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Non-invasive carboxyhemoglobin analyer

  • US 5,810,723 A
  • Filed: 12/05/1996
  • Issued: 09/22/1998
  • Est. Priority Date: 12/05/1996
  • Status: Expired due to Fees
First Claim
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1. A non-invasive method for measuring the concentration of carboxyhemoglobin in a subject'"'"'s blood, said method comprising the steps of:

  • (a) converting the reduced hemoglobin constituent of said subject'"'"'s blood to oxyhemoglobin by providing supplemental oxygen;

    (b) directing light of two different wavelengths through a tissue of the subject in which pulsatile flow of blood through an arterial blood vessel can be detected, the first of said wavelengths being absorbed substantially equally by the oxy- and carboxyhemoglobin constituents of the subject'"'"'s blood, and the second of said wavelengths being absorbed differentially by the oxy- and carboxyhemoglobin constituents of the subject'"'"'s blood;

    (c) detecting the portion of said light of the two different wavelengths that has passed through the arterial blood vessel of said subject;

    (d) determining the pulsatile changes in absorbance of the two wavelengths of light by the subject'"'"'s arterial blood;

    (e) determining the ratio of change in absorbance of the two wavelengths, and;

    (f) calculating the concentration of carboxyhemoalobin in said subject'"'"'s blood by comparing the ratio of change in absorbance of the two wavelengths to ratios measured in subjects with known carboxyhemoglobin levels.

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