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Vitamin-D amide derivatives

  • US 5,811,562 A
  • Filed: 11/20/1996
  • Issued: 09/22/1998
  • Est. Priority Date: 03/23/1994
  • Status: Expired due to Fees
First Claim
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1. Compounds of general formula (I) ##STR13## where R1 and R2, which may be the same or different, each represent a hydrogen atom or an aliphatic, cycloaliphatic, araliphatic or aryl group or together with the nitrogen atom to which they are attached form a heterocyclic group;

  • R3 represents a methyl group having α

    - or β

    -configuration;

    one of Ra and Rb represents a hydroxy group or protected hydroxy group and the other represents a hydrogen atom;

    Y represents a valence bond or an alkylene group containing up to 3 carbon atoms; and

    A= represents a cyclohexylidene moiety characteristic of the A-ring of a 1α

    -hydroxylated vitamin D or analogue thereof.

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