partially radially expanded state is between about 80 and about 120 microns.

8. The method of claim 1 wherein the second average longitudinal inter-nodule distance is between about 0 and 99 percent of the first average longitudinal inter-nodule distance.

9. The method of claim 8 wherein the second average longitudinal inter-nodule distance is between about 20 and about 50 percent of the first average longitudinal inter-nodule distance.

10. The method of claim 1 wherein the expanded polytetrafluoroethylene is selected from the group consisting of biaxially oriented expanded polytetrafluoroethylene and uniaxially oriented expanded polytetrafluoroethylene.