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Electrode assembly for assaying glucose

  • US 5,804,048 A
  • Filed: 08/15/1996
  • Issued: 09/08/1998
  • Est. Priority Date: 08/15/1996
  • Status: Expired due to Term
First Claim
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1. An electrode assembly for use in assaying glucose in a solution, the electrode assembly comprising:

  • a sensor electrode; and

    a membrane assembly overlaying the sensor electrode the membrane assembly includingan outer, diffusion-barrier layer positioned to contact the solution, the outer layer having a substantially uniform thickness and having a distribution of pores of a specific density and of a size in the range of 0.0125 to 0.0200 microns.an inner, interference-barrier layer contacting a face of the sensor electrode and having a substantially uniform thickness, wherein the inner layer includes a relatively thick, porous backing film and a relatively thin, porous overlaying film that overlays the backing film, andan immobilized glucose oxidase layer interposed between the outer and inner layers and having a substantially uniform thickness,wherein the outer layer is configured to allow glucose and oxygen to diffuse through it to reach the glucose oxidase layer, where the glucose and oxygen react to form reaction products that include hydrogen peroxide,and wherein the inner layer is configured to have a permeability sufficient to pass hydrogen peroxide from the glucose oxidase layer to the face of the sensor electrode.

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