Sleep apnea screening and/or detecting apparatus and method

• US 5,797,852 A
• Filed: 06/07/1995
• Issued: 08/25/1998
• Est. Priority Date: 02/04/1993
• Status: Expired due to Fees

• Current Assignee: NovaSom, Inc. (BioSerenity SAS)
• Original Assignee: Local Silence, Inc.
• Inventors: Hung, Chin N., Karakasoglu, Ahmet, Matouk, Anthony F., Grotte, Lawrence C.
• Primary Examiner(s): Lacyk, John P.
• Assistant Examiner(s): CARTER, RYAN CHRISTOPHER
• Application Number:
  US08/472,441
• Time in Patent Office: 1,175 Days
• Field of Search: 128/716, 128/633, 128/670-671, 128/706, 128/715, 128/721, 128/719
• US Class Current: 600/529
• CPC Class Codes: A61B 5/4818 Sleep apnoea
• CPC Class Codes: A61B 5/725 using specific filters therefor, e.g. Kalman or adaptive filters A61B5/316 take precedence
• CPC Class Codes: A61B 5/7475 User input or interface means, e.g. keyboard, pointing device, joystick
• CPC Class Codes: A61B 7/003 Detecting lung or respiration noise
• CPC Class Codes: A61F 5/56 Devices for preventing snoring by influencing the respiratory system by gas treatment A61M16/00
• CPC Class Codes: G10K 2210/10 Applications
• CPC Class Codes: G10K 2210/108 Communication systems, e.g. where useful sound is kept and noise is cancelled
• CPC Class Codes: G10K 2210/116 Medical; Dental
• CPC Class Codes: G10K 2210/12 Rooms, e.g. ANC inside a room, office, concert hall or automobile cabin
• CPC Class Codes: G10K 2210/3221 Headrests, seats or the like, for personal ANC systems

Abstract

Sleep apnea screening and/or detection apparatus for use by a patient breathing through the nose and/or mouth and producing an air flow into and out of the lungs of the patient and creating audible sounds. It is comprised of a first microphone positioned in the vicinity of the patient'"'"'s nose and mouth and out of contact therewith to pick up audible sounds created by breathing of the patient and providing a first electrical analog signal. A second microphone is provided which is positioned near the patient for picking up ambient noise in the vicinity of the patient and providing a second electrical analog signal, an active noise controller is provided for combining the first and second electrical analog signals to provide a third electrical signal for generating a fourth electrical signal providing a waveform which is closely correlated with the air flow of the patient. A classifier is provided for classifying the electrical waveform provided by the fourth electrical signal to determine when a disordered breathing event has occurred.

Claims

1. A sleep apnea screening and/or detection apparatus for use by a patient having lungs and a nose and mouth in communication with the lungs and breathing through the nose and/or mouth and producing an air flow into and out of the lungs and creating audible sounds comprising a first microphone adapted to be positioned adjacent the patient'"'"'s nose and/or mouth to pick up directly audible breathing sounds created by breathing of the patient and providing a first electrical analog signal, a second microphone adapted to be positioned near the patient but spaced from the first microphone and out of contact with the patient for picking up ambient audible noise in the vicinity of the patient and providing a second electrical analog signal, means operating on and combining the first and second electrical analog signals to provide a third electrical signal, means operating on the third electrical signal for generating a fourth electrical signal providing a waveform which is closely correlated with the air flow of the patient and electrical classifier means for classifying the electrical waveform provided by the fourth electrical signal to determine when a disordered breathing event has occurred.

4. Apparatus in claim 1 wherein said electrical classifier means includes a peak detector for ascertaining a nominal peak value for the peaks in the waveform of the fourth electrical signal, a threshold detector having a predetermined threshold value which is a percentage of the nominal peak value for ascertaining when the fourth electrical signal reaches said predetermined value, time duration counting means for measuring elapsed time connected to the threshold detector for ascertaining the time which elapsed after the threshold detector detects a value which is less than the predetermined value and decision making means for ascertaining when the predetermined threshold has not been reached for a predetermined period of elapsed time to establish that a disordered breathing event has occurred.

6. Apparatus as in claim 1 further including a band-pass filter network for filtering the third electrical signal.

10. Apparatus as in claim 1 together with display means for displaying in real time the occurrence of a disordered breathing event of the patient.

2. A sleep apnea screening and/or detection apparatus for use by a patient having lungs and a nose and mouth in communication with the lungs and breathing through the nose and/or mouth and producing an air flow into and out of the lungs and creating audible sounds comprising a first microphone adapted to be positioned adjacent the patient'"'"'s nose and mouth and out of contact therewith to pick up audible sounds created by breathing of the patient and providing a first electrical analog signal, a second microphone adapted to be positioned near the patient for picking up ambient noise in the vicinity of the patient and providing a second electrical analog signal, means operating on and combining the first and second electrical analog signals to provide a third electrical signal, means operating on the third electrical signal for generating a fourth electrical signal providing a waveform which is closely correlated with the air flow of the patient and electrical classifier means for classifying the electrical waveform provided by the fourth electrical signal to determine when a disordered breathing event has occurred, said means operating on the third electrical signal including means for converting the third electrical signal to positive absolute values and sequentially integrating the positive absolute values of the third electrical signal with adjusted time constants to provide the fourth electrical signal.

3. Apparatus in claim 2 wherein said means for operating on the third electrical signal utilizes the formula

5. A sleep apnea screening and/or detection apparatus for use by a patient having lungs and a nose and mouth in communication with the lungs and breathing through the nose and/or mouth and producing an air flow into and out of the lungs and creating audible sounds comprising a first microphone adapted to be positioned adjacent the patient'"'"'s nose and mouth and out of contact therewith to pick up audible sounds created by breathing of the patient and providing a first electrical analog signal, a second microphone adapted to be positioned near the patient for picking up ambient noise in the vicinity of the patient and providing a second electrical analog signal, means operating on and combining the first and second electrical analog signals to provide a third electrical signal, means operating on the third electrical signal for generating a fourth electrical signal providing a waveform which is closely correlated with the air flow of the patient and electrical classifier means for classifying the electrical waveform provided by the fourth electrical signal to determine when a disordered breathing event has occurred, an analog-to-digital converter for receiving the first electrical analog signal and converting it to a first electrical digital signal, adaptive filter means for receiving the first electrical digital signal and selectively tapping the first electrical digital signal to provide a first electrical digital signal which is delayed in time, an analog-to-digital converter for converting the second electrical analog signal to a second electrical digital signal and delay means for delaying the second electrical digital signal so that the time-delay corresponds to the time-delay provided by the adaptive filter so that the first electrical digital signal and the second electrical signal are supplied substantially in unison in time to the means for combining the first and second electrical analog signals.

7. Apparatus in claim 5 wherein said band-pass filter network includes a plurality of band pass filters and means for selecting which of the plurality of band pass filters provides the greatest output.

8. Apparatus in claim 5 wherein said adaptive filter means includes a Motorola DSP56002 chip and in which the sampling frequency is 5.6 kilohertz and a range of taps from 50 to 200 is selected.

9. Apparatus as in claim 5 wherein the band-pass filter network has a spectrum of 200 Hz to 1500 Hz and wherein each band-pass filter has a band-pass of approximately 100 Hz.

11. Apparatus as in claim 9 wherein the display means includes means for cumulating in real terms all disordered breathing events of the patient over a predetermined period of time.

12. A method for screening and/or detection of sleep apnea in a patient having lungs and a nose and mouth in communication with the lungs and breathing through the nose and/or mouth and producing an air flow into and out of the lungs and creating audible sounds comprising detecting directly audible breathing sounds created at the patient'"'"'s mouth and/or nose and providing a first electrical analog signal in response thereto, detecting audible sounds in a space remote from the patient'"'"'s nose and mouth which represent ambient noise to provide a second analog electrical signal, operating on the first and second electrical analog signals and combining the first and second electrical analog signals to provide a third electrical digital signal in which unwanted ambient noise is reduced, utilizing the third electrical digital signal to generate a fourth electrical signal providing an electrical waveform that closely approximates the air flow of the patient and classifying the electrical waveform to determine when a disordered breathing event has occurred.

15. A method as in claim 12 wherein the step of classifying the electrical waveform includes ascertaining a nominal value for the peaks in the electrical waveform, detecting when the peaks in the electrical waveform are less than a predetermined percentage of the nominal value of peaks and ascertaining when the elapsed time during which a peak does not exceed a predetermined threshold to determine when a disordered breathing event has occurred.

16. A method as in claim 12 further comprising the step of counting in real time each disordered breathing event.

13. A method for screening and/or detection of sleep apnea in a patient having lungs and a nose and mouth in communication with the lungs and breathing through the nose and/or mouth and producing an air flow into and out of the lungs and creating audible sounds comprising detecting directly audible sounds in the vicinity of the patient'"'"'s mouth and/or nose and providing a first electrical analog signal in response thereto, detecting audible sounds in a remote space from the patient'"'"'s nose and mouth which represent ambient noise to provide a second analog electrical signal, operating on the first and second electrical analog signals and combining the first and second electrical analog signals to provide a third electrical digital signal in which unwanted ambient noise is reduced, utilizing the third electrical digital signal to generate a fourth electrical signal providing an electrical waveform that closely approximates the air flow of the patient and classifying the electrical waveform to determine when a disordered breathing event has occurred, the step of generating the fourth electrical signal to provide the electrical waveform being accomplished by sequentially integrating the third electrical signal with adjustable time constants.

14. A method as in claim 13 wherein the waveform is generated by converting the third electrical signal to positive absolute values and sequentially integrating the positive absolute values of the third electrical signal with adjusted time constants to provide the fourth electrical signal.

17. A method for screening and/or detection of sleep apnea in a patient having lungs and a nose and mouth in communication with the lungs and breathing through the nose and/or mouth and producing an air flow into and out of the lungs and creating audible sounds comprising detecting directly audible sounds in the vicinity of the patient'"'"'s mouth and/or nose and providing a first electrical analog signal in response thereto, detecting audible sounds in a remote space from the patient'"'"'s nose and mouth which represent ambient noise to provide a second analog electrical signal, operating on the first and second electrical analog signals and combining the first and second electrical analog signals to provide a third electrical digital signal in which unwanted ambient noise is reduced, utilizing the third electrical digital signal to generate a fourth electrical signal providing an electrical waveform that closely approximates the air flow of the patient and classifying the electrical waveform to determine when a disordered breathing event has occurred, further comprising the step of converting the first electrical analog signal to a digital signal and adaptively filtering the digital signal, converting the second electrical analog signal to a digital signal, delaying the second electrical signal so that the digital signal from the first electrical signal and the digital signal from the second electrical signal are combined at the same time to provide the third electrical signal.

18. A method as in claim 17 further comprising the step of filtering the third electrical signal in successive band passes to select a band through which the third electrical signal passes with a maximum output.