Inhaler

• US 5,797,392 A
• Filed: 01/22/1997
• Issued: 08/25/1998
• Est. Priority Date: 01/22/1996
• Status: Expired due to Term

• Current Assignee: Acerus Biopharma, Inc.
• Original Assignee: Direct-Haler A/S (Keldmann Innovation A/S)
• Inventors: Keldmann, Erik, Reipur, John
• Primary Examiner(s): Lewis, Aaron J.
• Assistant Examiner(s): Deane, Jr., William J.
• Application Number:
  US08/785,960
• Time in Patent Office: 580 Days
• Field of Search: 128/207.14, 128/911, 128/912, 128/203.12, 128/203.15, 128/203.23, 604/24, 604/26, 604/37, 604/58, 604/59, 604/60, 604/142, 604/117
• US Class Current: 128/203.15
• CPC Class Codes: A61M 15/0028 using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
• CPC Class Codes: A61M 15/0045 using multiple prepacked dosages on a same carrier, e.g. blisters
• CPC Class Codes: A61M 2205/6081 Colour codes

Abstract

An inhaler comprises a tubular body in which an air flow passage is defined. A single dose of an active, inhalable, particulate substance is arranged within the air flow passage and is sealed or closed in relation to the ambient atmosphere by closure means, such as removable caps, a section of the flow passage extending from a free mouthpiece end of the tubular body along a major part of the total length of the flow passage is preferable 7-35 mm², for example about 20 mm². The inhaler may be adapted to be used only once, and the tubular body of the inhaler may be a length of a simple tube similar to a drinking straw.

Claims

1. An inhaler comprising:

a one piece tubular body, which has a mouthpiece section and is intended to be used only once, and which defines an air flow passage therein, the tubular body having substantially rectilinear sections, at least one intermediate bendable section comprising peripherally extending corrugations; and

a single dose only of an active, inhalable, particulate substance being arranged within the air flow passage, said dose being sealed or closed in relation to an ambient atmosphere by closure means which are to be removed or opened by a user prior to use, and a cross-sectional area of the flow passage defined in the tubular body being unobstructed and not exceeding 75 mm².

2. An inhaler according to claim 1, wherein the tubular body comprises a pair of corrugated bendable sections, which are spaced by a non-corrugated rectilinear tubular section, so that the tubular body may be bent into a substantial S-shape.

3. An inhaler according to claim 1, wherein the corrugations of the corrugated bendable section are of the type which in an axial sectional view defines relatively sharp valleys and peaks.

4. An inhaler according to claim 3, wherein the corrugations are substantially saw tooth shaped in an axial sectional view.

5. An inhaler according to claim 1, wherein the cross-sectional area of the flow passage does not exceed 70 mm².

6. An inhaler according to claim 5, wherein the cross-sectional area of the flow passage does not exceed 50 mm².

7. An inhaler according to claim 6, wherein the cross-sectional area of the flow passage is 7-35 mm².

8. An inhaler according to claim 1, wherein the flow passage has a substantially circular cross-section, the inner diameter of the flow passage being substantially the same along the length of the tubular body.

9. An inhaler according to claim 8, wherein the inhaler is formed similar to a drinking straw.

10. An inhaler according to claim 1, wherein the bottoms of the corrugations are provided with codes for assisting in obtaining a bend suitable for the individual user.

11. An inhaler according to claim 1, wherein the mouthpiece section has a length so as to extend during use from the teeth of the user to a position adjacent to the root of the user'"'"'s tongue.

12. An inhaler according to claim 1, further comprising a bite piece formed on the outer surface of the tubular body for engaging with the upper jaw teeth of the user so as to position the inhaler in the oral cavity of the user.

13. An inhaler according to claim 12, wherein the bite piece is removably mounted on the tubular body.

14. An inhaler according to claim 12, wherein the shape of the bite piece is adapted to the teeth of the individual user.

15. An inhaler according to claim 1, wherein the tubular body is moveable from a retracted storage condition to an extended condition of use.

16. An inhaler according to claim 15, wherein the tubular body is provided with peripheral corrugations along a major part of its length so as to allow longitudinal stretching of the tubular body.

17. An inhaler according to claim 1, wherein the closure means comprise a pair of cap members removably mounted at opposite ends of the tubular body.

18. An inhaler according to claim 1, wherein the free ends of the tubular body are positioned closely adjacent, said free ends being closed by a common removable closure member.

19. An inhaler according to claim 17, wherein at least one of the cap members is made from a transparent material.

20. An inhaler according to claim 1, wherein the tubular body is at least partly made from a transparent material.

21. An inhaler according to claim 1, wherein the mouthpiece section of the tubular body is adapted to be inserted into a nostril of a user.

22. An inhaler according to claim 21 comprising a pair of tubular bodies and a connecting part for interconnecting the same, said one end or mouthpiece end of said pair of tubular bodies being arranged in spaced relationship so that said ends may be inserted into the nostrils of a user.

31. An inhaler according to claim 7, wherein the cross-sectional areas of the flow passage is about 20 mm².

23. An inhaler comprising:

a one piece tubular body, which has a mouthpiece section and is intended to be used only once, and which defines an air flow passage therein, the tubular body having a pair of substantially rectilinear sections and an intermediate curved section defining an obtuse angle between the rectilinear sections; and

a single dose only of an active, inhalable, particulate substance being arranged within the air flow passage, said dose being sealed or closed in relation to a ambient atmosphere by closure means which are to be removed or opened by a user prior to use and a cross-sectional area of the flow passage defined in the tubular body being unobstructed and not exceeding 75 mm².

24. An inhaler according to claim 23, wherein the curved section of the tubular body comprises peripherally extending corrugations.

25. An inhaler according to claim 24, wherein the corrugations of the corrugated curved section are of the type which in an axial sectional view defines relatively sharp valleys and peaks.

26. An inhaler according to claim 25, wherein the corrugations are substantially saw tooth shaped in an axial sectional view.

27. An inhaler according to claim 23, wherein the cross-sectional area of the flow passage does not exceed 70 mm².

28. An inhaler according to claim 27, wherein the cross-sectional area of the flow passage does not exceed 50 mm².

29. An inhaler according to claim 28, wherein the cross-sectional area of the flow passage is 7-35 mm².

30. An inhaler according to claim 29, wherein the cross-sectional area of the flow passage is about 20 mm².

32. An inhaler according to claim 23, wherein the flow passage has a substantially circular cross-section, the inner diameter of the flow passage being substantially the same along the length of the tubular body.

33. An inhaler according to claim 29, wherein the inhaler is formed similar to a drinking straw.

34. An inhaler according to claim 23, further comprising means for imparting to air flowing through the flow passage a rotational movement about the longitudinal axis of the flow passage.

35. An inhaler according to claim 23, wherein the mouthpiece section has a length so as to extend during use from the teeth of the user to a position adjacent to the root of the user'"'"'s tongue.

36. An inhaler according to claim 23, further comprising a bite piece formed on the outer surface of the tubular body for engaging with the upper jaw teeth of the user so as to position the inhaler in the oral cavity of the user.

37. An inhaler according to claim 36, wherein the bite piece is removably mounted on the tubular body.

38. An inhaler according to claim 37, wherein the shape of the bite piece is adapted to the teeth of the individual user.

39. An inhaler according to claim 23, wherein the closure means comprise a pair of cap members removably mounted at opposite ends of the tubular body.

40. An inhaler according to claim 39, wherein the free ends of the tubular body are positioned closely adjacent, said free ends being closed by a common removable closure member.

41. An inhaler according to claim 39, wherein at least one of the cap members is made from a transparent material.

42. An inhaler according to claim 23, wherein the tubular body is at least partly made from a transparent material.

43. An inhaler according to claim 23, wherein the mouthpiece section of the tubular body is adapted to be inserted into a nostril of a user.

44. An inhaler according to claim 43 comprising a pair of tubular bodies and a connecting part for interconnecting the same, said one end or mouthpiece end of said pair of tubular bodies being arranged in spaced relationship so that said ends may be inserted into the nostrils of a user.