Synthetic receptors, libraries and uses thereof
First Claim
1. A synthetic receptor which comprises a polyfunctional organic template covalently linked to two or more oligomer which may independently be straight chained or branched oligoamide, oligoester, oligourea, oligourethane, oligoamine, oligoether, oligosulfonamide, oligophosphonamide, oligophoephonate, oligophqsphate, oligonucleotide, oligosaccharide, peptide oligomer, or a mixture of monomers thereof;
- wherein each oligomer independently contains 2 to 10 monomers; and
wherein the polyfunctional organic template is a polycarbocyclic.
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Abstract
The invention is directed to synthetic receptor(s) which comprises a polyfunctional organic template covalently linked to two or more oligomers which may independently be the same or different and may independently be straight chain or branched. The template may be linked to an identifier which uniquely defines the synthetic receptor. The identifier is a stable chemical molecule or a plurality of stable chemical molecules distinguishable and detectable to picomolar levels or may be an oligonucleotide. In an preferred embodiment, the template is covalently linked to a solid support which is linked to an identifier.
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Citations
14 Claims
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1. A synthetic receptor which comprises a polyfunctional organic template covalently linked to two or more oligomer which may independently be straight chained or branched oligoamide, oligoester, oligourea, oligourethane, oligoamine, oligoether, oligosulfonamide, oligophosphonamide, oligophoephonate, oligophqsphate, oligonucleotide, oligosaccharide, peptide oligomer, or a mixture of monomers thereof;
- wherein each oligomer independently contains 2 to 10 monomers; and
wherein the polyfunctional organic template is a polycarbocyclic. - View Dependent Claims (2, 3, 4, 8, 9, 10, 11, 12)
- wherein each oligomer independently contains 2 to 10 monomers; and
- 5. A synthetic receptor which comprises a polyfunctional steroid template covalently linked to two or more peptide oligomers which may independently be the same or different and which may independently be straight chain or branched.
Specification