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Methods and compositions for inhibiting cell proliferative disorders

  • US 5,789,427 A
  • Filed: 03/07/1995
  • Issued: 08/04/1998
  • Est. Priority Date: 03/07/1994
  • Status: Expired due to Term
First Claim
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1. A compound having the chemical formula:

  • ##STR22## or a pharmaceutically acceptable salt thereof, wherein R1, R2, and R3 are each independently selected from the group consisting of alkyl, alkenyl, alkynyl, alkoxy, alkylaryl, OH, amine, thioether, SH, halogen, hydrogen, NO2 and NH2 ;

    Y is either nothing, --C(CN)═

    C--, -alkyl- or --NH-alkyl-; and

    R5 is either CN or aryl;

    provided that if R5 is aryl and said aryl is phenyl, then a) R1, R2, and R3 are not alkoxy or OH, and b) at least one of R1, R2, and R3 is not hydrogen.

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