Helical embolization coil

• US 5,797,953 A
• Filed: 02/23/1996
• Issued: 08/25/1998
• Est. Priority Date: 03/18/1994
• Status: Expired due to Term

• Current Assignee: Cook Medical Technologies, LLC (Cook Group Incorporated)
• Original Assignee: Cook Incorporated (Cook Group Incorporated)
• Inventors: Tekulve, Kurt J.
• Primary Examiner(s): Buiz, Michael Powell
• Assistant Examiner(s): LEWIS, WILLIAM W
• Application Number:
  US08/609,767
• Time in Patent Office: 914 Days
• Field of Search: 606/191, 606/194, 606/195, 606/198, 606/200, 623/1, 623/12, 128/899
• US Class Current: 606/200
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61F 2/011 Instruments for their placement or removal
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/0091 helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section

Abstract

A conically helically shaped embolization coil (10) for occluding a blood vessel, aneurysm, and the like. The embolization coil includes a continuous platinum-tungsten alloy wire strand (11) wound into a longitudinally extending coil (12) having a plurality of tightly spaced turns (13). The longitudinally extending coil is wound into a conically helically shaped coil (15) with a plurality of radially expanding turns (16) that has spacing that increases proximally from the distal end (29) of the coil. Distal turn (17) of the radially expanding turns has a minor diameter (18) less than a minimum diameter (34) of a vessel (32) of which the embolization is to be positioned therein. Uncompressed proximal turn (19) of the radially expanding turns has a major diameter (20) greater than a maximum diameter (33) of the vessel in which the coil to be positioned. The conically helically shaped coil and particular diameter ensure that the coil is precisely positioned in a vessel lumen without longitudinal displacement of the delivery catheter. The coil is stress relieved and, in particular, heat treated by heating the coil to a stress relief temperature of the continuous wire strand and cooled to relieve residual stresses formed during the winding of the coil and to minimize the formation of new residual stresses formed during the cool down period of the heat treatment. Thrombogenic fibers (26) are positioned in the tightly spaced turns of the coil to attract thrombus and build up a mass that occludes the vessel lumen.

Claims

1. An embolization coil (10) comprising:

a continuous wire strand (11) wound into a longitudinally extending coil (12) having a plurality of tightly spaced turns (13), said longitudinally extending coil wound into a conically helically shaped coil (15) having a plurality of radially expanding turns (16), said radially expanding turns longitudinally overlapping each other, whereby said radially expanding turns longitudinally contact each other in response to blood flowing therethrough to occlude a vessel in which the embolization coil is positioned.

2. The embolization coil of claim 1 wherein said radially expanding turns include spacing (21) therebetween that increases proximally.

3. The embolization coil of claim 1 wherein said conically helically shaped coil is heat treated to relieve stresses that are formed when winding said longitudinally extending coil and said conically helically shaped coil.

4. The embolization coil of claim 1 wherein said continuous wire strand is comprised of a metallic alloy and wherein conically helically shaped coil is formed by the steps of:

winding said longitudinally extending coil around a longitudinally tapered mandril (23) with a plurality of minimally spaced turns (24), heating said conically helically shaped coil when wound around said longitudinally tapered mandril at a stress relief temperature of said metallic alloy for a first time period, and cooling said conically helically shaped coil when wound around said longitudinally tapered mandril from said stress relief temperature for a second time period greater than said first time period.

5. The embolization coil of claim 4 wherein the steps of forming said conically helically shaped coil further include selecting said longitudinally tapered mandril of a material (25) that remains substantially free of surface oxidation during heating and cooling of said conically helically shaped coil.

6. The embolization coil of claim 5 wherein said metallic alloy comprises at least one from a group consisting of platinum, stainless steel, iridium, palladium, tungsten, and gold.

7. The embolization coil of claim 1 wherein said conically helically shaped coil is heated at a stress relief temperature of said continuous wire strand for a first time period and then gradually cooled down from said stress relief temperature for a second time period greater than said first time period.

8. The embolization coil of claim 1 wherein said continuous wire strand comprises a metallic material (22) that is substantially free of surface oxidation.

9. The embolization coil of claim 1 further comprising thrombogenic fibers (26) positioned in said plurality of tightly spaced turns of said longitudinally extending coil.

10. An embolization coil (10) comprising:

a continuous wire strand (11) of a metallic alloy (22) wound into a longitudinally extending coil (12) having a plurality of tightly spaced turns (13), said longitudinally extending coil wound into a conically helically shaped coil (15) having a plurality of radially expanding turns, said conically helically shaped coil of said metallic alloy being stress relieved and substantially free of surface oxidation, said radially expanding turns longitudinally overlapping each other, whereby said radially expanding turns longitudinally contact each other in response to blood flowing therethrough to occlude a vessel in which the embolization coil is positioned.

11. The embolization coil of claim 10 wherein a distal turn (17) of said radially expanding turns has a minor diameter (18) less than a major diameter (20) of a proximal turn (19) of said radially expanding turns, said major diameter (20) being no greater than 30 mm.

12. The embolization coil of claim 10 wherein said radially expanding turns have a spacing (21) therebetween that increases from a distal turn (17) to a proximal turn (19) thereof.

13. The embolization coil of claim 10 wherein said conically helically shaped coil is formed by the steps of:

winding said longitudinally extending coil around a longitudinally tapered mandril (23) with a plurality of minimally spaced turns (24) and heat treating said conically helically shaped coil when wound around said longitudinally tapered mandril to relieve residual stresses formed therein.

14. The embolization coil of claim 10 wherein said metallic alloy includes at least one from a group consisting of platinum, stainless steel, iridium, palladium, tungsten, and gold.

15. The embolization coil of claim 14 wherein said conically helically shaped coil is formed by the steps of:

winding said longitudinally extending coil around a longitudinally tapered mandril (23) and heating said conically helically shaped coil at a stress relief temperature of said metallic alloy for a first time period and then cooling said conically helically shaped coil down from said stress relief temperature for a second time period greater than said first time period.

16. The embolization coil of claim 10 further comprising thrombogenic fibers (26) positioned in said tightly spaced turns at predetermined intervals therealong.

17. The embolization coil of claim 10 further comprising a cannula (28) having a passage extending longitudinally therethrough and in which said conically helically shaped coil is positioned therein.

18. The embolization coil of claim 17 wherein a distal end (29) of said conically helically shaped coil is positioned proximate a distal end (30) of said cannula and wherein a proximal end (31) of said conically helically shaped coil is positioned proximally from said distal end thereof in said cannula.

19. An embolization coil (10) comprising:

a continuous wire strand (11) of a platinum-tungsten alloy (22) that is substantially free of surface oxidation, said strand wound into a longitudinally extending coil (12) having a plurality of tightly spaced turns (13), said longitudinally extending coil wound into a conically helically shaped coil (13) having a plurality of radially expanding turns (16), a distal turn (17) of said radially expanding turns having a minor diameter (18) less than a major diameter (20) of a proximal turn (19) of said radially expanding turns, said major diameter (20) being no greater than 30 mm, said radially expanding turns longitudinally overlapping each other and including proximally increasing spacing (21) from said distal turn to said proximal turn, said conically helically shaped coil of said platinum-tungsten alloy being formed and stress relieved by the steps of;

winding said longitudinally extending coil around a longitudinally tapered mandril (23) with a plurality of minimally spaced turns (24), heating said conically helically shaped coil for a first time period at a stress relief temperature of said platinum-tungsten alloy to relieve stresses formed therein, and then cooling said conically helically shaped coil down from said stress relief temperature over a second time period greater than said first time period to minimize formation of new residual stresses therein; and

thrombogenic fibers (26) positioned in said plurality of tightly spaced turns, selected of said radially expanding turns being positionable within an other thereof, whereby said radially expanding turns longitudinally contact each other in response to blood flowing therethrough to occlude a vessel in which the embolization coil is positioned.