Syringe assembly and syringe stopper

• US 5,795,337 A
• Filed: 04/10/1996
• Issued: 08/18/1998
• Est. Priority Date: 02/14/1994
• Status: Expired due to Term

• Current Assignee: Becton, Dickinson & Co
• Original Assignee: Becton, Dickinson & Co
• Inventors: Grimard, Jean Pierre
• Primary Examiner(s): Coggins, Wynn Wood
• Assistant Examiner(s): NGUYEN, ANH TUAN TUONG
• Application Number:
  US08/630,338
• Time in Patent Office: 860 Days
• Field of Search: 604/218, 604/219, 604/222, 604/228, 604/230, 604/82, 604/90, 604/110, 604/191, 604/195
• US Class Current: 604/222
• CPC Class Codes: A61M 2005/3132 having flow passages for injection agents at the distal end of the barrel to bypass a sealing stopper after its displacement to this end due to internal pressure increase
• CPC Class Codes: A61M 2005/31516 reducing dead-space in the syringe barrel after delivery
• CPC Class Codes: A61M 5/31511 Piston or piston-rod constructions, e.g. connection of piston with piston-rod A61M5/5066 takes precedence

Abstract

A syringe stopper for use in a syringe barrel having a substantially cylindrical body comprises a piston-like stopper body for slidable fluid-tight engagement inside the barrel of the syringe. The body includes a distal end, a proximal end and a longitudinal axis therethrough. A distally directed, conically-shaped projection is positioned on the distal end of the stopper body. At least one elongate discontinuity, running along the conically-shaped projection, is provided. The discontinuity includes a first end on the conically-shaped projection and extends radially outwardly therefrom to a second end, as viewed from the distal end of the stopper. The discontinuity may be in the form of a raised rib or a recessed groove.

Claims

1. A syringe stopper made of a resilient material for use in a syringe barrel having a substantially cylindrical body comprising:

a piston-like stopper body for slidable fluid-tight engagement inside the barrel of the syringe, said stopper body having an outside diameter, a distal end, a proximal end and a longitudinal axis therethrough;

a conically-shaped projection on said distal end of said stopper body and projecting outwardly therefrom, said conically-shaped projection defining a base as it intersects said distal end of stopper body, said base having a base diameter less than said outside diameter of said stopper body to provide an exposed portion of said stopper body between the base of the conically-shaped projection and the distal end the stopper body; and

a plurality of elongated discontinuities running along said conically-shaped projection in the form of raised ribs and continuing past the base of the conically-shaped projection into the exposed portion along the distal end of the stopper body, said raised ribs each having a first end on said conically-shaped projection and extending radially outwardly from the longitudinal axis of the stopper body to a second end disposed past the intersection of said base diameter and said distal end of the stopper body on said exposed portion of the distal end of said stopper body.

2. The syringe stopper of claim 1 in combination with a syringe barrel, said barrel having an open proximal end, a distal end and a cylindrical body portion therebetween defining a chamber for retaining liquid, said stopper body positioned in fluid-tight engagement inside said barrel so that said distal end of said stopper faces said distal end of said barrel,

said distal end of said barrel having an aperture therethrough in fluid communication with said chamber.

3. The combination of claim 2 wherein said syringe barrel is made at least partially of glass.

4. The combination of claim 2 further including an elongate needle cannula having a distal end, a proximal end and a lumen therethrough, said proximal end of said needle cannula being connected to said distal end of said barrel so that said lumen is in fluid communication with said chamber.

5. The combination of claim 4 wherein said needle cannula is irremovably connected to said barrel.

6. The syringe stopper of claim 1 wherein said stopper body includes at least two annular ribs and a recess therebetween, said ribs having an outside diameter greater than the diameter of said recess.

7. The syringe stopper of claim 1 wherein said raised ribs are substantially straight when viewed from said distal end of said stopper body.

8. The syringe stopper of claim 1 wherein said raised ribs are curvilinearly shaped when viewed from said distal end of said stopper body.

9. The syringe stopper of claim 1 wherein said raised ribs comprises four raised ribs.

10. The syringe stopper of claim 1 wherein said base diameter is within the range of thirty percent to eighty percent of the outside diameter of said stopper body.

11. The syringe stopper of claim 1 wherein said base diameter is within the range of forty percent to sixty percent of the outside diameter of said stopper body.

12. The syringe stopper of claim 1 further including an annular rib at said distal end and an annular rib at said proximal end of said stopper body, said stopper body having an annular recess between said ribs, said recess having a diameter of less than the diameter of said ribs, said rib on said distal end further including at least one groove for allowing fluid communication therethrough.

13. The syringe stopper of claim 12 wherein said at least one groove is a plurality of grooves.

14. The syringe stopper of claim 12 wherein said groove is positioned angularly with respect to the longitudinal axis of said stopper body.

15. The syringe stopper of claim 14 wherein said at least one groove is oriented at an angle within the range of about 30°

to 80°

with respect to said longitudinal axis.

16. The syringe stopper of claim 1 further including means for engaging a rigid plunger rod on said proximal end of said stopper body.

17. The syringe stopper of claim 16 wherein said means for engaging includes a threaded recess in said proximal end of said stopper body.

18. The syringe stopper of claim 16 wherein said means for engaging includes a cavity in the proximal end of said stopper body having a neck or reduced diameter portion at said proximal end of said stopper body.

19. The syringe stopper of claim 16 further including a rigid elongate plunger rod having a distal end and a proximal end, said distal end of said plunger rod being connected to said proximal end of said stopper body.

20. The syringe stopper of claim 1 wherein said resilient material is selected from the group consisting of natural rubber, synthetic rubber, thermoplastic elastomers, and combinations thereof.

21. The syringe stopper of claim 1 wherein said stopper body includes at least a first annular rib at the distal end and a second annular rib at the proximal end, with said second annular rib being spaced apart from the first annular rib to form a recess located therebetween to provide a stable fluid-tight seal between the stopper body and the syringe barrel.