Wireless prosthetic electrode for the brain

• US 5,800,535 A
• Filed: 11/01/1994
• Issued: 09/01/1998
• Est. Priority Date: 02/09/1994
• Status: Expired due to Term

• Current Assignee: Iowa State University Research Foundation Incorporated (Iowa State University)
• Original Assignee: University of Iowa Research Foundation
• Inventors: Howard, Matthew A. III
• Primary Examiner(s): Clarke, Robert A.
• Application Number:
  US08/332,757
• Time in Patent Office: 1,400 Days
• Field of Search: 600/25, 607/2, 607/55-57, 623/10-11, 623/24, 623/66
• US Class Current: 623/10
• CPC Class Codes: A61F 11/00 Methods or devices for treatment of the ears or hearing sense implantable prostheses that substitute or replace internal ear parts, e.g. ear-drums, A61F2/18; methods or devices to cause a change in the state of auditory consciousness A61M21/00; electrotherapy applying electrical stimulation of the auditory system, or circuits therefor A61N1/36; radiotherapy using optical stimulation of the auditory system A61N5/06; electro-acoustic hearing aids H04R25/00; Non-electric hearing aids; Methods or devices for enabling ear patients to achieve auditory perception through physiological senses other than hearing sense; Protective devices for the ears, carried on the body or in the hand headwear, e.g. caps or helmets, with means for protecting the ears A42B1/0188, A42B3/16
• CPC Class Codes: A61F 11/04 Methods or devices for enabling ear patients to achieve auditory perception through physiological senses other than hearing sense, e.g. through the touch sense electronic stimulation of auditory nerves A61N1/36036
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/0529 Electrodes for brain stimulation
• CPC Class Codes: A61N 1/0531 Brain cortex electrodes
• CPC Class Codes: A61N 1/0539 Anchoring of brain electrode systems, e.g. within burr hole
• CPC Class Codes: A61N 1/0541 Cochlear electrodes

Abstract

A wireless neural prosthetic device for a primary auditory cortex of a patient includes either a speech processor or a stimulating device for receiving and processing information and a wireless electrode arranged in the primary auditory cortex having a plurality of electrical contacts. The electrode can be arranged in the patient'"'"'s primary auditory cortex and each of the plurality of electrical contacts independently outputs electrical discharges in accordance with the processed electrical signals. The plurality of electrical contacts can be arranged to approximately tonotopically match the primary auditory cortex.

Claims

1. A wireless neural prosthetic device for placement in a brain target zone of a patient, for receiving processed electrical signals from an exterior processing device, said prosthetic device comprising:

a thin, elongated electrode support adapted for tonotopic arrangement in said brain target zone having a plurality of electrical contacts arranged to electrically couple with said brain target zone; and

circuitry electrically coupled to said plurality of electrical contacts for receiving said processed electrical signals and for selectively outputting electrical discharges to said plurality of electrical contacts in accordance with said processed electrical signals.

2. The wireless neural prosthetic device as claimed in claim 1, wherein said plurality of electrical contacts comprise a plurality of metal pads arranged on said electrode support as a three-dimensional array, and wherein said plurality of electrical contacts are adapted for geometric arrangement within said brain target zone.

3. The wireless neural prosthetic device as claimed in claim 1, wherein said electrode support is substantially cylindrical, and wherein said plurality of contacts are electrically coupled to said circuitry by a respective plurality of conductive media.

4. The wireless neural prosthetic device as claimed in claim 1, wherein said plurality of electrical contacts are spaced less than about 2 millimeters apart, and said circuitry is at least partially contained within said electrode support.

5. The wireless neural prosthetic device as claimed in claim 1, wherein said electrode support has an attachment end and a penetrating end, wherein said penetrating end is adapted to penetrate brain tissue to arrive at said brain target zone, and wherein said circuitry is arranged approximately at said attachment end.

6. The wireless neural prosthetic device as claimed in claim 1, further comprising a brain anchor attached to said electrode support for allowing said electrode support to remain within said brain target zone despite brain pulsing.

7. The wireless neural prosthetic device as claimed in claim 6, wherein said brain anchor comprises an inflatable brain anchor.

8. The wireless neural prosthetic device as claimed in claim 6, wherein said brain anchor comprises at least one of rubber and plastic.

9. The apparatus as claimed in claim 1, wherein said circuitry comprises a receiving antenna for receiving said processed electrical signals.

10. The apparatus as claimed in claim 1, further comprising a transmitting antenna coupled to said circuitry, wherein said circuitry receives neural activity signals from said plurality of electrical contacts and transforms said neural activity signals into electromagnetic waves with said neural activity signals modulated thereon and said transmitting antenna transmits said electromagnetic waves.

11. A wireless neural prosthetic system for a targeted brain zone of a patient, comprising:

a processor for outputting processed electrical signals;

a thin, elongate electrode support adapted for tonotopic arrangement in said targeted brain zone and having a plurality of electrical contacts capable of outputting electrical discharges in accordance with said processed electrical signals; and

circuitry, electrically coupled to said plurality of electrical contacts, for receiving said processed electrical signals and outputting electrical discharges to said plurality of electrical contacts in accordance with said processed electrical signals.

12. The apparatus as claimed in claim 11, further comprising a transmitting antenna coupled to said circuitry, wherein said circuitry receives neural activity signals from said plurality of electrical contacts and transforms said neural activity signals into electromagnetic waves with said neural activity signals modulated thereon and said transmitting antenna transmits said electromagnetic waves.

13. The apparatus as claimed in claim 12, further comprising a processor antenna coupled to said processor for receiving and transmitting said electromagnetic waves to said processor.

14. The apparatus as claimed in claim 13, wherein said processor demodulates said electromagnetic waves, thereby yielding signals corresponding to said neural activity.

15. A neural prosthetic apparatus for an auditory cortex of a patient, comprising:

a speech processor for receiving and processing audio information and for outputting processed electrical signals;

a thin, elongated electrode support adapted for tonotopic arrangement in said auditory cortex and having a plurality of electrical contacts arranged on said electrode support, wherein each of said plurality of electrical contacts is adapted to output electrical discharges in accordance with said processed electrical signals; and

circuitry electrically coupled to said plurality of electrical contacts for receiving said processed electrical signals and outputting electrical discharges to said plurality of electrical contacts in accordance with said processed electrical signals.

16. The neural prosthetic apparatus as claimed in claim 15, wherein said electrode support is adapted for stereotactic placement in said auditory cortex of the patient, and said plurality of electrical contacts are arranged on said electrode support such that each of said plurality of electrical contacts is capable of stimulating a geometrically separate location of said auditory cortex.

17. The neural prosthetic apparatus as claimed in claim 16, further comprising:

at least one additional electrode support adapted for tonotopic arrangement in said auditory cortex, said at least one additional electrode support having an additional plurality of electrical contacts, said additional plurality of electrical contacts being capable of outputting additional electrical discharges in accordance with said electrical signals.

18. The neural prosthetic apparatus as claimed in claim 15, wherein said plurality of electrical contacts are approximately uniformly arranged along said electrode support.

19. The neural prosthetic apparatus as claimed in claim 15, wherein said electrical contacts are spaced approximately 50 to 150 micrometers apart.

20. A neural prosthetic apparatus for an auditory cortex of a patient, comprising:

a speech processor for receiving and processing audio information and for outputting processed electrical signals;

a thin, elongated electrode support adapted for tonotopic arrangement within said auditory cortex and having a plurality of electrical contacts approximately uniformly arranged along said electrode support, each of said plurality of electrical contacts being capable of independently outputting electrical discharges in accordance with said processed electrical signals; and

circuitry electrically coupled to said plurality of electrical contacts for receiving said processed electrical signals and outputting electrical discharges to said plurality of electrical contacts in accordance with said processed electrical signals.

21. A neural prosthetic apparatus for a patient with tinnitus, comprising:

a stimulation device for outputting electrical signals; and

a thin elongated electrode support, adapted for arrangement in the patient'"'"'s cortex or thalamus, said electrode support having a plurality of electrical contacts electrically coupled to said stimulation device, said plurality of electrical contacts capable of selectively outputting electrical discharges in accordance with said electrical signals.

22. The neural prosthetic apparatus as claimed in claim 21, further comprising:

at least one additional electrode support having an additional plurality of electrical contacts electrically coupled to said stimulation device, said at least one additional electrode support being adapted for tonotopic arrangement in the patient'"'"'s cortex or thalamus, said additional plurality of electrical contacts being capable of outputting additional electrical discharges in accordance with said electrical signals.