Systems and methods for making time-sequential measurements of biopotentials sensed in myocardial tissue
First Claim
1. An element for generating a composite signal derived from biopotentials sensed in myocardial tissue comprisinga plurality of sensors,first means for inputting a first set of signals comprising a plurality of biopotentials sensed in myocardial tissue using a first group of the sensors during a first time interval,second means for inputting a second set of signals comprising a plurality of bipotentials sensed in myocardial tissue during a second time interval sequentially after the first time interval using a second group of the sensors having at least one common sensor that is part of the first group and other sensors that are not part of the first group, at least one of the biopotentials in the first set of signals being sensed in the first time interval and not in the second time interval, and at least one of the biopotenial in the second set of signals being sensed in the second time interval and not in the first time interval, andthird means for time aligning the first and second sets of signals using biopotentials sensed in myocardial tissue by the at least one common sensor, thereby generating the composite signal arranged for analysis as if all biopotentials were sensed during a common time interval, whereby-the composite signal provides a diagnostic indicator.
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Abstract
Analog or digital systems and methods generate a composite signal derived from a biological event in a time-sequential fashion. The systems and methods input a first set of signals derived from a biological event using a first group of sensors during a first time interval. The systems and methods input a second set of signals derived from the biological event during a second time interval sequentially after the first time interval using a second group of sensors. The second group of sensors has at least one common sensor that is part of the first group and other sensors that are not part of the first group. The systems and methods time align the first and second sets of signals using the signals sensed by the at least one common sensor, thereby generating the composite signal. The systems and methods time align by shifting the first and second sets of signals either with or without computing a time difference between them.
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Citations
42 Claims
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1. An element for generating a composite signal derived from biopotentials sensed in myocardial tissue comprising
a plurality of sensors, first means for inputting a first set of signals comprising a plurality of biopotentials sensed in myocardial tissue using a first group of the sensors during a first time interval, second means for inputting a second set of signals comprising a plurality of bipotentials sensed in myocardial tissue during a second time interval sequentially after the first time interval using a second group of the sensors having at least one common sensor that is part of the first group and other sensors that are not part of the first group, at least one of the biopotentials in the first set of signals being sensed in the first time interval and not in the second time interval, and at least one of the biopotenial in the second set of signals being sensed in the second time interval and not in the first time interval, and third means for time aligning the first and second sets of signals using biopotentials sensed in myocardial tissue by the at least one common sensor, thereby generating the composite signal arranged for analysis as if all biopotentials were sensed during a common time interval, whereby-the composite signal provides a diagnostic indicator.
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8. A system for generating a composite signal derived from biopotentials sensed in myocardial tissue comprising
multiple sensors for sensing biopotentials in myocardial tissue comprising a first sensor group and a second sensor group having at least one common sensor that is part of the first group and other sensors that are not part of the first group, and a processing element coupled to the multiple sensors and operative for creating the composite signal by steps comprising (i) generating a first set of signals by conditioning the first sensor group to sense in myocardial tissue a plurality of biopotentials during a first time interval, (ii) generating a second set of signals by conditioning the second sensor group to sense in myocardial tissue a plurality of biopotentials during a second time interval, the second time interval being sequentially after the first time interval, at least one of the biopotentials in the first set of signals being sensed in the first time interval and not in the second time interval, and at least one of the biopotentials in the second set of signals being sensed in the second time interval and not in the first time interval, (iii) time aligning the first and second sets of signals using the biopotentials sensed in myocardial tissue by the at least one common sensor, thereby generating a composite signal arranged for analysis as if all biopotentials were sensed during a common time interval, whereby the composite signal provides a diagnostic indicator.
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16. A system for analyzing biopotential morphologies in myocardial tissue comprising
multiple electrodes for sensing biopotentials in a myocardial tissue region comprising a first electrode group and a second electrode group having at least one common electrode that is part of the first group and other electrodes that are not part of the first group, a processing element coupled to the multiple electrodes and operative for creating a composite sample of biopotentials by steps comprising (i) generating a first set of signals-by conditioning the first electrode group to sense a plurality of biopotentials occurring in the myocardial tissue region during a biopotential generating event during a first time interval, (ii) generating a second set of signals by conditioning the second electrode group to sense a plurality of biopotentials occurring in the myocardial tissue region during a second time interval of the biopotential generating event, the second time interval being sequentially after the first time interval, at least one of the biopotentials in the first set of signals being sensed in the first time interval and not in the second time interval, and at least one of the biopotentials in the second set of signals being sensed in the second time interval and now in the first time interval, (iii) time aligning the first and second sets of signals using biopotentials sensed by the at least one common electrode, thereby creating the composite biopotential sample arranged for analysis as if all biopotentials were sensed during a common time interval, whereby the composite signal provides a diagnostic indicator.
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22. An apparatus for processing biopotentials sensed first, second, and third signal sensors in myocardial tissue, the apparatus comprising
first and second signal processing channels, and a processing element coupled to the processing channels comprising first means for coupling the first and second signal sensors to the first and second processing channels during a first time interval to record a first set of signals comprising a plurality of biopotentials sensed in myocardial tissue, second means for coupling the first and third signal sensors to the first and second processing channels during a second time interval different than the first time interval to record a second set of signals comprising a plurality of biopotentials sensed in myocardial tissue, at least one of the biopotentials in the first set of signals being sensed in the first time interval and not in the second, time interval, and at least one of the biopotentials in the second set of signals being sensed in the-second time interval and not in the first time interval, third means for time aligning the first and second sets of signals by using biopotentials sensed by the first signal sensor to create a composite set of signals comprising the biopotentials sensed by the first, second, and third sensors arranged for analysis as if all biopotential were recorded during a common time interval, whereby the composite set provides a diagnostic indicator.
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29. A method for generating a composite signal derived from biopotentials sensed in myocardial tissue comprising the steps of
inputting a first set of signals comprising a plurality of biopotentials sensed in myocardial tissue by a first group of sensors during a first time interval, inputting a second set of signals comprising a plurality of biopotentials sensed in myocardial tissue during a second time interval sequentially after the first time interval using a second group of sensors having at least one common sensor that is part of the first group and other sensors that are not part of the first group, at least one of the biopotentials in the first set of signals being sensed in the first time interval and not in the second time interval, and at least one of the biopotentials in the second set of signals being sensed in the second time interval and not in the first time interval, and time aligning the first and second sets of signals using biorotentials sensed by the at least one common sensor, thereby generating the composite signal arranged for analysis as if all biopotentials were recorded during a common time interval whereby the composite signal provides a diagnostic indicator.
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36. A method using first and second processing channels for processing biopotential signals sensed in myocardial tissue by first, second, and third signal sensors, the method comprising the steps of
coupling the first and second signal sensors to the first and second processing channels during a first time interval to record a first set of biopotential signals, coupling the first and third signal sensors to the first a second processing channels during a second time interval different than the first time interval to record a second set of biopotential signals, at least one of the biopotential signals in the first set being sensed in the first time interval and not in the second time interval, and at least one of the biopotential signals in the second set being sensed in the second time interval and not in the first time interval, and time aligning the first and second sets of biopotential signals based upon the biopotential signals sensed by the first signal sensor to create a composite set of biopotential signals comprising the biopotential signals sensed by the first, second, and third sensors arranged for analysis as if all biopotential signals were recorded during a common time interval, whereby the composite set of biopotential signals provides a diagnostic indicator.
Specification