Breathing gas delivery method and apparatus

• US 5,803,065 A
• Filed: 01/18/1996
• Issued: 09/08/1998
• Est. Priority Date: 09/22/1989
• Status: Expired due to Term

• Current Assignee: RIC INVESTMENTS LLC (Koninklijke Philips N.V.)
• Original Assignee: Respironics Incorporated (Koninklijke Philips N.V.)
• Inventors: Estes, Mark, Zdrojkowski, Ronald J.
• Primary Examiner(s): Yu, Mickey
• Assistant Examiner(s): SRIVASTAVA, VIRENDRA KUMAR
• Application Number:
  US08/588,598
• Time in Patent Office: 964 Days
• Field of Search: 128/202.22, 128/204.18, 128/204.21, 128/204.23, 128/204.26, 128/848, 128/205.25, 128/207.18, 73/40.5
• US Class Current: 128/204.23
• CPC Class Codes: A61M 16/0066 Blowers or centrifugal pumps
• CPC Class Codes: A61M 16/0069 the speed thereof being controlled by respiratory parameters, e.g. by inhalation
• CPC Class Codes: A61M 16/026 specially adapted for predicting, e.g. for determining an information representative of a flow limitation during a ventilation cycle by using a root square technique or a regression analysis
• CPC Class Codes: A61M 16/06 Respiratory or anaesthetic masks
• CPC Class Codes: A61M 16/204 used for inhalation control
• CPC Class Codes: A61M 16/205 used for exhalation control
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0036 in the breathing tube and used in both inspiratory and expiratory phase
• CPC Class Codes: A61M 2205/15 Detection of leaks
• CPC Class Codes: A61M 2205/3561 local, e.g. within room or hospital

Abstract

An improved methodology and systems for delivery of breathing gas such as for the treatment of obstructive sleep apnea through application of alternating high and low level positive airway pressure within the airway of the patient with the high and low airway pressure being coordinated with the spontaneous respiration of the patient, and improved methods and apparatus for triggering and for leak management in such systems.

Claims

1. A method of determining a leak component of gas flow in a respiratory gas supply system for supplying respiratory gas to a patient, comprising the steps of:

determining a beginning and an end of a plurality of patient breaths, each breath comprised of an inspiratory phase and an expiratory phase;

integrating patient respiratory gas flow rate throughout said plurality of patient breaths to determine a total respiratory gas volume for said plurality of patient breaths; and

dividing said total respiratory gas volume for said plurality of patient breaths by a time duration of said plurality of patient breaths to determine a leakage rate for said plurality of patient breaths.

2. The method as set forth in claim 1 including the additional step of averaging said leakage rates of said plurality of patient breaths to determine an average rate of respiratory gas leakage from such a respiratory gas supply system.

3. The method as set forth claim 1 wherein said determining the beginning and end of said plurality of patient breath includes the additional steps of continually monitoring the total flow rate of gas supplied by such a respiratory gas supply system, and first continually comparing said total flow rate of gas with a parameter corresponding to said leakage rate to detect a first condition characterized by said total flow rate being greater than said leakage rate.

4. The method as set forth in claim 3 wherein said determining the beginning and end of said plurality of patient breaths includes the additional steps of second continually comparing said total flow rate of gas with said parameter corresponding to said leakage rate to detect a second condition characterized by said total flow rate being less than said leakage rate, and identifying the occurrence of said exhalation phases by a third condition characterized by occurrence of said second condition continuously for a predetermined period of time.

5. The method as set forth in claim 4 including the additional steps of periodically repeating said determining, integrating and dividing steps to obtain updated values of said leakage rate, and utilizing said updated values to repetitively perform said continually monitoring, said first and second continually comparing, and said identifying steps.

6. A method of determining the rate of leakage from a respiratory gas supply system which supplies respiratory gas flow to a patient at specified flow rates and pressures comprising the steps of:

determining said rate of leakage as a leak which is proportional to the square root of pressure by a constant of proportionality K, where ##EQU3## the numerator of eq. 1 representing average leak flow and the denominator of eq. 1 representing the relationship between the leak rate and pressure.

7. A method of determining gas leakage in a respiratory gas supply system for supplying respiratory gas to a patient comprising the steps of:

determining the time duration of at least one patient breath;

determining the average leak rate for said at least one patient breath;

multiplying said average leak rate by said time duration of said at least one breath to determine a total leakage flow for said at least one breath;

determining the average of a given function of gas pressure for said at least one breath;

dividing said total leakage of said at least one breath by said average of said given function of gas pressure for said at least one breath to determine a constant of proportionality relating said average pressure to said leak rate;

periodically determining the instantaneous pressure occurring during another patient breath subsequent to said at least one breath; and

multiplying said given function of said periodically determined instantaneous pressures by said constant of proportionality to determine a leakage rate for said another patient breath as a function of pressure during said another patient breath.

8. A method of determining the rate of leakage from a respiratory gas supply system which supplies respiratory gas flow to a patient at specified flow rates and pressures comprising the steps of:

determining said rate of leakage as a leak which is proportional to a given function of pressure by a constant of proportionality K, where ##EQU4## the numerator of eq. 2 representing average leak flow and the denominator of eq. 2 representing the relationship between the leakage and pressure.