Arrangement for noninvasive determination of the oxygen saturation in human blood vessels or organs

• US 5,817,009 A
• Filed: 05/06/1996
• Issued: 10/06/1998
• Est. Priority Date: 11/28/1994
• Status: Expired due to Fees

• Current Assignee: MIPM Mammendorfer Institut fuer Physik und Medizin GmbH
• Original Assignee: MIPM Mammendorfer Institut fuer Physik und Medizin GmbH
• Inventors: Rosenheimer, Michael N., Gruenwald, Sandra
• Primary Examiner(s): Bahr, Jennifer
• Assistant Examiner(s): WINAKUR, ERIC FRANK
• Application Number:
  US08/643,630
• Time in Patent Office: 883 Days
• Field of Search: 600/323, 600/326, 600/327, 600/339, 600/340, 600/341, 600/338
• US Class Current: 600/339
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/7207 of noise induced by motion artifacts

Abstract

Arrangement for determining the oxygen saturation in human blood vessels and organs with a measurement sensor with at least two light sources of different wavelengths--preferably wavelengths of 660 nm and 940 nm--and with at least one receiver which receives the light transmitted and reflected from the oxygen particles which are bonded with the hemoglobin in the irradiated vessel or organ and transmits it as an electrical signal to a pulsoximeter for evaluation of the measurement results and readout on a display device. An additional measurement sensor is associated with the measurement sensor for locating a blood vessel or organ to be selected and the two measurement sensors are designed such that they can be handled together as a constructional unit.

Claims

1. A method for the non-invasive in vivo determination of oxygen saturation in human blood vessels and organs comprising:

a) providing a first oxygen measurement sensor having at least two light sources of different wavelengths and at least one receiver therefor;

b) providing a second position measurement sensor which forms a constructional unit with the first oxygen measurement sensor;

c) locating a specific position external to but adjacent to a predetermined vessel or organ with the second position measurement sensor;

d) positioning the first oxygen measurement sensor at the specific position and monitoring the position with the second position measurement sensor;

e) radiating light from the light sources on the blood vessel or organ, such that the light which is transmitted by oxygen particles bonded with hemoglobin in the irradiated blood vessel or organ and reflected by the surrounding tissue is received by the receiver;

f) converting the reflective light received by the receiver into an electrical signal that is proportional to the intensity of the reflected light;

g) transmitting the electrical signal to a pulsoximeter to determine the oxygen saturation in the blood vessel or organ.

2. The method of claim 1 wherein the first oxygen measurement sensor generates two beams, each of which is symmetrical at an angle to a vertical axis, these beams intersecting at an intersection point on the vertical axis, and at least one shared receiver is associated with these beams.

3. The method of claim 1 wherein the second position measurement sensor is a sonography transmitter-receiver and wherein said sensor emits ultrasonic waves, said ultrasonic waves and the light radiated from the light sources being emitted in substantially the same direction.

4. A device for carrying out the method of claim 1 comprising a first oxygen measurement sensor having at least two light sources and one receiver, a second position measurement sensor for locating a blood vessel or organ, said second position measurement sensor forming a jointly manipulable constructional unit with the first oxygen measurement sensor, said receiver being connected to a pulsoximeter and said pulsoximeter being connected to a display device.

5. The device according to claim 4, wherein the constructional unit is part of a catheter.

6. The device according to claim 4, wherein the second position measurement sensor is a pressure sensor.

7. The device according to claim 4, wherein the first oxygen measurement sensor has a receiver and two light-generating and light-transmitting systems, whose beam paths are arranged at an angle symmetrically to the vertical axis.

8. The device according to claim 4, wherein each light-generating and light-conducting system can be adjusted by adjusting means and fixed by clamping means at an angle, wherein one system generates and conducts red light and the other system generates and conducts infrared light, a system comprising, in each instance, within a tube, an objective lens, collimating objective lenses and light sources, wherein each tube has an ankle joint in the region of the objective lens, wherein the receivers are arranged parallel to the vertical axis in a receiver housing which has the ankle joints and which is arranged symmetrically with respect to the vertical axis, wherein each system is connected with the ankle joint of the tube and is supported in the ankle joints of the receiver housing so as to be swivelable relative to the vertical axis, and wherein a cover for screening out extraneous light is associated with the light-generating and light-conducting systems and with the receivers.

9. The device of claim 4 wherein the first oxygen measurement sensor and the second position measurement sensor are detachably connected to one another.

10. The device according to claim 9, wherein the measurement sensor and the first oxygen measurement sensor form a constructional unit which can be placed on a catheter.

11. The device according to claim 9, wherein the second position measurement sensor and the first oxygen measurement sensor form a unit which is integrated in the distal end of the catheter.

12. The device according to claim 9, wherein means for aligning the beam axes of the first oxygen measurement sensor and/or the beam axes of the additional measurement sensor are arranged in the catheter.

13. A method for the non-invasive in vivo determination of oxygen saturation in human blood vessels and organs comprising:

a) providing a first oxygen measurement sensor having at least two light sources of different wavelengths and at least one receiver therefor;

b) providing a second position measurement sensor comprising a sonography transmitter-receiver which emits ultrasonic waves, which forms a constructional unit with the first oxygen measurement sensor;

c) locating a specific position external to but adjacent to a predetermined vessel or organ with the second position measurement sensor;

d) positioning the first oxygen measurement sensor at the specific position and monitoring the position with the second position measurement sensor;

e) radiating light from the light sources on the blood vessel or organ, such that the light which is transmitted by oxygen particles bonded with hemoglobin in the irradiated blood vessel or organ and reflected by the surrounding tissue is received by the receiver;

f) converting the reflective light received by the receiver into an electrical signal that is proportional to the intensity of the reflected light;

g) transmitting the electrical signal to a pulsoximeter to determine the oxygen saturation in the blood vessel or organ.