Activity-responsive pacer with bipolar sensor electrode

• US 5,800,468 A
• Filed: 02/10/1997
• Issued: 09/01/1998
• Est. Priority Date: 02/12/1996
• Status: Expired due to Term

• Current Assignee: Pacesetter AB
• Original Assignee: Pacesetter AB
• Inventors: Holmstrom, Nils
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US08/797,421
• Time in Patent Office: 568 Days
• Field of Search: 607/17, 607/19, 607/22, 607/26
• US Class Current: 607/17
• CPC Class Codes: A61N 1/056 Transvascular endocardial electrode systems
• CPC Class Codes: A61N 1/36585 controlled by two or more physical parameters
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence

Abstract

A pacemaker system includes an electrode lead having a distal tip electrode for supplying stimulation pulses to cardiac tissue and a ring electrode, the electrode lead being connected to a cardiac stimulator. A detector is contained in a stimulator housing and is connected to the electrode lead for detecting electrical cardiac activity between said ring electrode and said tip electrode. Measurement of a signal dependent on physical activity of the subject in whom the pacemaker is implanted is obtained either by applying a voltage on the ring electrode during a predetermined measuring period and measuring a current through the ring electrode during at least a part of this period, or by, after detection of a QRS wave, applying a potential on the ring electrode and measuring the current between the housing and the ring electrode during the measuring period and also applying an alternating current between the tip electrode and the housing and measuring a voltage difference between the tip electrode and the ring electrode. The stimulation rate is then adjusted dependent on the measured value or values obtained.

Claims

1. A pacemaker system comprising:

an electrode lead having only a distal tip electrode for supplying stimulation pulses to heart tissue and, proximal to said distal tip electrode, a ring electrode;

a cardiac stimulator, which emits stimulation pulses having a stimulation parameter associated therewith, to which said electrode lead is electrically connected;

detector means for detecting electrical cardiac activity between said tip electrode and said ring electrode;

means for applying a measuring parameter on said ring electrode during a predetermined measuring period and for measuring a measurement value through said ring electrode during at least a part of said period for sensing, via said ring electrode, at least one physical activity-dependent parameter;

means for adjusting said stimulation parameter dependent on said measured value.

2. A pacemaker system as claimed in claim 1, wherein said measuring parameter is a potential and said measurement value is a current.

3. A pacemaker system as claimed in claim 1, wherein said measuring parameter is a current and said measurement value is a potential.

4. A pacemaker system as claimed in claim 1, wherein said stimulation pulse parameter comprises a stimulation rate of said stimulation pulses.

5. A pacemaker system as claimed in claim 1, wherein said stimulation pulse parameter comprises an A-V interval.

6. A pacemaker system as claimed in claim 1 wherein said ring electrode is disposed on said electrode lead at a distance from said tip electrode in a range between 6 and 15 cm.

7. A pacemaker system as claimed in claim 1 wherein said ring electrode is disposed on said electrode lead at a distance from said tip electrode in a range between 8 and 15 cm.

8. A pacemaker system as claimed in claim 1 wherein said ring electrode is disposed on said electrode lead at a distance from said tip electrode in a range between 10 and 12 cm.

9. A pacemaker system as claimed in claim 1 wherein said ring electrode is disposed on said electrode lead at a distance from said tip electrode in a range between 5 and 30 mm.

10. A pacemaker system as claimed in claim 1 wherein said ring electrode is disposed on said electrode lead at a distance from said tip electrode in a range between 10-20 and 30 mm.

11. A pacemaker system as claimed in claim 1 wherein said ring electrode comprises means for sensing at least one parameter selected from the group of parameters consisting of blood oxygen pressure, blood flow, impedance, pH value and carbon dioxide pressure.

12. A pacemaker system as claimed in claim 1 wherein said cardiac stimulator has a stimulator housing and a connector housing, said connector housing having a reference electrode on an exterior thereof.

13. A pacemaker system as claimed in claim 1 wherein said means for applying a measuring parameter comprises means for applying a plurality of measuring voltages on said ring electrode during a plurality of consecutive predetermined measuring periods, and means for measuring the current through said ring electrode during each of said measuring periods.

14. A pacemaker system as claimed in claim 1 wherein said cardiac stimulator has a housing having an indifferent electrode on an exterior thereof, and wherein said means for applying a measuring parameter comprises means for applying a DC measuring voltage on said ring electrode during a first measuring period and means for applying an AC current between said housing and said tip electrode during a second measuring period, said first and second measuring periods being consecutive, and means for measuring the current through said ring electrode during said first measuring period and means for measuring a voltage between said tip electrode and said ring electrode during said second measuring period.

15. A system for controlling a stimulation frequency of a cardiac pacemaker dependent on physical activity, said pacemaker adapted for implantation in a human body and having a cardiac stimulator in said housing which emits stimulation pulses at said rate, and a connector housing having a reference electrode on an exterior thereof, said system comprising:

a bipolar lead having a distal tip electrode adapted for implantation in a ventricle and a ring electrode disposed a distance from said tip electrode in a range from 6-15 cm;

means in said housing for detecting a potential difference between said tip electrode and said ring electrode;

means in said housing for applying, after detection of a QRS wave by said means for detecting, a physiological parameter measuring potential on said ring electrode, relative to said reference electrode, for a predetermined measuring time;

means in said housing for measuring a current between said housing and said ring electrode during at least a portion of said measuring time; and

means for triggering said cardiac stimulator to emit pacing pulses between said pacemaker housing and said tip electrode at a rate dependent on said current.

16. A system as claimed in claim 15 wherein said pacemaker housing has an indifferent electrode formed by an external layer of carbon, and wherein said means for measuring the current between said housing and said ring electrode comprises means for measuring the current between the carbon layer and said ring electrode.

17. A system for controlling a stimulation frequency of a cardiac pacemaker dependent on physical activity, said pacemaker adapted for implantation in a human body and having a cardiac stimulator in said housing which emits stimulation pulses at said rate, and a connector housing having a reference electrode on an exterior thereof, said system comprising:

a bipolar lead having a distal tip electrode adapted for implantation in a ventricle, and a ring electrode proximal to said tip electrode;

means in said housing for detecting a potential difference between said tip electrode and said ring electrode;

means for applying, after detection of a QRS wave by said means for detecting, a physiological parameter measuring potential on said ring electrode, relative to said reference electrode, for a predetermined measuring time;

means for measuring a current between said housing and said ring electrode during at least a portion of said measuring time;

means for supplying an alternating current between said tip electrode and said housing;

means for measuring a voltage difference between said tip electrode and said ring electrode; and

means for triggering emission of stimulation pulses by said cardiac stimulator between said housing and said tip electrode at a rate dependent on both the current measured between said housing and said ring electrode and the voltage difference measured between said tip electrode and said ring electrode.

18. A system as claimed in claim 17 wherein said pacemaker housing has an indifferent electrode formed by an external layer of carbon, and wherein said means for measuring a current comprises means for measuring a current between said carbon layer and said ring electrode.

19. A system as claimed in claim 17 wherein said ring electrode is disposed on said electrode lead at a distance from said tip electrode in a range between 5 and 30 mm.

20. A system as claimed in claim 17 wherein said ring electrode is disposed on said electrode lead at a distance from said tip electrode in a range between 6 and 15 cm.

21. A system as claimed in claim 17 wherein said ring electrode is disposed on said electrode lead at a distance from said tip electrode in a range between 8 and 15 cm.