Implanted cardiac device with means for classifying patient condition

• US 5,792,197 A
• Filed: 04/16/1997
• Issued: 08/11/1998
• Est. Priority Date: 04/29/1996
• Status: Expired due to Term

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Inventors: Nappholz, Tibor A.
• Primary Examiner(s): Getzow, Scott M.
• Application Number:
  US08/842,740
• Time in Patent Office: 482 Days
• Field of Search: 607/17, 607/18, 607/19, 607/20, 607/21, 607/22, 607/23, 607/24, 607/25, 607/4, 600/509, 600/510, 600/508
• US Class Current: 607/17
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance
• CPC Class Codes: A61N 1/36557 controlled by chemical substances in blood

Abstract

An implantable rate responsive pacemaker uses the physiological demand parameter to determine the classification of the patient (i.e., his degree of congestive heart failure). For this purpose, the parameter is monitored for extended time periods (i.e., several days) to determine the levels for said parameter corresponding to different levels of physical activity, such as maximum physical activity or rest. The variation in these levels is then translated into corresponding classification (0-IV) using a preselected criteria.

Claims

1. An implantable rate responsive pacemaker comprising:

a sensor for sensing intrinsic cardiac events and generating a corresponding sensed signal;

a pacing generator generating pacing signals in response to commands;

a metabolic demand sensor for sensing a physiological demand of the patient from a physiological characteristic, and generating in response a metabolic indicated pacing parameter;

a controller receiving said sensed signal and said metabolic indicated pacing parameter and generating said commands; and

a classifier for generating an index indicative of a degree of congestive heart failure in said patient, said classifier including means for analyzing said physiological demand.

2. The pacemaker of claim 1 wherein said physiological demand corresponds to a peak oxygen consumption of said patient during exercise.

3. The pacemaker of claim 2 wherein said physiological demand is a minute volume.

4. The pacemaker of claim 3 wherein said analyzer includes a logic circuit for determining a variation in said minute volume responsive to different levels of physical activity, said index being related to said variation.

5. The pacemaker of claim 4 wherein said variation is a ratio between a peak minute volume corresponding to a peak exercise and a rest minute volume corresponding to resting.

6. A rate responsive implantable pacemaker comprising:

an intrinsic sensor for sensing intrinsic cardiac activity in a patient'"'"'s heart, said intrinsic sensor generating in response sensed signals;

a pace generator for generating pacing signals in response to pacing commands;

a physiological sensor for sensing a metabolic demand of said patient based on a physiological characteristic of the patient;

a mapping circuit for mapping said metabolic demand into a corresponding metabolic pacing parameter;

a patient classifier for generating an indicia corresponding to a degree of congestive heart failure in a patient from said metabolic demand; and

a controller receiving said sensed signals, said metabolic pacing parameter and generating said pacing commands.

7. The pacemaker of claim 6 wherein said controller receives said indicia and uses said indicia to generate said pacing commands.

8. The pacemaker of claim 6 further comprising a memory for storing said indicia.

9. The pacemaker of claim 6 wherein said physiological characteristic is one of minute volume,QT interval and cardiac contractibility.

10. The pacemaker of claim 6 wherein said physiological sensor senses a minute volume.

11. The pacemaker of claim 10 wherein said patient classifier includes an accumulator for collecting the minute volume levels corresponding to various levels of exercise by said patient.

12. The pacemaker of claim 11 wherein said classifier includes a first accumulator for accumulating a maximum minute volume corresponding to periods of maximum exercise and a second accumulator for accumulating a rest minute volume corresponding to periods of minimum exercise.

13. The pacemaker of claim 12 wherein said accumulators accumulate said minute volumes for extended time periods ranging in the order of 30 days.

14. The pacemaker of claim 12 wherein said classifier generates said indicia based on a variation of said maximum and rest minute volumes.

15. The pacemaker of claim 14 wherein said classifier generates said indicia as a function of a ratio of said maximum and rest minute volumes.

16. The pacemaker of claim 15 wherein said classifier includes a translator for translating said ratio into a corresponding patient classification.

17. A method of determining the CHF classification of a patient comprising the steps of:

measuring a physiological parameter related to the metabolic demand;

determining a variation of said parameter as a function of various levels of physical activity; and

correlating said variation to a particular degree of classification.

18. The method of claim 17 wherein said step of measuring includes measuring a minute volume.

19. The method of claim 17 wherein said variation is a ratio between a high level physiological parameter corresponding to a high level exercise and a low level physiological parameter.

20. The method of claim 17 wherein said patient has an implant rate response pacemaker, said pacemaker including a metabolic sensor for sensing said physiological parameter and a controller for generating pacing pulses corresponding to said physiological parameter and another parameter comprising the step of generating said another parameter based on said degree of classification.

21. The method of claim 20 wherein said another parameter is a peak pacing rate.