Pump for use in non-invasive or minimally invasive detection of analytes

• US 5,807,274 A
• Filed: 07/11/1997
• Issued: 09/15/1998
• Est. Priority Date: 12/18/1995
• Status: Expired due to Fees

• Current Assignee: Abbott Laboratories
• Original Assignee: Abbott Laboratories
• Inventors: Warnke, Kevin C., Elstrom, Tuan A., Henning, Timothy P., Shain, Eric B.
• Primary Examiner(s): Hindenburg, Max
• Assistant Examiner(s): WINGOOD, PAMELA LYNN
• Application Number:
  US08/890,762
• Time in Patent Office: 431 Days
• Field of Search: 604/313, 604/316, 600/562, 600/565, 600/573
• US Class Current: 600/565
• CPC Class Codes: A61B 5/14514 using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150221 Valves
• CPC Class Codes: A61B 5/150229 Pumps for assisting the blood sampling
• CPC Class Codes: A61B 5/15134 Bladeless capillary blood sampling devices, i.e. devices for perforating the skin in order to obtain a blood sample but not using a blade, needle, canula, or lancet, e.g. by laser perforation, suction or pressurized fluids
• CPC Class Codes: A61B 5/157 Devices characterised by integrated means for measuring characteristics of blood
• CPC Class Codes: A61B 5/441 Skin evaluation, e.g. for skin disorder diagnosis

Abstract

This disclosure relates to a device and method for the non-invasive or minimally invasive withdrawal of fluids from a patient by the use of a self-actuated pump connected to a analyte sensing unit. The self-actuated pump is preferably mounted in the patient'"'"'s shoe.

Claims

1. A device for extracting and monitoring a bodily fluid of a patient, comprising:

(a) a self-actuated pump located adjacent a moving body part of said patient, said pump capable of producing a negative pressure by mechanical forces generated by said moving body part to extract said bodily fluid;

(b) a sensing unit located adjacent to said patient'"'"'s body, and

(c) pneumatic conduit connecting the self-actuated pump to the sensing unit,

wherein the self-actuated pump is operated by walking.

2. A device for extracting and monitoring a bodily fluid of a patient, comprising:

(a) a self-actuated pump located adjacent a moving body part of said patient, said pump capable of producing a negative pressure by mechanical forces generated by said moving body part to extract said bodily fluid,

(b) a sensing unit located adjacent to said patient'"'"'s body, and

(c) a pneumatic conduit connecting the self-actuated pump to the sensing unit,

wherein the self-actuated pump is operated by motion caused by breathing of the patient.

3. A method of extracting and monitoring an analyte in a bodily fluid of a patient comprising the steps of:

(a) providing an extraction and monitoring device comprising

(i) a self-actuated pump located adjacent a moving body part of said patient, said pump capable of producing a negative pressure by mechanical forces generated by said moving body part to extract said bodily fluid, wherein said mechanical forces are generated by an up and down motion of said body part or by a motion caused by breathing of the patient,

(ii) a sensing unit located adjacent to said patient'"'"'s body, and

(iii) a pneumatic conduit connecting the self-actuated pump to the sensing unit;

(b) activating the self-actuated pump and extracting the bodily fluid such that the fluid is in contact with the sensing unit; and

(c) detecting presence or amount of the analyte in the bodily fluid with the sensing unit.

4. The method according to claim 3 further providing a visual readout of the presence or amount of the analyte in the body fluid.