Injection system and pumping system for use therein

• US 5,827,219 A
• Filed: 05/31/1996
• Issued: 10/27/1998
• Est. Priority Date: 10/28/1993
• Status: Expired due to Term

• Current Assignee: Bayer Medical Care Inc. (Bayer AG)
• Original Assignee: Medrad Incorporated (Bayer AG)
• Inventors: Uber, Arthur E. III, Hirschman, Alan D., Havrilla, Joseph B.
• Primary Examiner(s): MENDEZ, MANUEL A
• Application Number:
  US08/655,886
• Time in Patent Office: 879 Days
• Field of Search: 604/65-67, 604/30-34, 604/49, 604/118, 604/151, 128/DIG. 12, 128/13
• US Class Current: 604/30
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 5/007 for contrast media
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407
• CPC Class Codes: A61M 5/16886 for measuring fluid flow rate, i.e. flowmeters
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence

Abstract

The present invention provides a number of pumping systems and injection systems particularly useful for injecting a liquid medium into a patient. In general, the pumping systems comprise a removable pumping unit. The removable pumping unit includes means for pressurizing the liquid medium via the rotational displacement of the liquid medium. The present invention also provides a pumping system comprising a pumping unit for pressurizing the liquid medium and a feedback-controlled drive means in connection with the pumping unit for providing a controlled powered drive to the pumping unit. The pumping system further comprises a flow meter for measuring the flow rate of the pressurized liquid medium exiting the pumping system and control means in communicative connection with the drive means for providing a control signal to control the powered drive provided to the pumping unit. The control means is suitable to receive a feedback signal from the flow meter corresponding to the flow rate of the pressurized liquid medium exiting the pumping unit. The control signal provided to the drive means is a function of the feedback signal.

Claims

1. A pumping system comprising:

a. a removable pumping unit comprising;

a non-deformable chamber comprising at least one inlet port for allowing a liquid medium to enter the chamber and an outlet port through which the liquid medium exits the chamber;

a rotary mechanism disposed in the chamber and in fluid contact with the liquid medium, the non-deformable chamber and the rotary mechanism cooperable to pressurize the liquid medium via rotational displacement thereof for pressurized injection into a patient; and

a drive connector operatively associated with the rotary mechanism; and

b. a drive housing adapted to receive said removable pumping unit, the drive housing comprising drive means for powering the rotary mechanism, the drive means comprising a drive coupling for removably engaging the drive connector on said removable pumping unit for providing a powered drive to the rotary mechanism;

whereby said removable pumping unit is suitable to be readily removed from connection with the drive means.

2. The pumping system of claim 1 wherein the removable pumping unit is fabricated from a polymeric material which is chemically and biochemically compatible with the liquid medium.

3. The pumping system of claim 1 wherein the rotary mechanism is adapted to allow a portion of the liquid medium within the chamber to flow in a direction reverse to the principal flow direction to reduce the risk of pumping air into the patient.

4. The pumping system of claim 1 further comprising a flow meter for measuring the flow rate of the pressurized liquid medium exiting the removable pumping unit and control means in connection with the drive means for providing a control signal to control the powered drive provided to the pumping unit, the control means being in communicative connection with the flow meter to receive a feedback signal from the flow meter corresponding to the flow rate of the pressurized liquid medium exiting the pumping unit, the control signal being responsive to the feedback signal.

5. The pumping system of claim 4 wherein the rotary mechanism is adapted to allow a portion of the liquid medium within the chamber to flow in a direction reverse to the principal flow direction to reduce the risk of pumping air into the patient.

6. The pumping system of claim 1, further comprising a clutch means in operative connection with the drive means.

7. The pumping system of claim 1 further comprising means for preventing pressure of the pressurized medium from exceeding a predetermined pressure.

8. An injection system comprising:

a. at least one container of liquid medium;

b. a pumping system in fluid connection with the liquid medium in said at least one container, said pumping system comprising;

i. a removable pumping unit comprising;

a non-deformable chamber comprising at least one inlet port in fluid connection with the at least one container for allowing the liquid medium to enter the chamber and an outlet port through which the liquid medium exits the chamber;

a rotary mechanism disposed in the chamber and in fluid contact with the liquid medium, the non-deformable chamber and the rotary mechanism cooperable to pressurize the liquid medium via rotational displacement thereof for pressurized injection into a patient; and

a drive connector operatively associated with the rotary mechanism; and

ii. a drive housing adapted to receive the removable pumping unit, the drive housing comprising drive means for powering the rotary mechanism, the drive means comprising a drive coupling for removably engaging the drive connector on the removable pumping unit for providing a powered drive to the rotary mechanism;

whereby the removable pumping unit is suitable to be readily removed from connection with the drive means; and

c. a disposable patient interface having a first end in fluid connection with the outlet port of the pumping unit and a second end in contact with the patient for injection of pressurized liquid medium into the patient.

9. The injection system of claim 8 further comprising means for detecting air bubbles placed in fluid connection with the medium container before the pumping system.

10. The injection system of claim 8 further comprising means for substantially eliminating air bubbles from the liquid medium, the means for substantially eliminating air bubbles being placed in fluid connection with the liquid medium container before the pumping system such that air bubbles are substantially eliminated from the liquid medium before the liquid medium reaches the pumping system.

11. The injection system of claim 8, further comprising valve means in fluid connection with the outlet port of the pumping unit for substantially ensuring unidirectional flow of the liquid medium, the valve means being placed before the patient interface.

12. The injection system of claim 8 further comprising means in fluid connection with the outlet port of the pumping unit for substantially removing air bubbles from the liquid medium, the removing means being placed prior to the patient interface.

13. The injection system of claim 8 wherein the removable pumping unit is fabricated from a polymeric material which is chemically and biochemically compatible with the liquid medium.

14. The injection system of claim 8 wherein the rotary mechanism is adapted to allow a portion of the liquid medium within the chamber to flow in a direction reverse to the principal flow direction to reduce the risk of pumping air into the patient.

15. The injection system of claim 8 further comprising a flow meter for measuring the flow rate of the pressurized liquid medium exiting the removable pumping unit and control means in connection with the drive means for providing a control signal to control the powered drive provided to the pumping unit, the control means being in communicative connection with the flow meter to receive a feedback signal from the flow meter corresponding to the flow rate of the pressurized liquid medium exiting the pumping unit, the control signal being responsive to the feedback signal.

16. The injection system of claim 15 wherein the rotary mechanism is adapted to allow a portion of the liquid medium within the chamber to flow in a direction reverse to the principal flow direction to reduce the risk of pumping air into the patient.

17. The pumping system of claim 8, further comprising a clutch means in operative connection with the drive means.

18. The pumping system of claim 8 further comprising means for preventing pressure of the pressurized medium from exceeding a predetermined pressure.

19. A pumping system comprising:

a. a removable pumping unit for pressurizing a liquid medium, the pumping unit comprising;

a non-deformable chamber comprising an inlet port for allowing a liquid medium to enter the chamber and an outlet port through which the liquid medium exits the chamber;

a rotary mechanism disposed in the chamber and in fluid contact with the liquid medium, the non-deformable chamber and the rotary mechanism cooperable to pressurize the liquid medium via rotational displacement thereof for pressurized injection into a patient; and

a drive connector operatively associated with the rotary mechanism;

b. a drive housing adapted to receive said removable pumping unit, the drive housing comprising drive means for powering the rotary mechanism, the drive means comprising a drive coupling for removably engaging the drive connector on said pumping unit for providing a powered drive to said pumping unit;

c. a flow meter in fluid communication with the liquid medium, said flow meter operable to measure the flow rate of the pressurized liquid medium exiting said pumping unit; and

d. a control system in communication with said flow meter and the drive means, said control system operable to receive a feedback signal from the flow meter corresponding to the flow rate of the pressurized liquid medium exiting said pumping unit and to generate a control signal responsive to the feedback signal to control the powered drive provided to said pumping unit, said flow meter and the control system cooperable to maintain a desired flow rate substantially independent of changes in input and output flow resistance and changes in the viscosity of the liquid medium.

20. The pumping system of claim 19 further comprising means for injecting the liquid medium into a patient.

21. A method of using a pumping system to inject a liquid medium into a patient, comprising the following steps:

providing a disposable pumping unit for pressurizing the liquid medium, the pumping unit comprising a non-deformable chamber comprising at least one inlet port for allowing the liquid medium to enter the chamber and an outlet port through which the liquid medium exits the chamber, a rotary mechanism disposed in the chamber and in fluid contact with the liquid medium, the non-deformable chamber and the rotary mechanism cooperable to pressurize the liquid medium via rotational displacement and compression thereof for pressurized injection into the patient, and a drive connector operatively associated with the rotary mechanism;

providing a drive housing adapted to receive the disposable pumping unit, the drive housing comprising drive means for powering the rotary mechanism, the drive means comprising a drive coupling for removably engaging the drive connector on the pumping unit for providing a powered drive to the rotary mechanism;

connecting the disposable pumping unit to the drive housing such that the drive coupling on the drive housing engages the drive connector on the disposable pumping unit;

providing at least one container of liquid medium;

connecting the at least one liquid medium container to the at least one inlet of the disposable pumping unit;

providing a disposable patient interface having first and second ends;

connecting the first end of the disposable patient interface to the outlet port of the disposable pumping unit;

connecting the second end of the disposable patient interface to the patient;

activating the drive means to power the rotary mechanism;

pressurizing the liquid medium in the disposable pumping unit through rotational displacement and compression thereof;

injecting the pressurized liquid medium into the patient through the disposable patient interface;

deactivating the drive means to terminate the injection of liquid medium into the patient;

disconnecting the second end of the disposable patient interface from the patient;

disconnecting the first end of the patient interface from the outlet port of the disposable pumping unit; and

disposing of the disposable patient interface.

22. The method of claim 21, further comprising the steps of:

providing a second disposable patient interface having first and second ends;

connecting the first end of the second disposable patient interface to the outlet port of the disposable pumping unit;

connecting the second end of the second disposable patient interface to the patient;

activating the drive means to power the rotary mechanism;

pressurizing the liquid medium in the disposable pumping unit through rotational displacement and compression thereof,

injecting the pressurized liquid medium into the patient through the second disposable patient interface;

deactivating the drive means to terminate the injection of liquid medium into the patient;

disconnecting the second end of the second disposable patient interface from the patient;

disconnecting the first end of the second patient interface from the outlet port of the disposable pumping unit; and

disposing of the second disposable patient interface.

23. The method of claim 22, further comprising the steps of:

disconnecting the at least one liquid medium container from the at least one inlet port of the disposable pumping unit;

disconnecting the disposable pumping unit from the drive housing; and

disposing of the disposable pumping unit.

24. The method of claim 23, further comprising the steps of:

providing a second disposable pumping unit;

connecting the second disposable pumping unit to the drive housing such that the drive coupling on the drive housing engages a drive connector on the second disposable pumping unit; and

connecting the at least one liquid medium container to the at least one inlet port of the second disposable pumping unit.

25. The method of claim 21, further comprising the steps of:

disconnecting the at least one liquid medium container from the at least one inlet port of the disposable pumping unit;

disconnecting the disposable pumping unit from the drive housing; and

disposing of the disposable pumping unit.

26. The method of claim 21, further comprising the step of sterilizing the disposable pumping unit before connecting the disposable pumping unit to the drive housing.

27. The method of claim 21 wherein the disposable pumping unit is formed from a polymeric material that is chemically and biochemically compatible with the liquid medium.

28. The method of claim 21 wherein the at least one inlet port comprises two inlet ports and the at least one container of liquid medium comprises two containers of liquid medium.