×

Methods of increasing nitric oxide synthesis

  • US 5,811,437 A
  • Filed: 04/22/1997
  • Issued: 09/22/1998
  • Est. Priority Date: 05/21/1996
  • Status: Expired due to Fees
First Claim
Patent Images

1. A method for increasing nitric oxide (NO) synthesis in vascular endothelial cells in a human in need thereof, comprising administering to said human a compound of formula I ##STR3## Wherein:

  • R is hydrogen, --OH, --O(C1 -C4 alkyl), --OCO(C1 -C4 alkyl), or --OCOAr where Ar is a phenyl or optionally substituted phenyl;

    R1 is R, --Cl, or --F;

    R2 is 1-pyrrolidinyl, 1-piperidinyl, or 1-hexamethyleneimino;

    or a pharmaceutically acceptable salt or solvate thereof.

View all claims
  • 1 Assignment
Timeline View
Assignment View
    ×
    ×