Collimator-free photon tomography
First Claim
1. A method of photon computed tomography comprising:
- administering a radioisotope to a patient (14) for producing gamma ray photons (16) from a source (14a) inside said patient;
measuring emissivity of said photons (16) externally of said patient (14) at a plurality of measurement positions (24) surrounding said patient (14) for obtaining corresponding energy spectrums (E);
predicting photon emissivity (Q) at said plurality of measurement positions (24) using an initial prediction of an image (I) of said source (14a);
comparing said predicted and measured photon emissivities (Q,M) to obtain differences (d) therebetween; and
iterating said predicting and comparing steps by updating said image prediction (I) until said differences (d) are below a threshold for obtaining a final prediction of said image (In).
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Abstract
A method of uncollimated single photon emission computed tomography includes administering a radioisotope to a patient for producing gamma ray photons from a source inside the patient. Emissivity of the photons is measured externally of the patient with an uncollimated gamma camera at a plurality of measurement positions surrounding the patient for obtaining corresponding energy spectrums thereat. Photon emissivity at the plurality of measurement positions is predicted using an initial prediction of an image of the source. The predicted and measured photon emissivities are compared to obtain differences therebetween. Prediction and comparison is iterated by updating the image prediction until the differences are below a threshold for obtaining a final prediction of the source image.
43 Citations
19 Claims
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1. A method of photon computed tomography comprising:
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administering a radioisotope to a patient (14) for producing gamma ray photons (16) from a source (14a) inside said patient; measuring emissivity of said photons (16) externally of said patient (14) at a plurality of measurement positions (24) surrounding said patient (14) for obtaining corresponding energy spectrums (E); predicting photon emissivity (Q) at said plurality of measurement positions (24) using an initial prediction of an image (I) of said source (14a); comparing said predicted and measured photon emissivities (Q,M) to obtain differences (d) therebetween; and iterating said predicting and comparing steps by updating said image prediction (I) until said differences (d) are below a threshold for obtaining a final prediction of said image (In). - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A photon computed tomography system (10) for imaging a source (14a) in a patient (14) producing gamma ray photons (16) comprising:
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means (12) for measuring emissivity of said photons (16) externally of said patient (14) at a plurality of measurement positions (24) surrounding said patient (14) for obtaining corresponding energy spectrums (E); means (20b) for predicting photon emissivity (Q) at said plurality of measurement positions (24) using an initial prediction of an image (I) of said source (14a); means (20b) for comparing said predicted and measured photon emissivities (Q,M) to obtain differences (d) therebetween; and means (20b) for iterating said predicting and comparing steps by updating said image prediction (I) until said differences (d) are below a threshold for obtaining a final prediction of said image (In). - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19)
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Specification