Medical devices using electrosensitive gels
First Claim
1. A drug delivery device comprising an aliquot of a drug;
- a closed, flexible sack surrounding said drug;
a layer of expandable copolymer gel surrounding said flexible sack;
a permeable membrane surrounding said layer of expandable copolymer gel; and
electrode means operably coupled to said expandable copolymer gel to cause controllable contraction of said expandable copolymer gel in response to a voltage applied to said electrode means.
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Accused Products
Abstract
An intelligent material unit formed of an intelligent gel encapsulated within an enclosure. When the gel is actuated by a change in temperature thereof, such as heat and/or by an externally applied field such as an electrical current, electric field, magnetic field, ultrasonic energy (or sonic), microwave energy, a laser beam or a combination thereof, at least a portion of the wall of the container or enclosure is deformed to perform a mechanical function or operation; such as to valve a fluid or cause movement of the container and gel through a fluid or in a passageway. The container may be a thin-skinned flexible plastic, such as an elastomer and may be elongated or sausage-like in shape, or strip-like. It may be free travelling, cantilever-supported or otherwise mounted or attached to a device, machine or element. It may also carry a drug for delivery therefrom at a select location and time.
A system apparatus and method is also disclosed for delivering a quantity of a drug, tissue, cells, genetic material, sensor, implant or implant material, repair material, diagnostic material, protein, hormone or the like or a combination thereof to a select location in the body, such as in an artery, vein, or a portion of the digestive tract. In one form, a select amount of such a (medical) material is disposed within a so-called intelligent gel per se or in one or more small capsules or the like in or attached to such intelligent gel or a container therefor, such as a thin skinned flexible elongated balloon-like enclosure. Such elongated, narrow container or strip of electrical energy or magnetic or radio-frequency energy force responsive gel attached to or containing medical material, is inserted into a body duct such as a vein or artery and is caused to "swim" or wiggle therealong to a select location therein by passing electrical energy through the blood (and vessel wall) and/or by means of an alternating magnetic or radio-frequency field controllably applied thereto with a hand-held instrument which is moved by hand to induce such movement and/or controllably may move such field in a manner to induce the gel to move or swim to the select location. In a particular form, the drug and gel are small enough in size to pass into the bloodstream through the wall of the small intestine after being swallowed, as a drug unit along with other such drug units--when so located at the select location in the body duct, the drug carried by the intelligent gel or (sausage-like) membrane or thin skin contained unit is released therefrom by biodegradation or other means, such as by radio-frequency, ultrasonic or magnetic field energy applied from outside the body or a catheter, or a combination thereof.
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Citations
7 Claims
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1. A drug delivery device comprising an aliquot of a drug;
- a closed, flexible sack surrounding said drug;
a layer of expandable copolymer gel surrounding said flexible sack;
a permeable membrane surrounding said layer of expandable copolymer gel; and
electrode means operably coupled to said expandable copolymer gel to cause controllable contraction of said expandable copolymer gel in response to a voltage applied to said electrode means. - View Dependent Claims (2, 3, 4, 5, 6, 7)
- a closed, flexible sack surrounding said drug;
Specification