Interstitial fluid collection and constituent measurement
First Claim
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1. A method for testing a sample of body fluid, said method comprising:
- forming an artificial opening through a patient'"'"'s skin with said opening extending into but not through a dermal layer of said skin with said opening sized to access a constituent-containing, substantially blood-free fluid in said dermal layer without penetrating blood laden capillaries;
drawing a sample of said blood-free fluid through said opening; and
testing said sample for said constituent.
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Abstract
An apparatus and method is disclosed for obtaining and measuring constituents in a sample of body fluid. The apparatus includes a member which is sized to penetrate into at least the dermal layer of skin to collect a sample of body fluid located within the dermal layer.
589 Citations
16 Claims
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1. A method for testing a sample of body fluid, said method comprising:
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forming an artificial opening through a patient'"'"'s skin with said opening extending into but not through a dermal layer of said skin with said opening sized to access a constituent-containing, substantially blood-free fluid in said dermal layer without penetrating blood laden capillaries; drawing a sample of said blood-free fluid through said opening; and testing said sample for said constituent. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A method for testing a sample of body fluid, said method comprising:
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inserting a penetration member into a patient'"'"'s skin with said penetration member extending into but not through a dermal layer of said skin with said penetration member sized to access a constituent-containing, substantially blood-free fluid in said dermal layer without penetrating blood laden capillaries; and testing said accessed fluid for said constituent. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16)
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Specification