Medical noninvasive operations using focused modulated high power ultrasound
First Claim
1. Noninvasive surgical apparatus for affecting a medical target in a living being by destruction of undesired tissue or coagulation of blood, said apparatus comprising:
- low frequency ultrasound means, including a low frequency ultrasound signal, for controlling growth of cavitation microbubbles in a medical target region, said low frequency ultrasound signal having an amplitude below a cavitation threshold of the target region,means for superimposing at least one high frequency ultrasound signal onto the low frequency signal in order to produce a modulated ultrasound signal having an amplitude that exceeds said cavitation threshold, said modulated signal having a focal zone of a size determined by the high frequency signal; and
means for positioning the focal zone of the modulated signal into the medical target region in order to cause vaporous cavitation therein.
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Abstract
Medical noninvasive operations using focused modulated high power ultrasound in accordance with the present invention generally includes a transmitter for exciting a multifrequency ultrasound wave for causing vaporous cavitation bubbles in a small focal zone of a medical target region. Focused ultrasound can be used for both dissolving tissues as well as causing clots in order to destroy cancerous growths. The multifrequency wave includes an underlying low frequency signal for enabling optimal growth of microbubbles and at least one high frequency signal for enabling a narrow zone of focus of the ultrasound. A cavitation monitor may be provided for sensing a level of cavitation as well as providing feedback to the transmitter. In addition, an imaging system is provided for enabling viewing of the medical target area during the therapy.
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Citations
20 Claims
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1. Noninvasive surgical apparatus for affecting a medical target in a living being by destruction of undesired tissue or coagulation of blood, said apparatus comprising:
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low frequency ultrasound means, including a low frequency ultrasound signal, for controlling growth of cavitation microbubbles in a medical target region, said low frequency ultrasound signal having an amplitude below a cavitation threshold of the target region, means for superimposing at least one high frequency ultrasound signal onto the low frequency signal in order to produce a modulated ultrasound signal having an amplitude that exceeds said cavitation threshold, said modulated signal having a focal zone of a size determined by the high frequency signal; and means for positioning the focal zone of the modulated signal into the medical target region in order to cause vaporous cavitation therein. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. Noninvasive surgical apparatus comprising an ultrasound transmitter, including:
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a source of a high frequency ultrasound signal, a source of a low frequency ultrasound signal, said low frequency ultrasound signal having an amplitude below a cavitation threshold of a medical target region in order to enhance bubble growth during vaporous cavitation and means for superimposing the high frequency signal and the low frequency signal in order to produce a modulated, multifrequency signal; and means for focusing the multifrequency signal into the medical target region in order to produce vaporous cavitation therein. - View Dependent Claims (10, 11, 12, 13, 14, 15)
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16. A method for performing noninvasive surgery using modulated high powered ultrasound, said method comprising the steps of:
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inducing a low frequency ultrasound signal at an amplitude below a cavitation threshold of a medical target region in order to control growth of cavitation microbubbles in the target region; superimposing a high frequency signal onto the low frequency signal in order to produce a modulated signal having an amplitude that exceeds said cavitation threshold, said modulated signal having a focal zone of a size determined by the high frequency signal; and positioning the focal zone of the modulated signal into the medical target region in order to cause vaporous cavitation therein. - View Dependent Claims (17, 18, 19, 20)
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Specification